Synthetic platforms for ad libitum remodelling of yeast central metabolism

Project Information

AdLibYeast

Grant agreement ID: 648141

DOI

10.3030/648141

Project closed

EC signature date 20 May 2015

Start date 1 September 2015

End date 31 August 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 149 717,50

EU contribution

€ 2 149 717,50

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

The genetic makeup and expression of the glycolytic and fermentative pathways are highly conserved within the Saccharomyces genus

Author(s): Francine J. Boonekamp, Sofia Dashko, Marcel van den Broek, Thies Gehrmann, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: Frontiers in Genetics, 2018, ISSN 1664-8021
Publisher: Frontiers Media

Synthetic chromosomes as new tools for large scale engineering of metabolism

Author(s): Eline Postma, Else Jasmijn Hassing, Venda Mangkusaputra, Jordi Geelhoed, Pilar de la Torre, Marcel van den Broek, Cristiaan Mooiman, Martin Pabst, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: Metabolic Engineering, 2021, ISSN 1096-7176
Publisher: Academic Press
DOI: 10.1101/2021.10.04.462994

A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae

Author(s): Eline Postma, Sofia Dashko, Lucas van Breemen, Shannara Taylor Parkins, Marcel van den Broek, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: Nucleic Acids Research, 2021, ISSN 1362-4962
Publisher: Oxford University Press

Pathway swapping: Toward modular engineering of essential cellular processes

Author(s): Niels G. Kuijpers, Daniel Solis-Escalante, Marijke A.H. Luttik, Markus M.M. Bisschops, Francine J. Boonekamp, Marcel van den Broek, Jack T Pronk, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: Proceeding of the National Academy of Science USA, 2016, ISSN 1091-6490
Publisher: National Academy of Sciences of the United States of America

Top-down, knowledge-based genetic reduction of yeast central carbon metabolism

Author(s): Eline Postma, Lucas Couwenberg, Roderick van Roosmalen, Jordi Geelhoed, Philip de Groot, Pascale Daran-Lapujade
Published in: mBio, 2021, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1101/2021.08.24.457526

A toolkit for rapid CRISPR-SpCas9 assisted construction of hexose-transport-deficient Saccharomyces cerevisiae strains

Author(s): Melanie Wijsman, Michał A Świat, Wesley L Marques, Johanna K Hettinga, Marcel van den Broek, Pilar de la Torre Cortés, Robert Mans, Jack T Pronk, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: FEMS Yeast Research, 2018, ISSN 1567-1364
Publisher: Oxford University Press
DOI: 10.1093/femsyr/foy107

FnCpf1: a novel and efficient genome editing tool for Saccharomyces cerevisiae

Author(s): Michal A. Świat, Sofia Dashko, Maxime den Ridder, Melanie Wijsman, John van der Oost, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: Nucleic Acids Research, Issue 45/21, 2017, Page(s) 12585-12598, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx1007

The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources

Author(s): Gemma Perez-Samper, Bram Cerulus, Abbas Jariani, Lieselotte Vermeersch, Nuria Barrajón Simancas, Markus M. M. Bisschops, Joost van den Brink, Daniel Solis-Escalante, Brigida Gallone, Dries De Maeyer, Elise van Bael, Tom Wenseleers, Jan Michiels, Kathleen Marchal, Pascale Daran-Lapujade, Kevin J. Verstrepen
Published in: mBio, Issue 9/5, 2018, ISSN 2150-7511
Publisher: ASM
DOI: 10.1128/mBio.01331-18

Design and experimental evaluation of a minimal, innocuous watermarking strategy to distinguish near-identical DNA and RNA sequences

Author(s): Francine J. Boonekamp, Sofia Dashko, Donna Duiker, Thies Gehrmann, Marcel van den Broek, Maxime den Ridder, Martin Pabst, Vincent Robert, Thomas Abeel, Eline Postma, Jean-Marc Daran, Pascale Daran-Lapujade
Published in: ACS Synthetic Biology, 2020, ISSN 2161-5063
Publisher: American Chemical Society

Thesis and dissertations (2)

Modular engineering of synthetic glycolytic pathways in Saccharomyces cerevisiae

Author(s): Francine J. Boonekamp
Published in: 2021
Publisher: Delft University of Technology

Single-step in vivo assembly of synthetic chromosomes with a modular design for engineering yeast metabolism

Author(s): Eline Postma
Published in: 2021
Publisher: Delft University of Technology

Other (1)

A yeast with muscle doesn’t run faster: full humanization of the glycolytic pathway in Saccharomyces cerevisiae.

Author(s): Francine J. Boonekamp, Ewout Knibbe, Marcel Vieira-Lara, Melanie Wijsman, Marijke Luttik, Karin van Eunen, Maxime den Ridder, Renier Bron, Anna Almonacid Suarez, Pieter van Rijn, J Wolters, Martin Pabst, Jean-Marc Daran, Barbara Bakker, Pascale Daran-Lapujade
Published in: BioRxiv, 2021
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.09.28.462164