Objective
Studies performed at the universities of Nottingham, Edinburgh and Aberdeen have identified the insulin/IGF systems as a major putative mediator of nutritional influences on reproduction as this system exerts both endocrine and locally mediated effects on ovarian folliculogenesis, oogenesis and embryogenesis. However, little is known about the down-stream mechanisms that allow this regulation. Bioavailability of IGF-I at the ovary could be a key factor through effects on follicular and oocyte growth in addition to positive effects on embryo development. Preliminary results obtained by the applicant during the tenure of the previous Marie Cure action would suggest that IGF-I stimulates numerous cellular activities on follicular cells, including ligand-independent activation of the beta-oestrogen receptor, which could be used as an indirect marker of fertility. The continuing decline in fertility over the last years has a major impact on sustainability of dairy production, and therefore has considerable social consequences. This project will continue the previous experiments performed by the applicant at the University of Nottingham under the supervision of Prof. Webb and Prof. Flint aiming to identify a key step by which dietary inputs, in direct relation to the IGF system, affect dairy cow fertility.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences cell biology cell metabolism
- social sciences sociology demography fertility
- medical and health sciences health sciences nutrition
- agricultural sciences animal and dairy science domestic animals animal husbandry
- medical and health sciences clinical medicine embryology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BELLATERRA (CERDANYOLA DEL VALLES)
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.