Modulation of the Ubiquitin Proteasome System During Multiple Stages of the Poxvirus Lifecycle

Project Information

UbiProPox

Grant agreement ID: 649101

DOI

10.3030/649101

Project closed

EC signature date 26 March 2015

Start date 1 September 2015

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 270 000,00

EU contribution

€ 2 270 000,00

Coordinated by

THE UNIVERSITY OF BIRMINGHAM
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

Acrylamide inhibits vaccinia virus through vimentin‐independent anti‐viral granule formation

Author(s): Jennifer J. Wood, Ian J. White, Jerzy Samolej, Jason Mercer
Published in: Cellular Microbiology, Issue 23/8, 2021, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.13334

Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress

Author(s): Moona Huttunen, Jerzy Samolej, Robert J Evans, Artur Yakimovich, Ian J White, Janos Kriston-Vizi, Juan Martin-Serrano, Wesley I Sundquist, Eva-Maria Frickel, Jason Mercer
Published in: Life Science Alliance, Issue 4/8, 2021, Page(s) e202000910, ISSN 2575-1077
Publisher: LSA
DOI: 10.26508/lsa.202000910

The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages

Author(s): Nagisa Yoshida, Marie-Charlotte Domart, Christopher J. Peddie, Artur Yakimovich, Maria J. Mazon-Moya, Thomas A. Hawkins, Lucy Collinson, Jason Mercer, Eva-Maria Frickel, Serge Mostowy
Published in: Disease Models & Mechanisms, Issue 13/7, 2020, ISSN 1754-8403
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dmm.043091

NanoJ-SQUIRREL: quantitative mapping and minimisation of super-resolution optical imaging artefacts

Author(s): Mercer, Jason; Leterrier, Christophe; Pereira, Pedro; Henriques, Ricardo; Culley, Siân; Albrecht, David; Jacobs, Caron
Published in: Nature Methods, Issue 15(4), 2018, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1101/158279

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper

Author(s): Robert D. M. Gray, Jason Mercer, Ricardo Henriques
Published in: Journal of Visualized Experiments, Issue 122, 2017, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/55471

Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives

Author(s): Yakimovich, Artur; Huttunen, Moona; Zehnder, Benno; Coulter, Lesley J.; Gould, Victoria; Schneider, Christoph; Kopf, Manfred; McInnes, Colin J.; Greber, Urs F.; Mercer, Jason
Published in: Journal of Virology, Issue 91(18), 2017, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.3929/ethz-b-000177326

Proteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence

Author(s): Karel Novy, Samuel Kilcher, Ulrich Omasits, Christopher Karl Ernst Bleck, Corina Beerli, Jakob Vowinckel, Caroline K. Martin, Mohammedyaseen Syedbasha, Alessio Maiolica, Ian White, Jason Mercer, Bernd Wollscheid
Published in: Nature Microbiology, Issue 3/5, 2018, Page(s) 588-599, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-018-0142-6

VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy

Author(s): Gray, Robert D.M.; Ricardo Henriques; Jerzy Samolej; Christopher Karl Ernst Bleck; Kathrin Maria Scherer; Pedro Matos Pereira; Corina Beerli; Jason Mercer
Published in: Scientific Reports , 6 , Article 29132. (2016), Issue 1, 2016, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep29132

Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility

Author(s): Corina Beerli, Artur Yakimovich, Samuel Kilcher, Glennys V. Reynoso, Gotthold Fläschner, Daniel J. Müller, Heather D. Hickman, Jason Mercer
Published in: Nature Microbiology, Issue 4/2, 2019, Page(s) 216-225, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-018-0288-2

Nanoscale polarization of the entry fusion complex of vaccinia virus drives efficient fusion

Author(s): Robert D. M. Gray, David Albrecht, Corina Beerli, Moona Huttunen, Gary H. Cohen, Ian J. White, Jemima J. Burden, Ricardo Henriques, Jason Mercer
Published in: Nature Microbiology, Issue 4/10, 2019, Page(s) 1636-1644, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-019-0488-4

Fix Your Membrane Receptor Imaging: Actin Cytoskeleton and CD4 Membrane Organization Disruption by Chemical Fixation

Author(s): Pedro M. Pereira, David Albrecht, Siân Culley, Caron Jacobs, Mark Marsh, Jason Mercer, Ricardo Henriques
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2019.00675

Defining host–pathogen interactions employing an artificial intelligence workflow

Author(s): Daniel Fisch, Artur Yakimovich, Barbara Clough, Joseph Wright, Monique Bunyan, Michael Howell, Jason Mercer, Eva Frickel
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.40560

Modulation of Early Host Innate Immune Response by an Avipox Vaccine Virus’ Lateral Body Protein

Author(s): Efstathios S. Giotis, Stephen M. Laidlaw, Susanna R. Bidgood, David Albrecht, Jemima J. Burden, Rebecca C. Robey, Jason Mercer, Michael A. Skinner
Published in: Biomedicines, Issue 8/12, 2020, Page(s) 634, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines8120634

Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection

Author(s): Artur Yakimovich, Moona Huttunen, Jerzy Samolej, Barbara Clough, Nagisa Yoshida, Serge Mostowy, Eva-Maria Frickel, Jason Mercer
Published in: mSphere, Issue 5/5, 2020, ISSN 2379-5042
Publisher: ASM
DOI: 10.1128/msphere.00836-20

Book chapters (1)

Image-Based Quantitation of Host Cell–Toxoplasma gondii Interplay Using HRMAn: A Host Response to Microbe Analysis Pipeline

Author(s): Daniel Fisch, Artur Yakimovich, Barbara Clough, Jason Mercer, Eva-Maria Frickel
Published in: Toxoplasma gondii - Methods and Protocols, Issue 2071, 2020, Page(s) 411-433, ISBN 978-1-4939-9856-2
Publisher: Springer US
DOI: 10.1007/978-1-4939-9857-9_21

Non-peer reviewed articles (2)

mSphere of Influence: the Rise of Artificial Intelligence in Infection Biology

Author(s): Artur Yakimovich
Published in: mSphere, Issue 4/3, 2019, ISSN 2379-5042
Publisher: ASM Journals
DOI: 10.1128/mSphere.00315-19

NanoJ: a high-performance open-source super-resolution microscopy toolbox

Author(s): Romain F Laine, Kalina L Tosheva, Nils Gustafsson, Robert D M Gray, Pedro Almada, David Albrecht, Gabriel T Risa, Fredrik Hurtig, Ann-Christin Lindås, Buzz Baum, Jason Mercer, Christophe Leterrier, Pedro M Pereira, Siân Culley, Ricardo Henriques
Published in: Journal of Physics D: Applied Physics, Issue 52/16, 2019, Page(s) 163001, ISSN 0022-3727
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6463/ab0261