Strategies Targeting Thyroid Hormone in Athrophy Related Syndromes

Project Information

STARS

Grant agreement ID: 639548

DOI

10.3030/639548

Project closed

EC signature date 10 July 2015

Start date 1 August 2015

End date 31 July 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 310 000,00

EU contribution

€ 1 310 000,00

Coordinated by

UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

Author(s): Emery Di Cicco, Carla Moran, W. Edward Visser, Annarita Nappi, Erik Schoenmakers, Pamela Todd, Greta Lyons, Mehul Dattani, Raffaele Ambrosio, Silvia Parisi, Domenico Salvatore, Krishna Chatterjee, Monica Dentice
Published in: Thyroid, Issue 31/7, 2021, Page(s) 1114-1126, ISSN 1050-7256
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2020.0391

Thyroid hormone promotes differentiation of colon cancer stem cells

Author(s): Annunziata Gaetana Cicatiello, Raffaele Ambrosio, Monica Dentice
Published in: Molecular and Cellular Endocrinology, Issue 459, 2017, Page(s) 84-89, ISSN 0303-7207
Publisher: Elsevier BV
DOI: 10.1016/j.mce.2017.03.017

Metabolic Effects of the Intracellular Regulation of Thyroid Hormone: Old Players, New Concepts

Author(s): Cicatiello AG, Di Girolamo D, Dentice M
Published in: Front Endocrinol, 2018, ISSN 1664-2392
Publisher: Frontiers
DOI: 10.3389/fendo.2018.00474

Deiodinases and their intricate role in thyroid hormone homeostasis

Author(s): Cristina Luongo, Monica Dentice, Domenico Salvatore
Published in: Nature Reviews Endocrinology, Issue 15/8, 2019, Page(s) 479-488, ISSN 1759-5029
Publisher: Nature Publishing Group
DOI: 10.1038/s41574-019-0218-2

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation

Author(s): Gennaro Riccio, Eduardo Sommella, Nadia Badolati, Emanuela Salviati, Sara Bottone, Pietro Campiglia, Monica Dentice, Gian Tenore, Mariano Stornaiuolo, Ettore Novellino
Published in: Nutrients, Issue 10/11, 2018, Page(s) 1808, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu10111808

The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress

Author(s): Serena Sagliocchi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Raffaele Ambrosio, Caterina Miro, Daniela Di Girolamo, Annarita Nappi, Giuseppina Mancino, Maria Angela De Stefano, Cristina Luongo, Maddalena Raia, Ashley N. Ogawa-Wong, Ann Marie Zavacki, Simona Paladino, Domenico Salvatore, Monica Dentice
Published in: Redox Biology, Issue 24, 2019, Page(s) 101228, ISSN 2213-2317
Publisher: Elsevier BV
DOI: 10.1016/j.redox.2019.101228

A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells

Author(s): Eduardo Sommella, Nadia Badolati, Gennaro Riccio, Emanuela Salviati, Sara Bottone, Monica Dentice, Pietro Campiglia, Gian Tenore, Mariano Stornaiuolo, Ettore Novellino
Published in: Nutrients, Issue 11/1, 2019, Page(s) 163, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11010163

The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation

Author(s): Giuseppina Mancino, Annarita Sibilio, Cristina Luongo, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Annarita Nappi, Serena Sagliocchi, Raffaele Ambrosio, Maria Angela De Stefano, Daniela Di Girolamo, Tommaso Porcelli, Melania Murolo, Federica Saracino, Giuseppe Perruolo, Pietro Formisano, Mariano Stornaiuolo, Monica Dentice
Published in: Thyroid, 2020, ISSN 1050-7256
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2019.0557

The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas

Author(s): Annarita Nappi, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Giuseppina Mancino, Raffaele Ambrosio, Cristina Luongo, Daniela Di Girolamo, Maria Angela De Stefano, Tommaso Porcelli, Mariano Stornaiuolo, Monica Dentice
Published in: Cancers, Issue 12/3, 2020, Page(s) 715, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12030715

Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch

Author(s): Caterina Miro, Emery Di Cicco, Raffaele Ambrosio, Giuseppina Mancino, Daniela Di Girolamo, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Annarita Nappi, Maria Angela De Stefano, Cristina Luongo, Dario Antonini, Feliciano Visconte, Silvia Varricchio, Gennaro Ilardi, Luigi Del Vecchio, Stefania Staibano, Anita Boelen, Cedric Blanpain, Caterina Missero, Domenico Salvatore, Monica Dentice
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13140-2

Selective Inhibition of Genomic and Non-Genomic Effects of Thyroid Hormone Regulates Muscle Cell Differentiation and Metabolic Behavior

Author(s): Annarita Nappi, Melania Murolo, Serena Sagliocchi, Caterina Miro, Annunziata Gaetana Cicatiello, Emery Di Cicco, Rossella Di Paola, Maddalena Raia, Lucia D’Esposito, Mariano Stornaiuolo, Monica Dentice
Published in: International Journal of Molecular Sciences, Issue 22/13, 2021, Page(s) 7175, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22137175

Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas

Author(s): Caterina Miro, Annarita Nappi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Serena Sagliocchi, Melania Murolo, Valentina Belli, Teresa Troiani, Sandra Albanese, Sara Amiranda, Ann Marie Zavacki, Mariano Stornaiuolo, Marcello Mancini, Domenico Salvatore, Monica Dentice
Published in: Cancers, Issue 13/11, 2021, Page(s) 2743, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13112743