The Crosstalk Between Red And White Blood Cells: The Case Of Fish

Project Information

BLOODCELLSCROSSTALK

Grant agreement ID: 639249

DOI

10.3030/639249

Project closed

EC signature date 17 February 2015

Start date 1 April 2015

End date 31 October 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 823 250,00

EU contribution

€ 1 823 250,00

Coordinated by

UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Conference proceedings (8)

RNA-SEQ OF RAINBOW TROUT RBCs TRANSFECTED WITH A DNA VACCINE IN VITRO SHOWS A POTENTIAL ROLE OF TROUT RBCs AS MEDIATORS IN THE IMMUNE RESPONSE INDUCED BY DNA VACCINES IN FISH.

Author(s): Sara Puente, Ivan Nombela, Veronica Chico, Julio Coll, Luis Mercado, Maria del Mar Ortega-Villaizán
Published in: 2017 International Society of Vaccines. Annual Congress 5th‐7th October 2017, Institut Pasteur, Paris, France, 2017
Publisher: International Society of Vaccines and ISV Congress

Proteomic study of VHSV infected trout RBCs

Author(s): Verónica Chico,Ivan Nombela, Sara Puente-Marín, Sergio Ciordia, Maria Carmen Mena, Julio Coll, Maria del Mar Ortega-Villaizan
Published in: 10TH INTERNATIONAL SYMPOSIUM ON VIRUSES OF LOWER VERTEBRATES (ISVLV), Budapest, Hungary, 2017
Publisher: European Society for Virology

Fish red blood cells halted VHSV and IPNV infections together with mounting antiviral immune responses

Author(s): Ivan Nombela, Sara Puente-Marin, Veronica Chico, Luis Mercado, Luis Perez, Julio M. Coll, Amparo Estepa, Maria del Mar Ortega-Villaizan
Published in: 10TH INTERNATIONAL SYMPOSIUM ON VIRUSES OF LOWER VERTEBRATES (ISVLV), Budapest, Hungary, 2017
Publisher: European Society for Virology

Potential role of rainbow trout red blood cells as mediators in the immune response induced by DNA vaccines

Author(s): S. Puente-Marin, I. Nombela, V. Chico, S. Ciordia, M.C. Mena, J. Coll, L. Mercado, M. Ortega-Villaizán
Published in: Fish & Shellfish Immunology, Issue 91, 2019, Page(s) 425, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2019.04.164

NKEF, an antiviral protein involved in the immune response of rainbow trout red blood cells

Author(s): M. Salvador-Mira, V. Chico, I. Nombela, S. Puente-Marin, S. Ciordia, M.C. Mena, L. Mercado, M. Ortega-Villaizan
Published in: Fish & Shellfish Immunology, Issue 91, 2019, Page(s) 409, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2019.04.123

Rainbow trout shape-shifted red blood cells

Author(s): V. Chico, S. Puente-Marin, I. Nombela, S. Ciordia, M.C. Mena, B. Carracedo, A. Villena, L. Mercado, J. Coll, M. Ortega-Villaizan
Published in: Fish & Shellfish Immunology, Issue 91, 2019, Page(s) 408, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2019.04.122

Transcriptome and proteome analyses of red blood cells from rainbow trout challenged with viral haemorrhagic septicaemia virus

Author(s): I. Nombela, M. Lopez-Lorigados, S. Puente-Marin, V. Chico, S. Ciordia, M.C. Mena, J. Coll, L. Mercado, L. Perez, M. Ortega-Villaizan
Published in: Fish & Shellfish Immunology, Issue 91, 2019, Page(s) 440, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2019.04.206

IFIT5 participates in the antiviral mechanisms of rainbow trout red blood cells

Author(s): V. Chico, M. Salvador-Mira, I. Nombela, S. Puente-Marin, S. Ciordi, M.C. Mena, L. Perez, J. Coll, F. Guzman, J. Encinar, L. Mercado, M. Ortega-Villaizan
Published in: Fish & Shellfish Immunology, Issue 91, 2019, Page(s) 469, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2019.04.284

Peer reviewed articles (12)

Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus

Author(s): Ivan Nombela, Sara Puente-Marin, Veronica Chico, Alberto J. Villena, Begoña Carracedo, Sergio Ciordia, Maria Carmen Mena, Luis Mercado, Luis Perez, Julio Coll, Amparo Estepa, Maria del Mar Ortega-Villaizan
Published in: F1000Research, Issue 6, 2017, Page(s) 1958, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.12985.2

Infectious pancreatic necrosis virus triggers antiviral immune response in rainbow trout red blood cells, despite not being infective

Author(s): Ivan Nombela, Aurora Carrion, Sara Puente-Marin, Verónica Chico, Luis Mercado, Luis Perez, Julio Coll, Maria del Mar Ortega-Villaizan
Published in: F1000Research, Issue 6, 2017, Page(s) 1968, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.12994.2

In Silico Functional Networks Identified in Fish Nucleated Red Blood Cells by Means of Transcriptomic and Proteomic Profiling

Author(s): Sara Puente-Marin, Iván Nombela, Sergio Ciordia, María Mena, Verónica Chico, Julio Coll, María Ortega-Villaizan
Published in: Genes, Issue 9/4, 2018, Page(s) 202, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes9040202

Shape-Shifted Red Blood Cells: A Novel Red Blood Cell Stage?

Author(s): Verónica Chico, Sara Puente-Marin, Iván Nombela, Sergio Ciordia, María Mena, Begoña Carracedo, Alberto Villena, Luis Mercado, Julio Coll, María Ortega-Villaizan
Published in: Cells, Issue 7/4, 2018, Page(s) 31, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells7040031

Nucleated red blood cells: Immune cell mediators of the antiviral response

Author(s): Ivan Nombela, Maria del Mar Ortega-Villaizan
Published in: PLOS Pathogens, Issue 14/4, 2018, Page(s) e1006910, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1006910

Rainbow Trout Erythrocytes ex vivo Transfection With a DNA Vaccine Encoding VHSV Glycoprotein G Induces an Antiviral Immune Response

Author(s): Sara Puente-Marin, Ivan Nombela, Veronica Chico, Sergio Ciordia, Maria Carmen Mena, Julio Coll, Luis Mercado, Maria Del Mar Ortega-Villaizan
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.02477

The Megalocytivirus RBIV Induces Apoptosis and MHC Class I Presentation in Rock Bream (Oplegnathus fasciatus) Red Blood Cells

Author(s): Myung-Hwa Jung, Verónica Chico, Sergio Ciordia, Maria Carmen Mena, Sung-Ju Jung, Maria Del Mar Ortega-Villaizan
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.00160

IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells

Author(s): Veronica Chico, Maria Elizabhet Salvador-Mira, Ivan Nombela, Sara Puente-Marin, Sergio Ciordia, María Carmen Mena, Luis Perez, Julio Coll, Fanny Guzman, Jose Antonio Encinar, Luis Mercado, Maria del Mar Ortega-Villaizan
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.00613

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers

Author(s): Ivan Nombela, Ricardo Requena-Platek, Byron Morales-Lange, Veronica Chico, Sara Puente-Marin, Sergio Ciordia, Maria Carmen Mena, Julio Coll, Luis Perez, Luis Mercado, Maria del Mar Ortega-Villaizan
Published in: Cells, Issue 8/5, 2019, Page(s) 386, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8050386

Fish Red Blood Cells Modulate Immune Genes in Response to Bacterial Inclusion Bodies Made of TNFα and a G-VHSV Fragment

Author(s): Sara Puente-Marin, Rosemary Thwaite, Luis Mercado, Julio Coll, Nerea Roher, Maria Del Mar Ortega-Villaizan
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.01055

Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets

Author(s): Nombela, Lopez-Lorigados, Salvador-Mira, Puente-Marin, Chico, Ciordia, Mena, Mercado, Coll, Perez, Ortega-Villaizan
Published in: Vaccines, Issue 7/3, 2019, Page(s) 63, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines7030063

Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish

Author(s): Puente-Marin, Nombela, Chico, Ciordia, Mena, Perez, Coll, Ortega-Villaizan
Published in: Vaccines, Issue 7/3, 2019, Page(s) 60, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines7030060

Book chapters (1)

Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens

Author(s): Verónica Chico, Ivan Nombela, Sara Puente-Marín, María del Mar Ortega-Villaizan
Published in: Immune Response Activation and Immunomodulation, 2019, ISBN 978-1-78985-151-9
Publisher: IntechOpen
DOI: 10.5772/intechopen.80545