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Amyotrophic Lateral Sclerosis from a cortical perspective: towards alternative therapeutic strategies

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Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis

Author(s): Aurore Brunet, Geoffrey Stuart-Lopez, Thibaut Burg, Jelena Scekic-Zahirovic, Caroline Rouaux
Published in: Frontiers in Neuroscience, 14, 2020, Page(s) 1-14, ISSN 1662-453X
Publisher: frontiers in Neuroscience
DOI: 10.3389/fnins.2020.00363

Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis

Author(s): Thibaut Burg, Charlotte Bichara, Jelena Scekic‐Zahirovic, Mathieu Fischer, Geoffrey Stuart‐Lopez, Aurore Brunet, François Lefebvre, Matilde Cordero‐Erausquin, Caroline Rouaux
Published in: Annals of Neurology, 88/4, 2020, Page(s) 688-702, ISSN 0364-5134
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ana.25833

Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis

Author(s): Michael Tibshirani, Beibei Zhao, Benoit J Gentil, Sandra Minotti, Christine Marques, Julia Keith, Ekaterina Rogaeva, Lorne Zinman, Caroline Rouaux, Janice Robertson, Heather D Durham
Published in: Human Molecular Genetics, 26/21, 2017, Page(s) 4142-4152, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx301

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Author(s): Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouaux
Published in: Brain Sciences, 11/3, 2021, Page(s) 369, ISSN 2076-3425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci11030369

Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism

Author(s): Jelena Scekic-Zahirovic, Mathieu Fischer, Geoffrey Stuart-Lopez, Thibaut Burg, Johan Gilet, Sylvie Dirrig-Grosch, Christine Marques, Marie-Christine Birling, Pascal Kessler, Caroline Rouaux
Published in: Progress in Neurobiology, 2020, Page(s) 1-18, ISSN 0301-0082
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.pneurobio.2020.101972

Early alterations of RNA metabolism and splicing from adult corticospinal neurons in an ALS mouse model

Author(s): Christine Marques, Mathieu Fischer, Céline Keime, Thibaut Burg, Aurore Brunet, Jelena Scekic-Zahirovic, Caroline Rouaux
Published in: bioRxiv, 2019
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/667733