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Research Training Network on Integrated Component Cycling in Epithelial Cell Motility



• Workshop 6: • evaluating need and options for continuation of training and research in the field of cell migration • presenting results to the scientific community and press


• workshop 5: • discussing results with international experts

PhD theses

• submitting and defending PhD theses

Communication 1

• communicating results in publications and at international meetings

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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

Author(s): Melanie Graessl, Johannes Koch, Abram Calderon, Dominic Kamps, Soumya Banerjee, Tomáš Mazel, Nina Schulze, Jana Kathrin Jungkurth, Rutuja Patwardhan, Djamschid Solouk, Nico Hampe, Bernd Hoffmann, Leif Dehmelt, Perihan Nalbant
Published in: The Journal of Cell Biology, Issue 216/12, 2017, Page(s) 4271-4285, ISSN 0021-9525
DOI: 10.1083/jcb.201706052

A robust and efficient adaptive multigrid solver for the optimal control of phase field formulations of geometric evolution laws.

Author(s): Yang, F, Venkataraman, C, Styles, V and Madzvamuse, A
Published in: Communications in Computational Physics, Issue 2/17, 2016, Page(s) 65-92, ISSN 1815-2406
DOI: 10.4208/cicp.240715.080716a

Projected finite elements for systems of reaction-diffusion equations on evolving spheroidal surfaces

Author(s): Tuncer, Necibe and Madzvamuse, Anotida
Published in: Communications in Computational Physics, Issue 2/17, 2017, Page(s) 718-747, ISSN 1815-2406
DOI: 10.4208/cicp.OA-2016-0029

A note on how to develop interdisciplinary collaborations between experimentalists and theoreticians

Author(s): Anotida Madzvamuse, Sharon R. Lubkin
Published in: Interface Focus, Issue 6/5, 2016, Page(s) 20160069, ISSN 2042-8898
DOI: 10.1098/rsfs.2016.0069

Effects of Plectin Depletion on Keratin Network Dynamics and Organization

Author(s): Marcin Moch, Reinhard Windoffer, Nicole Schwarz, Raphaela Pohl, Andreas Omenzetter, Uwe Schnakenberg, Fabian Herb, Kraisorn Chaisaowong, Dorit Merhof, Lena Ramms, Gloria Fabris, Bernd Hoffmann, Rudolf Merkel, Rudolf E. Leube
Published in: PLOS ONE, Issue 11/3, 2016, Page(s) e0149106, ISSN 1932-6203
DOI: 10.1371/journal.pone.0149106

The bulk-surface finite element method for reaction–diffusion systems on stationary volumes

Author(s): Anotida Madzvamuse, Andy H.W. Chung
Published in: Finite Elements in Analysis and Design, Issue 108, 2016, Page(s) 9-21, ISSN 0168-874X
DOI: 10.1016/j.finel.2015.09.002

Stability analysis of reaction-diffusion models on evolving domains: The effects of cross-diffusion

Author(s): Anotida Madzvamuse, Hussaini Ndakwo, Raquel Barreira
Published in: Discrete and Continuous Dynamical Systems, Issue 36/4, 2016, Page(s) 2133-2170, ISSN 1078-0947
DOI: 10.3934/dcds.2016.36.2133

A coupled bulk-surface model for cell polarisation

Author(s): D. Cusseddu, L. Edelstein-Keshet, J.A. Mackenzie, S. Portet, A. Madzvamuse
Published in: Journal of Theoretical Biology, 2018, ISSN 0022-5193
DOI: 10.1016/j.jtbi.2018.09.008

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells

Author(s): D. J. Huels, L. Bruens, M. C. Hodder, P. Cammareri, A. D. Campbell, R. A. Ridgway, D. M. Gay, M. Solar-Abboud, W. J. Faller, C. Nixon, L. B. Zeiger, M. E. McLaughlin, E. Morrissey, D. J. Winton, H. J. Snippert, J. van Rheenen, O. J. Sansom
Published in: Nature Communications, Issue 9/1, 2018, Page(s) Article number 1132, ISSN 2041-1723
DOI: 10.1038/s41467-018-03426-2

Potential impact of invasive surgical procedures on primary tumor growth and metastasis

Author(s): Maria Alieva, Jacco van Rheenen, Marike L. D. Broekman
Published in: Clinical & Experimental Metastasis, Issue 35/4, 2018, Page(s) 319-331, ISSN 0262-0898
DOI: 10.1007/s10585-018-9896-8

Domain-growth-induced patterning for reaction-diffusion systems with linear cross-diffusion

Author(s): Anotida Madzvamuse, Raquel Barreira
Published in: Discrete & Continuous Dynamical Systems - B, Issue 22/11, 2017, Page(s) 1-27, ISSN 1531-3492
DOI: 10.3934/dcdsb.2018163

Lumped finite elements for reaction–cross-diffusion systems on stationary surfaces

Author(s): Massimo Frittelli, Anotida Madzvamuse, Ivonne Sgura, Chandrasekhar Venkataraman
Published in: Computers & Mathematics with Applications, Issue 74/12, 2017, Page(s) 3008-3023, ISSN 0898-1221
DOI: 10.1016/j.camwa.2017.07.044

Intracellular Motility of Intermediate Filaments

Author(s): Rudolf E. Leube, Marcin Moch, Reinhard Windoffer
Published in: Cold Spring Harbor Perspectives in Biology, Issue 9/6, 2017, Page(s) a021980, ISSN 1943-0264
DOI: 10.1101/cshperspect.a021980

Domain-Dependent Stability Analysis of a Reaction–Diffusion Model on Compact Circular Geometries

Author(s): Wakil Sarfaraz, Anotida Madzvamuse
Published in: International Journal of Bifurcation and Chaos, Issue 28/08, 2018, Page(s) 1830024, ISSN 0218-1274
DOI: 10.1142/s0218127418300240

Parameter identification through mode isolation for reaction–diffusion systems on arbitrary geometries

Author(s): Laura Murphy, Chandrasekhar Venkataraman, Anotida Madzvamuse
Published in: International Journal of Biomathematics, Issue 11/04, 2018, Page(s) 1850053, ISSN 1793-5245
DOI: 10.1142/s1793524518500535

A mathematical understanding of how cytoplasmic dynein walks on microtubules

Author(s): L. Trott, M. Hafezparast, A. Madzvamuse
Published in: Royal Society Open Science, Issue 5/8, 2018, Page(s) 171568, ISSN 2054-5703
DOI: 10.1098/rsos.171568

Bayesian Parameter Identification for Turing Systems on Stationary and Evolving Domains

Author(s): Eduard Campillo-Funollet, Chandrasekhar Venkataraman, Anotida Madzvamuse
Published in: Bulletin of Mathematical Biology, 2018, Page(s) 1-24, ISSN 0092-8240
DOI: 10.1007/s11538-018-0518-z

Numerical Preservation of Velocity Induced Invariant Regions for Reaction–Diffusion Systems on Evolving Surfaces

Author(s): Massimo Frittelli, Anotida Madzvamuse, Ivonne Sgura, Chandrasekhar Venkataraman
Published in: Journal of Scientific Computing, Issue 77/2, 2018, Page(s) 971-1000, ISSN 0885-7474
DOI: 10.1007/s10915-018-0741-7

A Model for Selection of Eyespots on Butterfly Wings

Author(s): Toshio Sekimura, Chandrasekhar Venkataraman, Anotida Madzvamuse
Published in: PLOS ONE, Issue 10/11, 2015, Page(s) e0141434, ISSN 1932-6203
DOI: 10.1371/journal.pone.0141434

Classification of parameter spaces for a reaction-diffusion model on stationary domains

Author(s): Wakil Sarfaraz, Anotida Madzvamuse
Published in: Chaos, Solitons & Fractals, Issue 103, 2017, Page(s) 33-51, ISSN 0960-0779
DOI: 10.1016/j.chaos.2017.05.032

Nanoscale Topography and Poroelastic Properties of Model Tissue Breast Gland Basement Membranes

Author(s): Gloria Fabris, Alessandro Lucantonio, Nico Hampe, Erik Noetzel, Bernd Hoffmann, Antonio DeSimone, Rudolf Merkel
Published in: Biophysical Journal, Issue 115/9, 2018, Page(s) 1770-1782, ISSN 0006-3495
DOI: 10.1016/j.bpj.2018.09.020

Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function

Author(s): Nicole Schwarz, Rudolf Leube
Published in: Cells, Issue 5/3, 2016, Page(s) 30, ISSN 2073-4409
DOI: 10.3390/cells5030030

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

Author(s): Sander C Steenbeek, Thang V Pham, Joep de Ligt, Anoek Zomer, Jaco C Knol, Sander R Piersma, Tim Schelfhorst, Rick Huisjes, Raymond M Schiffelers, Edwin Cuppen, Connie R Jimenez, Jacco van Rheenen
Published in: The EMBO Journal, Issue 37/15, 2018, Page(s) e98357, ISSN 0261-4189
DOI: 10.15252/embj.201798357

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

Author(s): Arianna Fumagalli, Saskia J E Suijkerbuijk, Harry Begthel, Evelyne Beerling, Koen C Oost, Hugo J Snippert, Jacco van Rheenen, Jarno Drost
Published in: Nature Protocols, Issue 13/2, 2018, Page(s) 235-247, ISSN 1754-2189
DOI: 10.1038/nprot.2017.137

Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells

Author(s): Scott Rata, Maria F. Suarez Peredo Rodriguez, Stephy Joseph, Nisha Peter, Fabio Echegaray Iturra, Fengwei Yang, Anotida Madzvamuse, Jan G. Ruppert, Kumiko Samejima, Melpomeni Platani, Monica Alvarez-Fernandez, Marcos Malumbres, William C. Earnshaw, Bela Novak, Helfrid Hochegger
Published in: Current Biology, Issue 28/23, 2018, Page(s) 3824-3832.e6, ISSN 0960-9822
DOI: 10.1016/j.cub.2018.09.059

A Modular and Affordable Time-Lapse Imaging and Incubation System Based on 3D-Printed Parts, a Smartphone, and Off-The-Shelf Electronics

Author(s): Rodrigo Hernández Vera, Emil Schwan, Nikos Fatsis-Kavalopoulos, Johan Kreuger
Published in: PLOS ONE, Issue 11/12, 2016, Page(s) e0167583, ISSN 1932-6203
DOI: 10.1371/journal.pone.0167583

Analysis and Simulations of Coupled Bulk-surface Reaction-Diffusion Systems on Exponentially Evolving Volumes

Author(s): A. Madzvamuse, A. H. Chung
Published in: Mathematical Modelling of Natural Phenomena, Issue 11/5, 2016, Page(s) 4-32, ISSN 1760-6101
DOI: 10.1051/mmnp/201611502

A computational framework for particle and whole cell tracking applied to a real biological dataset

Author(s): Feng Wei Yang, Chandrasekhar Venkataraman, Vanessa Styles, Verena Kuttenberger, Elias Horn, Zeno von Guttenberg, Anotida Madzvamuse
Published in: Journal of Biomechanics, Issue February 2016, 2016, ISSN 0021-9290
DOI: 10.1016/j.jbiomech.2016.02.008

Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior

Author(s): Maria Alieva, Andreia S. Margarido, Tamara Wieles, Erik R. Abels, Burcin Colak, Carla Boquetale, Herke Jan Noordmans, Tom J. Snijders, Marike L. Broekman, Jacco van Rheenen
Published in: Scientific Reports, Issue 7/1, 2017, Page(s) 7529, ISSN 2045-2322
DOI: 10.1038/s41598-017-07660-4

From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells

Author(s): Saskia J.E. Suijkerbuijk, Jacco van Rheenen
Published in: Developmental Biology, Issue 428/2, 2017, Page(s) 328-337, ISSN 0012-1606
DOI: 10.1016/j.ydbio.2017.04.015


Author(s): Galiya Sakaeva, Dmytro Kotsur, Kritika Sahni, Georg Dreissen, Julian Mattes, Bernd Hoffmann, Rudolf Merkel
Published in: 3rd International Symposium on Mechanobiology, Issue 2017, 2017


Author(s): Kritika Sahni, Dmytro Kotsur, Georg Dreissen, Dr. Julian Mattes, Dr. Bernd Hoffmann, Prof. Dr. Rudolf Merkel, Galiya Sakaeva
Published in: 3rd International Symposium on Mechanobiology, Issue 2017, 2017

Analysis of variable-order interacting multiple model algorithms for cell tracking

Author(s): K. Lomanov, J. Martinez del Rincon, P. Miller & H. Gribben
Published in: Proceedings of the 18th Irish Machine Vision and Image Processing conference, Issue Yearly, 2016, Page(s) 35-42

Cross-diffusion in reaction-diffusion models: analysis, numerics and applications

Author(s): Anotida Madzvamuse, Raquel Barreira, Alf Gerisch
Published in: Progress in Industrial Mathematics at ECMI 2016, Issue 26, 2018, Page(s) 385-392
DOI: 10.1007/978-3-319-63082-3_61

LAP-based tracking for focal adhesions

Author(s): Katerina Lomanov, Jesus Martinez del Rincon, Paul Miller, Hugh Gribben
Published in: Irish Machine Vision and Image Processing Conference Proceedings 2018: Proceedings, Issue Yearly, 2018

An algorithm for individual intermediate filament tracking

Author(s): Dmytro Kotsur, Roman Yakobenchuk, Rudolf Leube, Reinhard Windoffer, Julian Mattes

Active contour models for individual keratin filament tracking

Author(s): Dmytro Kotsur, Rudolf Leube, Reinhard Windoffer, Julian Mattes
Published in: Proceedings of the OAGM&ARW Joint Workshop: Vision, Automation and Robotics, Issue May, 2017, 2017, Page(s) 109-110
DOI: 10.3217/978-3-85125-524-9-19

CSI-Krebs: So findet man die passende Therapie

Author(s): Martin Rümmele
Published in: medianet Dossier - health economy, Issue 10/2018, 2018, Page(s) 4-5

Impact of keratin network regulation on migrating cells

Author(s): Anne PORA
Published in: 2018