3D Scaffolds as a Stem Cell Delivery System for Musculoskeletal Regenerative Medicine

Project Information

CELL HYBRIDGE

Grant agreement ID: 637308

DOI 10.3030/637308

Project closed

EC signature date 24 March 2015

Start date 1 May 2015

End date 30 April 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

UNIVERSITEIT MAASTRICHT
Netherlands

Publications

Peer reviewed articles (11)

Corrigendum to “Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering” Acta Biomater. 59 (2017) 82–93

Author(s): Honglin Chen, Xiaobin Huang, Minmin Zhang, Febriyani Damanik, Matthew B. Baker, Anne Leferink, Huipin Yuan, Roman Truckenmüller, Clemens van Blitterswijk, Lorenzo Moroni
Published in: Acta Biomaterialia, 2018, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2018.01.030

Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering

Author(s): Honglin Chen, Xiaobin Huang, Minmin Zhang, Febriyani Damanik, Matthew B. Baker, Anne Leferink, Huipin Yuan, Roman Truckenmüller, Clemens van Blitterswijk, Lorenzo Moroni
Published in: Acta Biomaterialia, Issue 59, 2017, Page(s) 82-93, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2017.07.003

A quantitative method to analyse F-actin distribution in cells

Author(s): Jip Zonderland, Paul Wieringa, Lorenzo Moroni
Published in: MethodsX, Issue 6, 2019, Page(s) 2562-2569, ISSN 2215-0161
Publisher: Elsevier
DOI: 10.1016/j.mex.2019.10.018

From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation

Author(s): Honglin Chen, Danielle F. Baptista, Giuseppe Criscenti, João Crispim, Hugo Fernandes, Clemens van Blitterswijk, Roman Truckenmüller, Lorenzo Moroni
Published in: Nanoscale, Issue 11/30, 2019, Page(s) 14312-14321, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8nr10108f

Additive manufacturing of an elastic poly(ester)urethane for cartilage tissue engineering

Author(s): Sandra Camarero-Espinosa, Andrea Calore, Arnold Wilbers, Jules Harings, Lorenzo Moroni
Published in: Acta Biomaterialia, 2019, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2019.11.041

Bioprinting: From Tissue and Organ Development to in Vitro Models

Author(s): Carlos Mota, Sandra Camarero-Espinosa, Matthew B. Baker, Paul Wieringa, Lorenzo Moroni
Published in: Chemical Reviews, 2020, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.9b00789

Mechanosensitive regulation of stanniocalcin-1 by zyxin and actin-myosin in human mesenchymal stromal cells

Author(s): Jip Zonderland, David B. Gomes, Yves Pallada, Ivan L. Moldero, Sandra Camarero-Espinosa, Lorenzo Moroni
Published in: STEM CELLS, Issue 38/8, 2020, Page(s) 948-959, ISSN 1066-5099
Publisher: AlphaMed Press Inc
DOI: 10.1002/stem.3198

Fiber diameter, porosity and functional group gradients in electrospun scaffolds

Author(s): Jip Zonderland, Silvia Rezzola, Paul Wieringa, Lorenzo Moroni
Published in: Biomedical Materials, Issue 15/4, 2020, Page(s) 045020, ISSN 1748-605X
Publisher: IOP
DOI: 10.1088/1748-605x/ab7b3c

Dimensionality changes actin network through lamin A/C and zyxin

Author(s): Jip Zonderland, Ivan Lorenzo Moldero, Shivesh Anand, Carlos Mota, Lorenzo Moroni
Published in: Biomaterials, Issue 240, 2020, Page(s) 119854, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.119854

Additive manufactured, highly resilient, elastic, and biodegradable poly(ester)urethane scaffolds with chondroinductive properties for cartilage tissue engineering

Author(s): S. Camarero-Espinosa, C. Tomasina, A. Calore, L. Moroni
Published in: Materials Today Bio, Issue 6, 2020, Page(s) 100051, ISSN 2590-0064
Publisher: Elsevier
DOI: 10.1016/j.mtbio.2020.100051

Tissue Engineering and Regenerative Medicine 2019: The Role of Biofabrication—A Year in Review

Author(s): Tiago Ramos, Lorenzo Moroni
Published in: Tissue Engineering Part C: Methods, Issue 26/2, 2020, Page(s) 91-106, ISSN 1937-3384
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2019.0344

Other (1)

Full cell infiltration and thick tissue formation in vivo in tailored electrospun scaffolds

Author(s): Jip Zonderland, Silvia Rezzola, David Gomes, Sandra Camarero Espinosa, Ana Henriques Ferreira Lourenço, Andrada Serafim, Izabela Cristina Stancu, David Koper, Hong Liu, Pamela Habibovic, Peter Kessler, Marloes Peters, Peter Emans, Nicole Bouvy, Paul Wieringa, Lorenzo Moroni
Published in: 2020
Publisher: BiorXiv
DOI: 10.1101/2020.02.19.955948

Intellectual Property Rights

Patent (3)

Scaffold comprising buckled fibers

Application/Publication number: WIPO PCT/EP2015/069687
Date: 2015-08-27

Scaffold comprising buckled fibers

Application/Publication number: WIPO PCT/EP2015/069687
Date: 2015-08-27

Scaffold comprising buckled fibers

Application/Publication number: WIPO PCT/EP2015/069687
Date: 2015-08-27