Objective
Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour.
The Research Training Network on Integrated Component Cycling in Epithelial Cell Motility (InCeM) aims to endow up-and-coming researchers with exactly these competencies. They will be able to develop and apply innovative devices for microscopic recording, image processing techniques, data analysis tools and modelling procedures for mechanistic understanding of cell migration. InCeM will focus on epithelial cells, since inducing motility in this cell type is clinically relevant for wound healing and cancer invasion. The ultimate goal is to control and manipulate cell migration for clinical applications. A dedicated multidisciplinary team of 11 beneficiaries from universities (4), research institutions (4) and industry (3), based in 5 European countries and Israel, together with 17 associated partners from the public and private sector, will train 15 Early Stage Researchers (ESRs) to use the relevant technologies and sciences and will offer business training to prepare them for successful careers in both academic and non-academic environments.
Fields of science
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- natural sciencesbiological sciencescell biologycell polarity
- natural sciencesmathematicspure mathematicsmathematical analysisdifferential equationspartial differential equations
- natural sciencesmathematicsapplied mathematicsnumerical analysis
- natural sciencesmathematicsapplied mathematicsmathematical model
Programme(s)
Funding Scheme
MSCA-ITN-ETN - European Training NetworksCoordinator
52074 Aachen
Germany
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Participants (11)
52428 Julich
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7610001 Rehovot
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45141 Essen
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4232 Hagenberg
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69978 Tel Aviv
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BN1 9RH Brighton
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Participation ended
1011 JV Amsterdam
BT12 7AL Belfast
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
82152 Planegg Martinsried
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
75183 Uppsala
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1066 CX Amsterdam
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Partners (17)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
8092 Zuerich
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751 05 Uppsala
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Uppsala
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Linz
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82152 Planegg Martinsried
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
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07745 Jena
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Münster
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R3T 2N2 Manitoba
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5349 AB Oss
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80797 Munchen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
2289 DC Rijswijk
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
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Cambridge
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53113 Bonn
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80539 Munchen
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
40789 Monheim
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3584 CS Utrecht
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1020 Vienna
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.