Amyotrophic Lateral Sclerosis from a cortical perspective: towards alternative therapeutic strategies

Project Information

CorticALS

Grant agreement ID: 639737

DOI

10.3030/639737

Project closed

EC signature date 24 March 2015

Start date 1 April 2015

End date 31 March 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis

Author(s): Aurore Brunet, Geoffrey Stuart-Lopez, Thibaut Burg, Jelena Scekic-Zahirovic, Caroline Rouaux
Published in: Frontiers in Neuroscience, Issue 14, 2020, Page(s) 1-14, ISSN 1662-453X
Publisher: frontiers in Neuroscience
DOI: 10.3389/fnins.2020.00363

Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis

Author(s): Thibaut Burg, Charlotte Bichara, Jelena Scekic‐Zahirovic, Mathieu Fischer, Geoffrey Stuart‐Lopez, Aurore Brunet, François Lefebvre, Matilde Cordero‐Erausquin, Caroline Rouaux
Published in: Annals of Neurology, Issue 88/4, 2020, Page(s) 688-702, ISSN 0364-5134
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ana.25833

Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis

Author(s): Michael Tibshirani, Beibei Zhao, Benoit J Gentil, Sandra Minotti, Christine Marques, Julia Keith, Ekaterina Rogaeva, Lorne Zinman, Caroline Rouaux, Janice Robertson, Heather D Durham
Published in: Human Molecular Genetics, Issue 26/21, 2017, Page(s) 4142-4152, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx301

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Author(s): Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouaux
Published in: Brain Sciences, Issue 11/3, 2021, Page(s) 369, ISSN 2076-3425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci11030369

Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism

Author(s): Jelena Scekic-Zahirovic, Mathieu Fischer, Geoffrey Stuart-Lopez, Thibaut Burg, Johan Gilet, Sylvie Dirrig-Grosch, Christine Marques, Marie-Christine Birling, Pascal Kessler, Caroline Rouaux
Published in: Progress in Neurobiology, 2020, Page(s) 1-18, ISSN 0301-0082
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.pneurobio.2020.101972

Other (1)

Early alterations of RNA metabolism and splicing from adult corticospinal neurons in an ALS mouse model

Author(s): Christine Marques, Mathieu Fischer, Céline Keime, Thibaut Burg, Aurore Brunet, Jelena Scekic-Zahirovic, Caroline Rouaux
Published in: bioRxiv, 2019
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/667733