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The Development of Medium- and Large-Scale Sustainable Manufacturing Process Platforms for Clinically Compliant Solid Core Nanopharmaceuticals


Final project report

Publication of the project’s achieved final results and exploitation plan.

Updated dissemination and exploitation plan

An updated version of the plan describing progress to date and future planned D and E plans.

Outline dissemination plan

A plan detailing how the consortium intends to share the non confidential aspects of the project to the wider community. This will include methods of dissemination.

NANOFACTURING logo, brochure and leaflets

NANOFACTURING logo developed. Publication of project description and its aims in a leaflet/brochure form.

Launch of NANOFACTURING Website

Launch of the website which will function as the dissemination portal for this project.

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Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

Author(s): Kristof Zarschler, Louise Rocks, Nadia Licciardello, Luca Boselli, Ester Polo, Karina Pombo Garcia, Luisa De Cola, Holger Stephan, Kenneth A. Dawson
Published in: Nanomedicine: Nanotechnology, Biology and Medicine, 12/6, 2016, Page(s) 1663-1701, ISSN 1549-9634
Publisher: Elsevier BV
DOI: 10.1016/j.nano.2016.02.019

Synthesis, characterization and programmable toxicity of iron oxide nanoparticles conjugated with d -amino acid oxidase

Author(s): Riccardo Balzaretti, Fabian Meder, Marco P. Monopoli, Luca Boselli, Ilaria Armenia, Loredano Pollegioni, Giovanni Bernardini, Rosalba Gornati
Published in: RSC Advances, 7/3, 2017, Page(s) 1439-1442, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/c6ra25349k

Graphene Nanoflake Uptake Mediated by Scavenger Receptors

Author(s): Fatima Alnasser, Valentina Castagnola, Luca Boselli, Margarita Esquivel-Gaon, Esen Efeoglu, Jennifer McIntyre, Hugh J. Byrne, Kenneth A. Dawson
Published in: Nano Letters, 19/2, 2019, Page(s) 1260-1268, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.8b04820

Regimes of Biomolecular Ultrasmall Nanoparticle Interactions

Author(s): Luca Boselli, Ester Polo, Valentina Castagnola, Kenneth A. Dawson
Published in: Angewandte Chemie, 129/15, 2017, Page(s) 4279-4282, ISSN 0044-8249
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.201700343

Towards a classification strategy for complex nanostructures

Author(s): V. Castagnola, J. Cookman, J. M. de Araújo, E. Polo, Q. Cai, C. P. Silveira, Ž. Krpetić, Y. Yan, L. Boselli, K. A. Dawson
Published in: Nanoscale Horizons, 2/4, 2017, Page(s) 187-198, ISSN 2055-6756
Publisher: RSC
DOI: 10.1039/C6NH00219F

Biological recognition of graphene nanoflakes

Author(s): V. Castagnola, W. Zhao, L. Boselli, M. C. Lo Giudice, F. Meder, E. Polo, K. R. Paton, C. Backes, J. N. Coleman, K. A. Dawson
Published in: Nature Communications, 9/1, 2018, Page(s) 1577 (2018), ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-04009-x

Influence of Size and Shape on the Anatomical Distribution of Endotoxin-Free Gold Nanoparticles

Author(s): Laura Talamini, Martina B. Violatto, Qi Cai, Marco P. Monopoli, Karsten Kantner, Željka Krpetić, André Perez-Potti, Jennifer Cookman, David Garry, Camila P. Silveira, Luca Boselli, Beatriz Pelaz, Tommaso Serchi, Sébastien Cambier, Arno C. Gutleb, Neus Feliu, Yan Yan, Mario Salmona, Wolfgang J. Parak, Kenneth A. Dawson, Paolo Bigini
Published in: ACS Nano, 11/6, 2017, Page(s) 5519-5529, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.7b00497

Characterization of Ligand Shell for Mixed-Ligand Coated Gold Nanoparticles

Author(s): Quy Ong, Zhi Luo, Francesco Stellacci
Published in: Accounts of Chemical Research, 50/8, 2017, Page(s) 1911-1919, ISSN 0001-4842
Publisher: American Chemical Society
DOI: 10.1021/acs.accounts.7b00165

A centrifugation-based physicochemical characterization method for the interaction between proteins and nanoparticles

Author(s): Ahmet Bekdemir, Francesco Stellacci
Published in: Nature Communications, 7/1, 2016, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/ncomms13121

Evolution of the Ligand Shell Morphology during Ligand Exchange Reactions on Gold Nanoparticles

Author(s): Zhi Luo, Jing Hou, Laure Menin, Quy Khac Ong, Francesco Stellacci
Published in: Angewandte Chemie International Edition, 56/43, 2017, Page(s) 13521-13525, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201708190