Structural studies of mammalian Cys-loop receptors

Project Information

PentaBrain

Grant agreement ID: 637733

DOI

10.3030/637733

Project closed

EC signature date 22 April 2015

Start date 1 June 2015

End date 30 November 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Thesis and dissertations (1)

Etudes Structurales du récepteur 5-HT3

Author(s): Lucie Polovinkin
Published in: 2019
Publisher: N/A

Peer reviewed articles (5)

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

Author(s): Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M,Chaumont-Dubel S,Claeysen S,Cunningham KA,Fone KC,Gershon M,Di Giovanni G,Goodfellow NM,Halberstadt AL,Hartley RM,Hassaine G,Herrick-Davis K,Hovius R,Lacivita E,Lambe EK,Leopoldo M,Levy FO,Lummis SCR,Marin P,Maroteaux L,McCreary AC,Nelson DL,Neumaier JF,Newman-Tancredi A, Nury H, Roberts A,Roth BL,Roumier A,Sanger GJ,Teitler M,Sharp T,Villal
Published in: Pharmacol. Rev., 2021, ISSN 0031-6997
Publisher: American Society for Pharmacology and Experimental Therapeutics
DOI: 10.1124/pr.118.015552

Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

Author(s): Uchański T,Masiulis S,Fischer B,Kalichuk V, López-Sánchez U, Zarkadas E, Weckener M,Sente A,Ward P,Wohlkönig A,Zögg T,Remaut H,Naismith JH,Nury H,Vranken W,Aricescu AR,Pardon E,Steyaert J
Published in: Nature Methods, 2021, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-020-01001-6

The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor

Author(s): Zarkadas E,Zhang H,Cai W,Effantin G,Perot J,Neyton J,Chipot C,Schoehn G,Dehez F,Nury H
Published in: Structure, 2020, ISSN 0969-2126
Publisher: Cell Press
DOI: 10.1016/j.str.2020.07.004

Conformational transitions of the serotonin 5-HT3 receptor

Author(s): Lucie Polovinkin, Ghérici Hassaine, Jonathan Perot, Emmanuelle Neumann, Anders A. Jensen, Solène N. Lefebvre, Pierre-Jean Corringer, Jacques Neyton, Christophe Chipot, Francois Dehez, Guy Schoehn, Hugues Nury
Published in: Nature, Issue 563/7730, 2018, Page(s) 275-279, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-018-0672-3

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel

Author(s): Hénault CM,Govaerts C,Spurny R,Brams M,Estrada-Mondragon A,Lynch J,Bertrand D,Pardon E,Evans GL,Woods K,Elberson BW,Cuello LG,Brannigan G,Nury H,Steyaert J,Baenziger JE,Ulens C
Published in: Nat. Chem. Biol., 2019, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/s41589-019-0369-4

Book chapters (1)

Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor

Author(s): Ghérici Hassaïne, Cédric Deluz, Luigino Grasso, Romain Wyss, Ruud Hovius, Henning Stahlberg, Takashi Tomizaki, Aline Desmyter, Christophe Moreau, Lucie Peclinovska, Sonja Minniberger, Lamia Mebarki, Xiao-Dan Li, Horst Vogel, Hugues Nury
Published in: Methods in Molecular Biology, Membrane Protein Structure and Function Characterization, 2017, Page(s) 139-168
Publisher: Springer New York
DOI: 10.1007/978-1-4939-7151-0_8