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RNA-based technologies for single-cell metabolite analysis

Objective

Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation through exploiting exciting opportunities emerging from the RNA field. Such synergy potential between the metabolism and RNA research fields has until today not been exploited, because they are separated from each other in Europe and worldwide. Through consequently missing research training programs we thus lack experts with combined knowledge in metabolism and RNA. The aim of the MetaRNA proposal is therefore to establish a European Training Network (ETN) that educates specialists for academia and industry - fully trained at the interface of these two fields - in the development and application of RNA-based sensors to investigate metabolism at the single-cell level, to apply these tools for novel biotechnological applications and to provide a framework for their future use in diagnostics and therapeutics. In MetaRNA, eight research groups from the metabolic and RNA fields and six partners from the private sector join forces to create a platform of mobility and training to 15 early-stage researchers (ESRs), by means of customized research projects, exchange of knowhow among researchers and partners, attendance to specialized courses, workshops and conferences, as well as training in complementary skills.

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
Net EU contribution
€ 510 748,56
Address
Broerstraat 5
9712CP Groningen
Netherlands

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Region
Noord-Nederland Groningen Overig Groningen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (10)

UNITED KINGDOM RESEARCH AND INNOVATION

Participation ended

United Kingdom
Net EU contribution
€ 22 773,99
Address
Polaris House North Star Avenue
SN2 1FL Swindon

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Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon
Activity type
Research Organisations
Non-EU contribution
€ 0,00
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN
Germany
Net EU contribution
€ 498 432,96
Address
Regina Pacis Weg 3
53113 Bonn

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Region
Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
DANMARKS TEKNISKE UNIVERSITET
Denmark
Net EU contribution
€ 580 163,76
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby

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Region
Danmark Hovedstaden Københavns omegn
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE UNIVERSITY OF WARWICK
United Kingdom
Net EU contribution
€ 273 287,88
Address
Kirby Corner Road - University House
CV4 8UW Coventry

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Region
West Midlands (England) West Midlands Coventry
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
TECHNISCHE UNIVERSITAT DARMSTADT
Germany
Net EU contribution
€ 498 432,96
Address
Karolinenplatz 5
64289 Darmstadt

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Region
Darmstadt Darmstadt, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 525 751,20
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
KOBENHAVNS UNIVERSITET
Denmark
Net EU contribution
€ 290 081,88
Address
Norregade 10
1165 Kobenhavn

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
BIOSYNTIA APS
Denmark
Net EU contribution
€ 290 081,88
Address
Kogle Alle 6
2970 Horsholm

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Danmark Hovedstaden Nordsjælland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
DSM FOOD SPECIALTIES BV
Netherlands
Net EU contribution
€ 255 374,28
Address
Alexander Fleminglaan 1
2613 AX Delft

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Region
West-Nederland Zuid-Holland Delft en Westland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom
Net EU contribution
€ 250 513,89
Address
1 Midland Road
NW1 1AT London

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Region
London Inner London — West Camden and City of London
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Partners (4)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

APTAIT GMBH
Germany
Net EU contribution
€ 0,00
Address
Leonhardistrasse 2e
86911 Diessen

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bayern Oberbayern Landsberg am Lech
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

EVOLVA AG
Switzerland
Net EU contribution
€ 0,00
Address
Duggingerstrasse 23
4153 Reinach

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CENTRE TECHNOLOGIQUE NOUVELLE-AQUITAINE COMPOSITES & MATERIAUX AVANCES
France
Net EU contribution
€ 0,00
Address
Batiment Cheminnov Enscbp Av Pey Berland 16
33600 Pessac

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nouvelle-Aquitaine Aquitaine Gironde
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

TPP Global Development Limited
United Kingdom
Net EU contribution
€ 0,00
Address
Edinburgh Bioquarter
EH16 4UX Edinburgh

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Region
Eastern Scotland Edinburgh
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00