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The next generation epigenetic medicine for inflammation

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Research dissemination

-portfolio of final dissemination and press releases -communication at scientific conferences -Publication of results ESRs

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Publications

A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn’s disease patients

Author(s): Andrew Y. F. Li Yim, Jessica R. de Bruyn, Nicolette W. Duijvis, Catriona Sharp, Enrico Ferrero, Wouter J. de Jonge, Manon E. Wildenberg, Marcel M. A. M. Mannens, Christianne J. Buskens, Geert R. D’Haens, Peter Henneman, Anje A. te Velde
Published in: PLOS ONE, Issue 13/12, 2018, Page(s) e0209656, ISSN 1932-6203
DOI: 10.1371/journal.pone.0209656

Myeloid Kdm6b deficiency results in advanced atherosclerosis

Author(s): Annette E. Neele, Marion J.J. Gijbels, Saskia van der Velden, Marten A. Hoeksema, Marieke C.S. Boshuizen, Koen H.M. Prange, Hung-Jen Chen, Jan Van den Bossche, Cindy P.P.A. van Roomen, Annelie Shami, Johannes H.M. Levels, Jeffrey Kroon, Tina Lucas, Stefanie Dimmeler, Esther Lutgens, Menno P.J. de Winther
Published in: Atherosclerosis, Issue 275, 2018, Page(s) 156-165, ISSN 0021-9150
DOI: 10.1016/j.atherosclerosis.2018.05.052

Peripheral blood methylation profiling of female Crohn’s disease patients

Author(s): Andrew Y. F. Li Yim, Nicolette W. Duijvis, Jing Zhao, Wouter J. de Jonge, Geert R. A. M. D’Haens, Marcel M. A. M. Mannens, Adri N. P. M. Mul, Anje A. te Velde, Peter Henneman
Published in: Clinical Epigenetics, Issue 8/1, 2016, ISSN 1868-7075
DOI: 10.1186/s13148-016-0230-5

Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Author(s): Vincent A. van der Mark, Mohammed Ghiboub, Casper Marsman, Jing Zhao, Remco van Dijk, Johan K. Hiralall, Kam S. Ho-Mok, Zoë Castricum, Wouter J. de Jonge, Ronald P. J. Oude Elferink, Coen C. Paulusma
Published in: Cellular and Molecular Life Sciences, Issue 74/4, 2017, Page(s) 715-730, ISSN 1420-682X
DOI: 10.1007/s00018-016-2360-5

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

Author(s): Jan Van den Bossche, Jeroen Baardman, Natasja A. Otto, Saskia van der Velden, Annette E. Neele, Susan M. van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C.S. Boshuizen, Mohamed Ahmed, Marten A. Hoeksema, Alex F. de Vos, Menno P.J. de Winther
Published in: Cell Reports, Issue 17/3, 2016, Page(s) 684-696, ISSN 2211-1247
DOI: 10.1016/j.celrep.2016.09.008

Neuroimmune Interactions in the Gut and Their Significance for Intestinal Immunity

Author(s): David J. Brinkman, Anne S. ten Hove, Margriet J. Vervoordeldonk, Misha D. Luyer, Wouter J. de Jonge
Published in: Cells, Issue 8/7, 2019, Page(s) 670, ISSN 2073-4409
DOI: 10.3390/cells8070670

Erratum to: Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Author(s): Vincent A. van der Mark, Mohammed Ghiboub, Casper Marsman, Jing Zhao, Remco van Dijk, Johan K. Hiralall, Kam S. Ho-Mok, Zoë Castricum, Wouter J. de Jonge, Ronald P. J. Oude Elferink, Coen C. Paulusma
Published in: Cellular and Molecular Life Sciences, Issue 74/7, 2017, Page(s) 1365-1365, ISSN 1420-682X
DOI: 10.1007/s00018-017-2475-3