High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle

Información del proyecto

HighTPSAFM

Identificador del acuerdo de subvención: 659079

DOI

10.3030/659079

Proyecto finalizado el 7 Abril 2016

Fecha de la firma de la CE 16 Junio 2015

Fecha de inicio 1 Mayo 2016

Fecha de finalización 30 Abril 2018

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 170 121,60

Aportación de la UE

€ 170 121,60

Coordinado por

UNIVERSIDAD DE MURCIA
Spain

Objetivo

The project HighTPSAFM (High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle) intends to develop and implement high throughput and high resolution modes of atomic force microscopy (AFM) with spectroscopy-like capabilities and enhanced sensitivity to detect and identify heterogeneous compositional contrast. The aim is to develop the instrumentation in order to answer and elucidate mechanisms of timely questions in molecular and cell biology, i.e. related to the Histone Code Hypothesis and bacterial resistance. Unresolved requirements involve simultaneously be minimally invasive while providing high throughput, high resolution and spectroscopic capabilities, such as chemical identification, or footprinting in the case of bacteria, cells and other biological systems, with high sensitivity. The applicant has already gained international recognition for his achievements in the field and become an emerging scientist of note. The project further represents a significant advance in the applicants’ career by expanding it towards applications in the fields of biotechnology and complementary optical techniques. The project will establish the candidate, and collaborators, in the field by building a European interdisciplinary and international team of growing stature and recognition. The project includes the building of a competitive network of collaborators in Europe with partners that will jointly serve to support and systematically fulfil the objectives. The two year project will further provide sufficient experience to the candidate as an independent researcher while being supported by an international referent in nanotechnology with state of the art infrastructure and facilities at of the Universidad de Murcia UM (CIOyN, Spain) and at Linz (JKU, Austria) as secondment. These have proven experience in the development and translation of microscopy instrumentation and new acquisition and data processing techniques.

Ámbito científico (EuroSciVoc)

• ciencias naturales › ciencias biológicas › microbiología › bacteriología
• ciencias naturales › ciencias biológicas › biología celular
• ciencias naturales › ciencias físicas › óptica › microscopía
• ciencias naturales › informática y ciencias de la información › ciencia de datos › tratamiento de datos
• ciencias naturales › ciencias físicas › óptica › espectroscopia

Palabras clave

• multifrequency dynamic atomic force microscopy
• force spectroscopy
• epigenetics
• chromatin structure
• histone modifications
• bacterial resistance

Programa(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions PROGRAMA PRINCIPAL
  
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
  

Tema(s)

• MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF)
  

Régimen de financiación

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Convocatoria de propuestas

H2020-MSCA-IF-2014

Coordinador

UNIVERSIDAD DE MURCIA

• Aportación neta de la UEn: € 170 121,60
• Dirección: AVENIDA TENIENTE FLOMESTA S/N - EDIFICIO CONVALECENCIA ; 30003 Murcia ; España
• Región: Sur › Región de Murcia › Murcia
• Tipo de actividad: Higher or Secondary Education Establishments
• Coste total: € 170 121,60