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Optical Coherence Tomography for Intraocular Lenses

Objective

The replacement of the crystalline lens of the eye by an artificial intraocular lens (IOL) is one of the most frequent procedures worldwide (3 millions/year in Western Europe). The surgery is required to correct for the age-related loss in transparency (cataract), but it is also performed to correct for refractive errors, and may be envisioned to correct for presbyopia in a younger population (>45) with future accommodating IOLs that restore the eye focusing capability. Despite the development of new IOL designs and a steady market growth of IOLs (particularly of Premium IOLs, aiming at delivering optimal vision quality to the patient), the techniques to select the optimal IOL design have not evolved at a similar pace. As cataract surgery moves into new paradigms, access to ocular imaging-based technologies that allow accurate selection of the IOL and evaluation of the surgical outcomes becomes essential.

The PRESBYOPIA ERC-Advanced Grant investigates basic mechanisms of the crystalline lens accommodation, to propose nature-inspired IOL designs to correct presbyopia. With this aim, we have developed a laboratory prototype for full 3-D quantitative anterior segment Optical Coherence Tomography (OCT) based on our proprietary method to reduce distortion and automatic quantification. We have demonstrated the capabilities of this instrument to provide accurate crystalline lens topography in vivo and full 3-D optical biometry in cataract patients pre- and post- implantation of IOLs.

The OCT4IOL ERC-Proof of Concept will evaluate the marketability of this OCT line, generate new IP, developing a product commercialization plan, and reaching a strategic partnership alliance, with the ultimate goal of developing an instrument that brings eye surgery into new paradigms for IOL selection and customization in cataract surgery.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2014-PoC

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Host institution

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
CALLE SERRANO 117
28006 MADRID
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 150 000,00

Beneficiaries (1)

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