How the Brain Learns to Forget - The Neural Signature of Fear Memory Erasure

Project Information

WipeOutFear

Grant agreement ID: 648176

DOI 10.3030/648176

Project closed

EC signature date 17 August 2015

Start date 1 September 2015

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (24)

Trait anxiety is associated with reduced typicality asymmetry in fear generalization

Author(s): Alex H.K. Wong, Tom Beckers
Published in: Behaviour Research and Therapy, Issue 138, 2021, Page(s) 103802, ISSN 0005-7967
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.brat.2021.103802

Preventing the return of fear in humans using reconsolidation update mechanisms: A verification report of Schiller et al. (2010)

Author(s): Anastasia Chalkia, Lukas Van Oudenhove, Tom Beckers
Published in: Cortex, Issue 129, 2020, Page(s) 510-525, ISSN 0010-9452
Publisher: Masson Publishing
DOI: 10.1016/j.cortex.2020.03.031

Apparent reconsolidation interference without generalized amnesia

Author(s): Joaquín M. Alfei, Hérnan De Gruy, Dimitri De Bundel, Laura Luyten, Tom Beckers
Published in: Progress in Neuro-Psychopharmacology and Biological Psychiatry, Issue 108, 2021, Page(s) 110161, ISSN 0278-5846
Publisher: Elsevier BV
DOI: 10.1016/j.pnpbp.2020.110161

c-Fos expression following context conditioning and deep brain stimulation in the bed nucleus of the stria terminalis in rats

Author(s): Kelly Luyck, Isabelle Scheyltjens, Bart Nuttin, Lutgarde Arckens, Laura Luyten
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-77603-z

Reactivation-Dependent Amnesia for Contextual Fear Memories: Evidence for Publication Bias

Author(s): Natalie Schroyens, Eric L. Sigwald, Wim Van Den Noortgate, Tom Beckers, Laura Luyten
Published in: eneuro, Issue 8/1, 2021, Page(s) ENEURO.0108-20.2020, ISSN 2373-2822
Publisher: Society for Neuroscience
DOI: 10.1523/eneuro.0108-20.2020

No persistent attenuation of fear memories in humans: A registered replication of the reactivation-extinction effect

Author(s): Anastasia Chalkia, Natalie Schroyens, Lu Leng, Niels Vanhasbroeck, Ann-Kathrin Zenses, Lukas Van Oudenhove, Tom Beckers
Published in: Cortex, Issue 129, 2020, Page(s) 496-509, ISSN 0010-9452
Publisher: Masson Publishing
DOI: 10.1016/j.cortex.2020.04.017

Lack of drug-induced post-retrieval amnesia for auditory fear memories in rats

Author(s): Laura Luyten, Anna Elisabeth Schnell, Natalie Schroyens, Tom Beckers
Published in: BMC Biology, Issue 19/1, 2021, Page(s) 17, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-021-00957-x

Failures to replicate blocking are surprising and informative—Reply to Soto (2018).

Author(s): Elisa Maes, Angelos-Miltiadis Krypotos, Yannick Boddez, Joaquín Matías Alfei Palloni, Rudi D'Hooge, Jan De Houwer, Tom Beckers
Published in: Journal of Experimental Psychology: General, Issue 147/4, 2018, Page(s) 603-610, ISSN 0096-3445
Publisher: American Psychological Association
DOI: 10.1037/xge0000413

A comparison of behavioral and pharmacological interventions to attenuate reactivated fear memories

Author(s): Roque I. Ferrer Monti, Joaquín M. Alfei, Matías Mugnaini, Adrián M. Bueno, Tom Beckers, Gonzalo P. Urcelay, Victor A. Molina
Published in: Learning & Memory, Issue 24/8, 2017, Page(s) 369-374, ISSN 1549-5485
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/lm.045385.117

A preregistered, direct replication attempt of the retrieval-extinction effect in cued fear conditioning in rats

Author(s): Laura Luyten, Tom Beckers
Published in: Neurobiology of Learning and Memory, Issue 144, 2017, Page(s) 208-215, ISSN 1074-7427
Publisher: Academic Press
DOI: 10.1016/j.nlm.2017.07.014

Distinct Activity Patterns of the Human Bed Nucleus of the Stria Terminalis and Amygdala during Fear Learning

Author(s): Kelly Luyck, Travis D. Goode, Haemy Lee Masson, Laura Luyten
Published in: Neuropsychology Review, 2018, ISSN 1040-7308
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11065-018-9383-7

Post-weaning housing conditions influence freezing during contextual fear conditioning in adult rats

Author(s): Natalie Schroyens, Crhistian Luis Bender, Joaquín Matias Alfei, Victor Alejandro Molina, Laura Luyten, Tom Beckers
Published in: Behavioural Brain Research, Issue 359, 2019, Page(s) 172-180, ISSN 0166-4328
Publisher: Elsevier BV
DOI: 10.1016/j.bbr.2018.10.040

Interfering with emotional processing resources upon associative threat memory reactivation does not affect memory retention

Author(s): Anastasia Chalkia, Lauranne Vanaken, Riet Fonteyne, Tom Beckers
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-40827-9

It takes two: Bilateral bed nuclei of the stria terminalis mediate the expression of contextual fear, but not of moderate cued fear

Author(s): Kelly Luyck, Lutgarde Arckens, Bart Nuttin, Laura Luyten
Published in: Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, Page(s) 109920, ISSN 0278-5846
Publisher: Elsevier BV
DOI: 10.1016/j.pnpbp.2020.109920

Acute but Not Permanent Effects of Propranolol on Fear Memory Expression in Humans

Author(s): Anastasia Chalkia, Jeroen Weermeijer, Lukas Van Oudenhove, Tom Beckers
Published in: Frontiers in Human Neuroscience, Issue 13, 2019, ISSN 1662-5161
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnhum.2019.00051

Electrolytic post-training lesions of the bed nucleus of the stria terminalis block startle potentiation in a cued fear conditioning procedure

Author(s): Kelly Luyck, Bart Nuttin, Laura Luyten
Published in: Brain Structure and Function, 2018, ISSN 1863-2653
Publisher: Springer Verlag
DOI: 10.1007/s00429-017-1591-z

Generalization and recovery of post-retrieval amnesia.

Author(s): Joaquín M. Alfei, Roque I. Ferrer Monti, Victor A. Molina, Dimitri De Bundel, Laura Luyten, Tom Beckers
Published in: Journal of Experimental Psychology: General, 2020, ISSN 0096-3445
Publisher: American Psychological Association
DOI: 10.1037/xge0000765

Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats

Author(s): Natalie Schroyens, Joaquín Matias Alfei, Anna Elisabeth Schnell, Laura Luyten, Tom Beckers
Published in: Neurobiology of Learning and Memory, Issue 166, 2019, Page(s) 107105, ISSN 1074-7427
Publisher: Academic Press
DOI: 10.1016/j.nlm.2019.107105

A Primer on Bayesian Analysis for Experimental Psychopathologists

Author(s): Angelos-Miltiadis Krypotos, Tessa Blanken, Inna Arnaudova, Dora Matzke, Tom Beckers
Published in: Journal of Experimental Psychopathology, Issue 8, 2017, Page(s) 140-157, ISSN 2043-8087
Publisher: Textrum
DOI: 10.5127/jep.057316

In Search for Boundary Conditions of Reconsolidation: A Failure of Fear Memory Interference

Author(s): Natalie Schroyens, Tom Beckers, Merel Kindt
Published in: Frontiers in Behavioral Neuroscience, Issue 11, 2017, Page(s) 65, ISSN 1662-5153
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnbeh.2017.00065

Memory Reconsolidation Interference as an Emerging Treatment for Emotional Disorders: Strengths, Limitations, Challenges, and Opportunities

Author(s): Tom Beckers, Merel Kindt
Published in: Annual Review of Clinical Psychology, Issue 13/1, 2017, Page(s) 99-121, ISSN 1548-5943
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-clinpsy-032816-045209

Low-dose systemic scopolamine disrupts context conditioning in rats

Author(s): Laura Luyten, Shauni Nuyts, Tom Beckers
Published in: Journal of Psychopharmacology, Issue 31/6, 2017, Page(s) 667-673, ISSN 0269-8811
Publisher: SAGE Publications
DOI: 10.1177/0269881117699614

Avoidance and decision making in anxiety: An introduction to the special issue

Author(s): Tom Beckers, Michelle G. Craske
Published in: Behaviour Research and Therapy, Issue 96, 2017, Page(s) 1-2, ISSN 0005-7967
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.brat.2017.05.009

Dopamine: From prediction error to psychotherapy

Author(s): Silvia Papalini, Tom Beckers, Bram Vervliet
Published in: Translational Psychiatry, 2020, ISSN 2158-3188
Publisher: Nature Publishing Group

Thesis and dissertations (3)

Mechanisms of forgetting: Boundaries and conditions for reactivation-mediated attenuation of memory expression

Author(s): Joaquín M. Alfei
Published in: 2020
Publisher: KU Leuven

Persistent remembering and directed forgetting: Appraising emotional memory attenuation techniques

Author(s): Anastasia Chalkia
Published in: 2020
Publisher: KU Leuven

Attenuating fear memory expression after retrieval: Failures to replicate, evidence for publication bias and an evaluation of reconsolidation theory

Author(s): Natalie Schroyens
Published in: 2021
Publisher: KU Leuven

Other (2)

The lack of evidence in Schiller et al. (2010) verified: Reply to Schiller, LeDoux, and Phelps (2020)

Author(s): Anastasia Chalkia, Lukas Van Oudenhove, Tom Beckers
Published in: PsyArXiv, 2021
Publisher: Society for the Improvement of Psychological Science
DOI: 10.31234/osf.io/tb72e

A critical assessment of reconsolidation interference as a tool for therapeutic forgetting

Author(s): Natalie Schroyens, Tom Beckers, Laura Luyten
Published in: OSF Preprints, 2021
Publisher: Center for Open Science
DOI: 10.31219/osf.io/4z7qx