Since its begging, the REDOxHEART project has managed to recruit 140 patients through the Oxford CABG Bio-resource biobank. We have collected their right atrium appendages (RAA), which is a small part of the small chamber of the heart, and have already measured ROS production from several sources. We have also completed clinical data and several wnt ligand gene expression. We are planning to perform further studies to evaluate the association between the level of ROS production, wnt ligands and patients’ outcomes. In addition, we have used an established heart cell model in order to perform experiments that enhanced our understanding on how some substances are activated by the wnt ligands and ultimately lead to increased ROS production.