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Functional and Molecular Analyses of the Interplay between Hematopoietic and Mesenchymal Niche Cells in Human Myelodysplastic Syndromes.

Publications

AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia

Author(s): Irene Tirado-Gonzalez, Arnaud Descot, Devona Soetopo, Aleksandra Nevmerzhitskaya, Alexander Schaffer, Ivan-Maximiliano Kur, Ewelina Czlonka, Carolin Wachtel, Ioanna Tsoukala, Luise Muller, Anna-Lena Schafer, Maresa Weitmann, Petra Dinse, Emily Alberto, Michele C Buck, Jonathan J M Landry, Bianka Baying, Julia Slotta-Huspenina, Jenny Roesler, Patrick N Harter, Anne-Sophie Kubasch, Jörn Meinel, Eim
Published in: Cancer Discovery, 2021, Page(s) candisc.1378.2020, ISSN 2159-8274
DOI: 10.1158/2159-8290.cd-20-1378

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Author(s): M. Mossner, J.-C. Jann, J. Wittig, F. Nolte, S. Fey, V. Nowak, J. Oblander, J. Pressler, I. Palme, C. Xanthopoulos, T. Boch, G. Metzgeroth, H. Rohl, S. H. Witt, H. Dukal, C. Klein, S. Schmitt, P. Gelss, U. Platzbecker, E. Balaian, A. Fabarius, H. Blum, T. J. Schulze, M. Meggendorfer, C. Haferlach, A. Trumpp, W.-K. Hofmann, H. Medyouf, D. Nowak
Published in: Blood, Issue 128/9, 2016, Page(s) 1246-1259, ISSN 0006-4971
DOI: 10.1182/blood-2015-11-679167

The microenvironment in human myeloid malignancies: emerging concepts and therapeutic implications

Author(s): Hind Medyouf
Published in: Blood, Issue 129/12, 2017, Page(s) 1617-1626, ISSN 0006-4971
DOI: 10.1182/blood-2016-11-696070

CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

Author(s): I Tirado-Gonzalez, E Czlonka, A Nevmerzhitskaya, D Soetopo, E Bergonzani, A Mahmoud, A Contreras, I Jeremias, U Platzbecker, J P Bourquin, U Kloz, F Van der Hoeven, H Medyouf
Published in: Leukemia, Issue 32/4, 2017, Page(s) 1049-1052, ISSN 0887-6924
DOI: 10.1038/leu.2017.346