Elucidation of the evolution of post-transcriptional regulation by characterizing the cnidarian microRNA pathway

Project Information

CNIDARIAMICRORNA

Grant agreement ID: 637456

DOI 10.3030/637456

Project closed

EC signature date 30 March 2015

Start date 1 May 2015

End date 30 April 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 587,00

EU contribution € 1 499 587,00

Coordinated by

THE HEBREW UNIVERSITY OF JERUSALEM
Israel

Publications

Peer reviewed articles (9)

Unravelling the developmental and functional significance of an ancient Argonaute duplication

Author(s): Arie Fridrich, Vengamanaidu Modepalli, Magda Lewandowska, Reuven Aharoni, Yehu Moran
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20003-8

Evolution of miRNA Tailing by 3′ Terminal Uridylyl Transferases in Metazoa

Author(s): Vengamanaidu Modepalli, Yehu Moran
Published in: Genome Biology and Evolution, Issue 9/6, 2017, Page(s) 1547-1560, ISSN 1759-6653
Publisher: Oxford University Press
DOI: 10.1093/gbe/evx106

The evolutionary origin of plant and animal microRNAs

Author(s): Yehu Moran, Maayan Agron, Daniela Praher, Ulrich Technau
Published in: Nature Ecology & Evolution, Issue 1/3, 2017, Page(s) 0027, ISSN 2397-334X
Publisher: Springer Nature
DOI: 10.1038/s41559-016-0027

Characterization of the piRNA pathway during development of the sea anemone Nematostella vectensis

Author(s): Daniela Praher, Bob Zimmermann, Grigory Genikhovich, Yaara Columbus-Shenkar, Vengamanaidu Modepalli, Reuven Aharoni, Yehu Moran, Ulrich Technau
Published in: RNA Biology, Issue 14/12, 2017, Page(s) 1727-1741, ISSN 1547-6286
Publisher: Landes Bioscience
DOI: 10.1080/15476286.2017.1349048

The methyltransferase HEN1 is required in Nematostella vectensis for microRNA and piRNA stability as well as larval metamorphosis

Author(s): Vengamanaidu Modepalli, Arie Fridrich, Maayan Agron, Yehu Moran
Published in: PLOS Genetics, Issue 14/8, 2018, Page(s) e1007590, ISSN 1553-7390
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1007590

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution

Author(s): Marta Mauri, Marieluise Kirchner, Reuven Aharoni, Camilla Ciolli Mattioli, David van den Bruck, Nadya Gutkovitch, Vengamanaidu Modepalli, Matthias Selbach, Yehu Moran, Marina Chekulaeva
Published in: Nucleic Acids Research, Issue 45/2, 2017, Page(s) 938-950, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkw792

Too Many False Targets for MicroRNAs: Challenges and Pitfalls in Prediction of miRNA Targets and Their Gene Ontology in Model and Non‐model Organisms

Author(s): Arie Fridrich, Yael Hazan, Yehu Moran
Published in: BioEssays, Issue 41/4, 2019, Page(s) 1800169, ISSN 0265-9247
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/bies.201800169

Initial Virome Characterization of the Common Cnidarian Lab Model Nematostella vectensis

Author(s): Magda Lewandowska, Yael Hazan, Yehu Moran
Published in: Viruses, Issue 12/2, 2020, Page(s) 218, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12020218

Conservation and turnover of miRNAs and their highly complementary targets in early branching animals

Author(s): Daniela Praher, Bob Zimmermann, Rohit Dnyansagar, David J. Miller, Aurelie Moya, Vengamanaidu Modepalli, Arie Fridrich, Daniel Sher, Lene Friis-Møller, Per Sundberg, Sylvain Fôret, Regan Ashby, Yehu Moran, Ulrich Technau
Published in: Proceedings of the Royal Society B: Biological Sciences, Issue 288/1945, 2021, Page(s) 20203169, ISSN 0962-8452
Publisher: Royal Society of London
DOI: 10.1098/rspb.2020.3169