Linking the intrinsic protein dynamics to function in glutamate transporters

Project Information

MEMDYN

Grant agreement ID: 660083

DOI

10.3030/660083

Project terminated on 26 June 2019

EC signature date 26 June 2015

Start date 1 April 2016

End date 31 March 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 246 668,40

EU contribution

€ 246 668,40

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder

Author(s): Didar Ciftci, Gerard H. M. Huysmans, Xiaoyu Wang, Changhao He, Daniel Terry, Zhou Zhou, Gabriel Fitzgerald, Scott C. Blanchard, Olga Boudker
Published in: Science Advances, Issue 6/22, 2020, Page(s) eaaz1949, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.aaz1949

Molecular basis for the folding of β-helical autotransporter passenger domains

Author(s): Xiaojun Yuan, Matthew D. Johnson, Jing Zhang, Alvin W. Lo, Mark A. Schembri, Lakshmi C. Wijeyewickrema, Robert N. Pike, Gerard H. M. Huysmans, Ian R. Henderson, Denisse L. Leyton
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-03593-2

Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog

Author(s): Yun Huang, Xiaoyu Wang, Guohua Lv, Asghar M. Razavi, Gerard H. M. Huysmans, Harel Weinstein, Clay Bracken, David Eliezer, Olga Boudker
Published in: Nature Chemical Biology, Issue 16/9, 2020, Page(s) 1006-1012, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/s41589-020-0561-6

The high‐energy transition state of the glutamate transporter homologue GltPh

Author(s): Gerard H M Huysmans, Didar Ciftci, Xiaoyu Wang, Scott C Blanchard, Olga Boudker
Published in: The EMBO Journal, Issue 40/1, 2021, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020105415

Millisecond dynamics of an unlabeled amino acid transporter

Author(s): Tina R. Matin, George R. Heath, Gerard H. M. Huysmans, Olga Boudker, Simon Scheuring
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-18811-z