The next generation epigenetic medicine for inflammation

Project Information

EPIMAC

Grant agreement ID: 641665

DOI 10.3030/641665

Project closed

EC signature date 4 December 2014

Start date 1 January 2015

End date 30 June 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 1 294 785,00

EU contribution € 1 294 785,00

Coordinated by

AMC MEDICAL RESEARCH BV
Netherlands

Deliverables

Documents, reports (2)

Management, administration and finance 5c

kickoff meeting

Management, administration and finance 5d

-Thesis of ESRs

Other (1)

Research dissemination

-portfolio of final dissemination and press releases -communication at scientific conferences -Publication of results ESRs

Publications

Peer reviewed articles (7)

A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn’s disease patients

Author(s): Andrew Y. F. Li Yim, Jessica R. de Bruyn, Nicolette W. Duijvis, Catriona Sharp, Enrico Ferrero, Wouter J. de Jonge, Manon E. Wildenberg, Marcel M. A. M. Mannens, Christianne J. Buskens, Geert R. D’Haens, Peter Henneman, Anje A. te Velde
Published in: PLOS ONE, Issue 13/12, 2018, Page(s) e0209656, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0209656

Myeloid Kdm6b deficiency results in advanced atherosclerosis

Author(s): Annette E. Neele, Marion J.J. Gijbels, Saskia van der Velden, Marten A. Hoeksema, Marieke C.S. Boshuizen, Koen H.M. Prange, Hung-Jen Chen, Jan Van den Bossche, Cindy P.P.A. van Roomen, Annelie Shami, Johannes H.M. Levels, Jeffrey Kroon, Tina Lucas, Stefanie Dimmeler, Esther Lutgens, Menno P.J. de Winther
Published in: Atherosclerosis, Issue 275, 2018, Page(s) 156-165, ISSN 0021-9150
Publisher: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2018.05.052

Peripheral blood methylation profiling of female Crohn’s disease patients

Author(s): Andrew Y. F. Li Yim, Nicolette W. Duijvis, Jing Zhao, Wouter J. de Jonge, Geert R. A. M. D’Haens, Marcel M. A. M. Mannens, Adri N. P. M. Mul, Anje A. te Velde, Peter Henneman
Published in: Clinical Epigenetics, Issue 8/1, 2016, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-016-0230-5

Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Author(s): Vincent A. van der Mark, Mohammed Ghiboub, Casper Marsman, Jing Zhao, Remco van Dijk, Johan K. Hiralall, Kam S. Ho-Mok, Zoë Castricum, Wouter J. de Jonge, Ronald P. J. Oude Elferink, Coen C. Paulusma
Published in: Cellular and Molecular Life Sciences, Issue 74/4, 2017, Page(s) 715-730, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-016-2360-5

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

Author(s): Jan Van den Bossche, Jeroen Baardman, Natasja A. Otto, Saskia van der Velden, Annette E. Neele, Susan M. van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C.S. Boshuizen, Mohamed Ahmed, Marten A. Hoeksema, Alex F. de Vos, Menno P.J. de Winther
Published in: Cell Reports, Issue 17/3, 2016, Page(s) 684-696, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2016.09.008

Neuroimmune Interactions in the Gut and Their Significance for Intestinal Immunity

Author(s): David J. Brinkman, Anne S. ten Hove, Margriet J. Vervoordeldonk, Misha D. Luyer, Wouter J. de Jonge
Published in: Cells, Issue 8/7, 2019, Page(s) 670, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8070670

Erratum to: Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

Author(s): Vincent A. van der Mark, Mohammed Ghiboub, Casper Marsman, Jing Zhao, Remco van Dijk, Johan K. Hiralall, Kam S. Ho-Mok, Zoë Castricum, Wouter J. de Jonge, Ronald P. J. Oude Elferink, Coen C. Paulusma
Published in: Cellular and Molecular Life Sciences, Issue 74/7, 2017, Page(s) 1365-1365, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-017-2475-3