Amyotrophic Lateral Sclerosis from a cortical perspective: towards alternative therapeutic strategies

Informazioni relative al progetto

CorticALS

ID dell’accordo di sovvenzione: 639737

DOI 10.3030/639737

Progetto chiuso

Data della firma CE 24 Marzo 2015

Data di avvio 1 Aprile 2015

Data di completamento 31 Marzo 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

Pubblicazioni

Peer reviewed articles (5)

Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis

Autori: Aurore Brunet, Geoffrey Stuart-Lopez, Thibaut Burg, Jelena Scekic-Zahirovic, Caroline Rouaux
Pubblicato in: Frontiers in Neuroscience, Numero 14, 2020, Pagina/e 1-14, ISSN 1662-453X
Editore: frontiers in Neuroscience
DOI: 10.3389/fnins.2020.00363

Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis

Autori: Thibaut Burg, Charlotte Bichara, Jelena Scekic‐Zahirovic, Mathieu Fischer, Geoffrey Stuart‐Lopez, Aurore Brunet, François Lefebvre, Matilde Cordero‐Erausquin, Caroline Rouaux
Pubblicato in: Annals of Neurology, Numero 88/4, 2020, Pagina/e 688-702, ISSN 0364-5134
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ana.25833

Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis

Autori: Michael Tibshirani, Beibei Zhao, Benoit J Gentil, Sandra Minotti, Christine Marques, Julia Keith, Ekaterina Rogaeva, Lorne Zinman, Caroline Rouaux, Janice Robertson, Heather D Durham
Pubblicato in: Human Molecular Genetics, Numero 26/21, 2017, Pagina/e 4142-4152, ISSN 0964-6906
Editore: Oxford University Press
DOI: 10.1093/hmg/ddx301

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Autori: Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouaux
Pubblicato in: Brain Sciences, Numero 11/3, 2021, Pagina/e 369, ISSN 2076-3425
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci11030369

Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism

Autori: Jelena Scekic-Zahirovic, Mathieu Fischer, Geoffrey Stuart-Lopez, Thibaut Burg, Johan Gilet, Sylvie Dirrig-Grosch, Christine Marques, Marie-Christine Birling, Pascal Kessler, Caroline Rouaux
Pubblicato in: Progress in Neurobiology, 2020, Pagina/e 1-18, ISSN 0301-0082
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.pneurobio.2020.101972

Other (1)

Early alterations of RNA metabolism and splicing from adult corticospinal neurons in an ALS mouse model

Autori: Christine Marques, Mathieu Fischer, Céline Keime, Thibaut Burg, Aurore Brunet, Jelena Scekic-Zahirovic, Caroline Rouaux
Pubblicato in: bioRxiv, 2019
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/667733