Characterization of Key Epigenetic Targets in Hepatic Fibrosis and Hepatocellular Carcinoma Development. Generation of New Antifibrotic and Antitumoral Drugs.

Project Information

TARGEPILIVER

Grant agreement ID: 657125

DOI 10.3030/657125

Project closed

EC signature date 16 March 2015

Start date 1 December 2015

End date 22 March 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 170 121,60

EU contribution € 170 121,60

Coordinated by

FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
Spain

Publications

Peer reviewed articles (4)

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

Author(s): Gloria Alvarez-Sola, Iker Uriarte, M Ujue Latasa, Maite G Fernandez-Barrena, Raquel Urtasun, Maria Elizalde, Marina Barcena-Varela, Maddalen Jiménez, Haisul C Chang, Roberto Barbero, Victoria Catalán, Amaia Rodríguez, Gema Frühbeck, José M Gallego-Escuredo, Aleix Gavaldà-Navarro, Francesc Villarroya, Carlos M Rodriguez-Ortigosa, Fernando J Corrales, Jesus Prieto, Pedro Berraondo, Carmen Bera
Published in: Gut, Issue 66/10, 2017, Page(s) 1818-1828, ISSN 0017-5749
Publisher: BMJ Publishing Group
DOI: 10.1136/gutjnl-2016-312975

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications

Author(s): Gloria Alvarez-Sola, Iker Uriarte, Maria U. Latasa, Maddalen Jimenez, Marina Barcena-Varela, Eva Santamaría, Raquel Urtasun, Carlos Rodriguez-Ortigosa, Jesús Prieto, Pedro Berraondo, Maite G. Fernandez-Barrena, Carmen Berasain, Matías A. Avila
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Issue 1864/4, 2018, Page(s) 1326-1334, ISSN 0925-4439
Publisher: Elsevier BV
DOI: 10.1016/j.bbadis.2017.06.025

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

Author(s): Gloria Alvarez-Sola, Iker Uriarte, Maria U Latasa, Maddalen Jimenez, Marina Barcena-Varela, Eva Santamaría, Raquel Urtasun, Carlos Rodriguez-Ortigosa, Jesús Prieto, Fernando J Corrales, Anna Baulies, Carmen García-Ruiz, Jose C Fernandez-Checa, Pedro Berraondo, Maite G Fernandez-Barrena, Carmen Berasain, Matías A Avila
Published in: Cell Death and Disease, Issue 8/10, 2017, Page(s) e3083, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/cddis.2017.480

New evidence supporting the biliary bicarbonate umbrella theory

Author(s): M.G. Fernandez-Barrena, M. Barcena-Varela, J.M. Banales
Published in: Clinics and Research in Hepatology and Gastroenterology, Issue 41/2, 2017, Page(s) 126-128, ISSN 2210-7401
Publisher: Elsevier Masson
DOI: 10.1016/j.clinre.2016.09.004