Objective
Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour.
The Research Training Network on Integrated Component Cycling in Epithelial Cell Motility (InCeM) aims to endow up-and-coming researchers with exactly these competencies. They will be able to develop and apply innovative devices for microscopic recording, image processing techniques, data analysis tools and modelling procedures for mechanistic understanding of cell migration. InCeM will focus on epithelial cells, since inducing motility in this cell type is clinically relevant for wound healing and cancer invasion. The ultimate goal is to control and manipulate cell migration for clinical applications. A dedicated multidisciplinary team of 11 beneficiaries from universities (4), research institutions (4) and industry (3), based in 5 European countries and Israel, together with 17 associated partners from the public and private sector, will train 15 Early Stage Researchers (ESRs) to use the relevant technologies and sciences and will offer business training to prepare them for successful careers in both academic and non-academic environments.
Fields of science
- natural sciencesmathematicsapplied mathematicsnumerical analysis
- natural sciencesmathematicspure mathematicsmathematical analysisdifferential equationspartial differential equations
- natural sciencesbiological sciencescell biologycell polarity
- natural sciencescomputer and information sciencesdata science
- natural sciencesmathematicsapplied mathematicsmathematical model
Programme(s)
Call for proposal
H2020-MSCA-ITN-2014
See other projects for this call
Funding Scheme
MSCA-ITN-ETN - European Training Networks
Coordinator
52074 Aachen
Germany
Participants (11)
52428 Julich
7610001 Rehovot
45141 Essen
4232 Hagenberg
69978 Tel Aviv
BN1 9RH Brighton
Participation ended
1011 JV Amsterdam
BT12 7AL Belfast
82152 Planegg Martinsried
75183 Uppsala
1066 CX Amsterdam
Partners (17)
8092 Zuerich
751 05 Uppsala
Uppsala
Linz
82152 Planegg Martinsried
07745 Jena
Münster
R3T 2N2 Manitoba
5349 AB Oss
80797 Munchen
3584 BL Utrecht
Cambridge
53113 Bonn
80539 Munchen
40789 Monheim
3584 CS Utrecht
1020 Vienna