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Simultaneous three dimensional multiphoton microscopy without mechanical depth scanning

Objective

Information in the nervous system is typically represented in activity patterns distributed across large populations of neurons in three dimensions, and there is a lot of current interest in the development of systems that can volumetrically image these patterns (or other distributed processes) in real-time. During our work towards imaging responses to artificial retinal stimulation we have developed a solution for remotely manipulating the illumination plane during temporal-focusing multiphoton imaging (a powerful bio-microscopy and photo-manipulation modality). This technique and its variations could provide unprecedented access into rapid 3D imaging at an exciting time for the neuroimaging field, where major initiatives for high-resolution brain activity mapping have been launched, and could potentially also be applied towards innovative approaches to micro-endoscopy and other applications.

Field of science

  • /natural sciences/biological sciences/neurobiology

Call for proposal

ERC-2014-PoC
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Funding Scheme

ERC-POC - Proof of Concept Grant

Host institution

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Address
Senate Building Technion City
32000 Haifa
Israel
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 150 000

Beneficiaries (1)

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel
EU contribution
€ 150 000
Address
Senate Building Technion City
32000 Haifa
Activity type
Higher or Secondary Education Establishments