Objective Multicellular organisms require an accurate coordination of multiple growth programs to develop. In plants, the lateral growth is the process by which stems and roots grow in diameter. Lateral growth is a pivotal process for plant development that (i) provides the mechanical stability that plants need to expand their growth and sustain their structures and (ii) brings about large amounts of extremely useful plant biomass, especially in the form of wood in trees. Lateral growth is mediated by a specialised group of stem cells collectively called cambium. Remarkably for such a crucial cell-type for plant development and biomass generation, very little is known about the genetic regulation of cambium. Dr. Agusti’s lab has identified new strong potential cambium regulators through a novel approach that combines natural variation and Genome-Wide Association Studies (GWAS) in the model plant Arabidopsis thaliana. Based on the sophisticated skills that I acquired in the field of tree genetics and genomics and on the large experience on genomics techniques held in the lab of Dr. Agusti, I present a project that will:1) Characterise the role of new potential cambium regulators identified in Dr. Agusti’s lab in Arabidopsis and Aspen trees, using state of the art genetic and molecular techniques.2) Discover new cambium regulators in Arabidopsis by expanding the natural variation and GWAS approach previously used in Agusti’s lab.3) Translate the results obtained through 1) and 2) into the generation of new Aspen varieties (using state of the art techniques on tree genetics and genomics that I have extensively used in the past) with the view of enhancing biomass production in Aspen in the form of wood.Results will (i) unravel new and fundamental aspects of the genetic regulation of cambium activity, illuminating our general understanding on plant development and (ii) strongly impact on Europe excellence by enhancing our capacity for plant biomass production. Fields of science natural sciencescomputer and information sciencessoftwarenatural sciencesphysical sciencesastronomyplanetary sciencesplanetsnatural sciencesbiological sciencesgeneticsgenomesagricultural sciencesagricultural biotechnologybiomassagricultural sciencesagriculture, forestry, and fisheriesforestry Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Call for proposal H2020-MSCA-IF-2014 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Net EU contribution € 195 454,80 Address Wellington square university offices OX1 2JD Oxford United Kingdom See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
