Characterization of Key Epigenetic Targets in Hepatic Fibrosis and Hepatocellular Carcinoma Development. Generation of New Antifibrotic and Antitumoral Drugs.

Project Information

TARGEPILIVER

Grant agreement ID: 657125

DOI

10.3030/657125

Project closed

EC signature date 16 March 2015

Start date 1 December 2015

End date 22 March 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 170 121,60

EU contribution

€ 170 121,60

Coordinated by

FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

Author(s): Gloria Alvarez-Sola, Iker Uriarte, M Ujue Latasa, Maite G Fernandez-Barrena, Raquel Urtasun, Maria Elizalde, Marina Barcena-Varela, Maddalen Jiménez, Haisul C Chang, Roberto Barbero, Victoria Catalán, Amaia Rodríguez, Gema Frühbeck, José M Gallego-Escuredo, Aleix Gavaldà-Navarro, Francesc Villarroya, Carlos M Rodriguez-Ortigosa, Fernando J Corrales, Jesus Prieto, Pedro Berraondo, Carmen Bera
Published in: Gut, Issue 66/10, 2017, Page(s) 1818-1828, ISSN 0017-5749
Publisher: BMJ Publishing Group
DOI: 10.1136/gutjnl-2016-312975

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications

Author(s): Gloria Alvarez-Sola, Iker Uriarte, Maria U. Latasa, Maddalen Jimenez, Marina Barcena-Varela, Eva Santamaría, Raquel Urtasun, Carlos Rodriguez-Ortigosa, Jesús Prieto, Pedro Berraondo, Maite G. Fernandez-Barrena, Carmen Berasain, Matías A. Avila
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1864/4, 2018, Page(s) 1326-1334, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2017.06.025

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

Author(s): Gloria Alvarez-Sola, Iker Uriarte, Maria U Latasa, Maddalen Jimenez, Marina Barcena-Varela, Eva Santamaría, Raquel Urtasun, Carlos Rodriguez-Ortigosa, Jesús Prieto, Fernando J Corrales, Anna Baulies, Carmen García-Ruiz, Jose C Fernandez-Checa, Pedro Berraondo, Maite G Fernandez-Barrena, Carmen Berasain, Matías A Avila
Published in: Cell Death and Disease, Issue 8/10, 2017, Page(s) e3083, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/cddis.2017.480

New evidence supporting the biliary bicarbonate umbrella theory

Author(s): M.G. Fernandez-Barrena, M. Barcena-Varela, J.M. Banales
Published in: Clinics and Research in Hepatology and Gastroenterology, Issue 41/2, 2017, Page(s) 126-128, ISSN 2210-7401
Publisher: Elsevier Masson
DOI: 10.1016/j.clinre.2016.09.004