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Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses

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Publications

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Author(s): Åsa Segerstolpe, Athanasia Palasantza, Pernilla Eliasson, Eva-Marie Andersson, Anne-Christine Andréasson, Xiaoyan Sun, Simone Picelli, Alan Sabirsh, Maryam Clausen, Magnus K. Bjursell, David M. Smith, Maria Kasper, Carina Ämmälä, Rickard Sandberg
Published in: Cell Metabolism, Issue 24/4, 2016, Page(s) 593-607, ISSN 1550-4131
DOI: 10.1016/j.cmet.2016.08.020

Single-cell sequencing of the small-RNA transcriptome

Author(s): Omid R Faridani, Ilgar Abdullayev, Michael Hagemann-Jensen, John P Schell, Fredrik Lanner, Rickard Sandberg
Published in: Nature Biotechnology, Issue 34/12, 2016, Page(s) 1264-1266, ISSN 1087-0156
DOI: 10.1038/nbt.3701

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA–seq

Author(s): Björn Reinius, Jeff E Mold, Daniel Ramsköld, Qiaolin Deng, Per Johnsson, Jakob Michaëlsson, Jonas Frisén, Rickard Sandberg
Published in: Nature Genetics, Issue 48/11, 2016, Page(s) 1430-1435, ISSN 1061-4036
DOI: 10.1038/ng.3678

Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation

Author(s): Björn Reinius, Rickard Sandberg
Published in: Nature Reviews Genetics, Issue 16/11, 2015, Page(s) 653-664, ISSN 1471-0056
DOI: 10.1038/nrg3888

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

Author(s): Sophie Petropoulos, Daniel Edsgärd, Björn Reinius, Qiaolin Deng, Sarita Pauliina Panula, Simone Codeluppi, Alvaro Plaza Reyes, Sten Linnarsson, Rickard Sandberg, Fredrik Lanner
Published in: Cell, Issue 165/4, 2016, Page(s) 1012-1026, ISSN 0092-8674
DOI: 10.1016/j.cell.2016.03.023

scphaser: haplotype inference using single-cell RNA-seq data

Author(s): Daniel Edsgärd, Björn Reinius, Rickard Sandberg
Published in: Bioinformatics, Issue 32/19, 2016, Page(s) 3038-3040, ISSN 1367-4803
DOI: 10.1093/bioinformatics/btw484