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Modeling and treating retinal degenerative disease

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Publications

Noninvasive gene delivery to foveal cones for vision restoration

Author(s): Hanen Khabou, Marcela Garita-Hernandez, Antoine Chaffiol, Sacha Reichman, Céline Jaillard, Elena Brazhnikova, Stéphane Bertin, Valérie Forster, Mélissa Desrosiers, Céline Winckler, Olivier Goureau, Serge Picaud, Jens Duebel, José-Alain Sahel, Deniz Dalkara
Published in: JCI Insight, Issue 3/2, 2018, ISSN 2379-3708
DOI: 10.1172/jci.insight.96029

Optogenetic Light Sensors in Human Retinal Organoids

Author(s): Marcela Garita-Hernandez, Laure Guibbal, Lyes Toualbi, Fiona Routet, Antoine Chaffiol, Celine Winckler, Marylin Harinquet, Camille Robert, Stephane Fouquet, Sebastien Bellow, José-Alain Sahel, Olivier Goureau, Jens Duebel, Deniz Dalkara
Published in: Frontiers in Neuroscience, Issue 12, 2018, ISSN 1662-453X
DOI: 10.3389/fnins.2018.00789

Gene therapy for retinal dystrophy

Author(s): José Alain Sahel, Deniz Dalkara
Published in: Nature Medicine, Issue 25/2, 2019, Page(s) 198-199, ISSN 1078-8956
DOI: 10.1038/s41591-019-0346-1

Restoration of visual function by transplantation of optogenetically engineered photoreceptors

Author(s): Marcela Garita-Hernandez, Maruša Lampič, Antoine Chaffiol, Laure Guibbal, Fiona Routet, Tiago Santos-Ferreira, Sylvia Gasparini, Oliver Borsch, Giuliana Gagliardi, Sacha Reichman, Serge Picaud, José-Alain Sahel, Olivier Goureau, Marius Ader, Deniz Dalkara, Jens Duebel
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-12330-2

AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells

Author(s): Marcela Garita-Hernandez, Fiona Routet, Laure Guibbal, Hanen Khabou, Lyes Toualbi, Luisa Riancho, Sacha Reichman, Jens Duebel, Jose-Alain Sahel, Olivier Goureau, Deniz Dalkara
Published in: International Journal of Molecular Sciences, Issue 21/3, 2020, Page(s) 994, ISSN 1422-0067
DOI: 10.3390/ijms21030994

Vectors and Gene Delivery to the Retina

Author(s): Arthur Planul, Deniz Dalkara
Published in: Annual Review of Vision Science, Issue 3/1, 2017, Page(s) 121-140, ISSN 2374-4642
DOI: 10.1146/annurev-vision-102016-061413

Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery

Author(s): Mélissa Desrosiers, Deniz Dalkara
Published in: Retinal Gene Therapy, Issue 1715, 2018, Page(s) 225-238
DOI: 10.1007/978-1-4939-7522-8_16

AAV-Mediated Gene to Foveal Cones

Author(s): Stéphane Bertin, Elena Brazhnikova, Céline Jaillard, José-Alain Sahel, Deniz Dalkara
Published in: Photoswitching Proteins - Methods and Protocols, Issue 2173, 2020, Page(s) 101-112
DOI: 10.1007/978-1-0716-0755-8_6