Objective
This proposal is focused on More Efficient Cancer Therapies, topic of fundamental importance in the European Research Area and with high social impact worldwide. The Primary Scientific Aim of this proposal is to develop an efficient method for selective tumour delivery and cellular internalisation of therapeutic agents capable to modulate the activity of Bcl-2 proteins inducing apoptosis of tumour cells. This involves tackle an intracellular delivery problem of global importance in cancer therapy, which can be addressed by conjugation of the therapeutic agent through a rationally designed biodegradable linker either to a "Trojan peptide" or to a water-soluble polymeric carrier, working in this case within the novel area of Polymer Therapeutics. This research topic falls completely into the interface of polymer chemistry and the biomedical sciences and will hopefully give rise in the 21st century to a second generation of anticancer therapies with improved characteristics, higher tumour selectivity, higher efficiency and reduced systemic side effects. Polymer Therapeutics is a new area of research in the host institution, the CSAT at Valencia, applicant's region of origin, and almost unknown in Spain. Therefore, development of this proposal offers a highly innovative research approach, increasing the attractiveness and competitiveness of the host institution and Spain, contributing in this way to the European research excellence.
The CSAT is born devoted to reach the highest standards in basic research and to explore its putative industrial applications in order to improve the quality of life and health of the community. Its aims together with the advanced multidisciplinary training offered by the host institution not only will reinforced the applicant's scientific knowledge but will give her the necessary management skills to reach professional maturity and become independent researcher in cancer research field, settling the basis of a promising future career.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences chemical sciences polymer sciences
- medical and health sciences clinical medicine oncology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VALENCIA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.