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Bioinformatic approaches to identify and detect both disease- and drug-related genomic alterations in breast cancer patients

Publications

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Author(s): Alejandra Bruna, Oscar M. Rueda, Wendy Greenwood, Ankita Sati Batra, Maurizio Callari, Rajbir Nath Batra, Katherine Pogrebniak, Jose Sandoval, John W. Cassidy, Ana Tufegdzic-Vidakovic, Stephen-John Sammut, Linda Jones, Elena Provenzano, Richard Baird, Peter Eirew, James Hadfield, Matthew Eldridge, Anne McLaren-Douglas, Andrew Barthorpe, Howard Lightfoot, Mark J. O’Connor, Joe Gray, Javier C
Published in: Cell, Issue 167/1, 2016, Page(s) 260-274.e22, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2016.08.041

Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers

Author(s): Maurizio Callari, Stephen-John Sammut, Leticia De Mattos-Arruda, Alejandra Bruna, Oscar M. Rueda, Suet-Feung Chin, Carlos Caldas
Published in: Genome Medicine, Issue 9/1, 2017, ISSN 1756-994X
Publisher: BioMed Central
DOI: 10.1186/s13073-017-0425-1

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