Skip to main content

Moving from genome wide association to elucidating causal mechanisms of electrocardiographic traits

Publications

Relationship of Arterial Stiffness Index and Pulse Pressure With Cardiovascular Disease and Mortality

Author(s): M. Abdullah Said, Ruben N. Eppinga, Erik Lipsic, Niek Verweij, Pim van der Harst
Published in: Journal of the American Heart Association, 7/2, 2018, Page(s) e007621, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/JAHA.117.007621

Identification of 15 novel risk loci for coronary artery disease and genetic risk of recurrent events, atrial fibrillation and heart failure

Author(s): Niek Verweij, Ruben N. Eppinga, Yanick Hagemeijer, Pim van der Harst
Published in: Scientific Reports, 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-03062-8

Telomere Length and Risk of Cardiovascular Disease and Cancer

Author(s): M. Abdullah Said, Ruben N. Eppinga, Yanick Hagemeijer, Niek Verweij, Pim van der Harst
Published in: Journal of the American College of Cardiology, 70/4, 2017, Page(s) 506-507, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2017.05.044

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery DiseaseNovelty and Significance

Author(s): Pim van der Harst, Niek Verweij
Published in: Circulation Research, 122/3, 2018, Page(s) 433-443, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.312086

Refining Thromboembolic Risk in the General Population

Author(s): Ruben N. Eppinga, Minke H.T. Hartman, Niek Verweij, J. Joep van der Harst, Michiel Rienstra, Pim van der Harst
Published in: Journal of the American College of Cardiology, 70/3, 2017, Page(s) 403-404, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2017.05.022

Discovery of novel heart rate-associated loci using the Exome Chip

Author(s): Marten E. van den Berg, Helen R. Warren, Claudia P. Cabrera, Niek Verweij, Borbala Mifsud, Jeffrey Haessler, Nathan A. Bihlmeyer, Yi-Ping Fu, Stefan Weiss, Henry J. Lin, Niels Grarup, Ruifang Li-Gao, Giorgio Pistis, Nabi Shah, Jennifer A. Brody, Martina Müller-Nurasyid, Honghuang Lin, Hao Mei, Albert V. Smith, Leo-Pekka Lyytikäinen, Leanne M. Hall, Jessica van Setten, Stella Trompet, Bram P. Pri
Published in: Human Molecular Genetics, 26/12, 2017, Page(s) 2346-2363, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx113

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Author(s): Helen R Warren, Evangelos Evangelou, Claudia P Cabrera, He Gao, Meixia Ren, Borbala Mifsud, Ioanna Ntalla, Praveen Surendran, Chunyu Liu, James P Cook, Aldi T Kraja, Fotios Drenos, Marie Loh, Niek Verweij, Jonathan Marten, Ibrahim Karaman, Marcelo P Segura Lepe, Paul F O'Reilly, Joanne Knight, Harold Snieder, Norihiro Kato, Jiang He, E Shyong Tai, M Abdullah Said, David Porteous, Maris Alver, Neil
Published in: Nature Genetics, 49/3, 2017, Page(s) 403-415, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/ng.3768

Heart Rate Recovery 10 Seconds After Cessation of Exercise Predicts Death

Author(s): Yordi J. van de Vegte, Pim van der Harst, Niek Verweij
Published in: Journal of the American Heart Association, 7/8, 2018, Page(s) e008341, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/JAHA.117.008341

Genetic study links components of the autonomous nervous system to heart-rate profile during exercise

Author(s): Niek Verweij, Yordi J. van de Vegte, Pim van der Harst
Published in: Nature Communications, 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-03395-6

Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality

Author(s): Ruben N Eppinga, Yanick Hagemeijer, Stephen Burgess, David A Hinds, Kari Stefansson, Daniel F Gudbjartsson, Dirk J van Veldhuisen, Patricia B Munroe, Niek Verweij, Pim van der Harst
Published in: Nature Genetics, 48/12, 2016, Page(s) 1557-1563, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/ng.3708

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

Author(s): Niek Verweij, Irene Mateo Leach, Aaron Isaacs, Dan E. Arking, Joshua C. Bis, Tune H. Pers, Marten E. Van Den Berg, Leo-Pekka Lyytikäinen, Phil Barnett, Xinchen Wang, Elsayed Z. Soliman, Cornelia M. Van Duijn, Mika Kähönen, Dirk J. Van Veldhuisen, Jan A. Kors, Olli T. Raitakari, Claudia T. Silva, Terho Lehtimäki, Hans L. Hillege, Joel N. Hirschhorn, Laurie A. Boyer, Wiek H. Van Gilst, Alvaro Al
Published in: Human Molecular Genetics, 25/10, 2016, Page(s) 2093-2103, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddw058

Meta-analysis of exome chip variants identifies rare and common variants associated with electrocardiographic left ventricular mass

Author(s): G. Kosova, N. Verweij, P. van der Harst, C. Newton-Cheh, on behalf of the CHARGE Consortium EX-EKG working group.
Published in: ASHG congress 2015 Baltimore, MD, 2015
Publisher: ASHG congress 2015 Baltimore, MD

Datasets

Heart rate profile during exercise summary statistics

Author(s): Verweij, Niek
Published in: Mendeley

Additional file 1: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Author(s): Prins, Bram; Mead, Timothy; Brody, Jennifer; Gardar Sveinbjornsson; Ntalla, Ioanna; Bihlmeyer, Nathan; Berg, Marten Van Den; Bork-Jensen, Jette; Cappellani, Stefania; Duijvenboden, Stefan Van; Klena, Nikolai; Gabriel, George; Xiaoqin Liu; Cagri Gulec; Grarup, Niels; Haessler, Jeffrey; Hall, Leanne; Iorio, Annamaria; Isaacs, Aaron; Ruifang Li-Gao; Honghuang Lin; Ching-Ti Liu; Leo-Pekka LyytikäInen; Marten, Jonathan; Mei, Hao; Mßller-Nurasyid, Martina; Orini, Michele; Sandosh Padmanabhan; Radmanesh, Farid; Ramirez, Julia; Robino, Antonietta; Schwartz, Molly; Setten, Jessica Van; Smith, Albert; Verweij, Niek; Warren, Helen; Weiss, Stefan; Alonso, Alvaro; Arnar, David; Bots, Michiel; Boer, Rudolf De; Dominiczak, Anna; Eijgelsheim, Mark; Ellinor, Patrick; Xiuqing Guo; Felix, Stephan; Harris, Tamara; Hayward, Caroline; Heckbert, Susan; Huang, Paul; J. Jukema; KäHÜnen, Mika; Kors, Jan; Lambiase, Pier; Launer, Lenore; Li, Man; Linneberg, Allan; Nelson, Christopher; Pedersen, Oluf; Perez, Marco; Peters, Annette; Polasek, Ozren; Psaty, Bruce; Raitakari, Olli; Rice, Kenneth; Rotter, Jerome; Sinner, Moritz; Elsayed Soliman; Spector, Tim; Strauch, Konstantin; Thorsteinsdottir, Unnur; Tinker, Andrew; Trompet, Stella; AndrÊ Uitterlinden; Vaartjes, Ilonca; Meer, Peter Van Der; VÜlker, Uwe; VÜlzke, Henry; Waldenberger, Melanie; Wilson, James; Zhijun Xie; Asselbergs, Folkert; DÜrr, Marcus; Duijn, Cornelia Van; Gasparini, Paolo; Gudbjartsson, Daniel; Gudnason, Vilmundur; Hansen, Torben; KääB, Stefan; JøRgen Kanters; Kooperberg, Charles; LehtimäKi, Terho; Lin, Henry; Lubitz, Steven; Mook-Kanamori, Dennis; Conti, Francesco; Newton-Cheh, Christopher; Rosand, Jonathan; Rudan, Igor; Nilesh Samani; Sinagra, Gianfranco; Smith, Blair; Holm, Hilma; Stricker, Bruno; Ulivi, Sheila; Sotoodehnia, Nona; Suneel Apte; Harst, Pim Van Der; Stefansson, Kari; Munroe, Patricia; Arking, Dan; Lo, Cecilia; Yalda Jamshidi
Published in: figshare

Additional file 3: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Author(s): Prins, Bram; Mead, Timothy; Brody, Jennifer; Gardar Sveinbjornsson; Ntalla, Ioanna; Bihlmeyer, Nathan; Berg, Marten Van Den; Bork-Jensen, Jette; Cappellani, Stefania; Duijvenboden, Stefan Van; Klena, Nikolai; Gabriel, George; Xiaoqin Liu; Cagri Gulec; Grarup, Niels; Haessler, Jeffrey; Hall, Leanne; Iorio, Annamaria; Isaacs, Aaron; Ruifang Li-Gao; Honghuang Lin; Ching-Ti Liu; Leo-Pekka LyytikäInen; Marten, Jonathan; Mei, Hao; Mßller-Nurasyid, Martina; Orini, Michele; Sandosh Padmanabhan; Radmanesh, Farid; Ramirez, Julia; Robino, Antonietta; Schwartz, Molly; Setten, Jessica Van; Smith, Albert; Verweij, Niek; Warren, Helen; Weiss, Stefan; Alonso, Alvaro; Arnar, David; Bots, Michiel; Boer, Rudolf De; Dominiczak, Anna; Eijgelsheim, Mark; Ellinor, Patrick; Xiuqing Guo; Felix, Stephan; Harris, Tamara; Hayward, Caroline; Heckbert, Susan; Huang, Paul; J. Jukema; KäHÜnen, Mika; Kors, Jan; Lambiase, Pier; Launer, Lenore; Li, Man; Linneberg, Allan; Nelson, Christopher; Pedersen, Oluf; Perez, Marco; Peters, Annette; Polasek, Ozren; Psaty, Bruce; Raitakari, Olli; Rice, Kenneth; Rotter, Jerome; Sinner, Moritz; Elsayed Soliman; Spector, Tim; Strauch, Konstantin; Thorsteinsdottir, Unnur; Tinker, Andrew; Trompet, Stella; AndrÊ Uitterlinden; Vaartjes, Ilonca; Meer, Peter Van Der; VÜlker, Uwe; VÜlzke, Henry; Waldenberger, Melanie; Wilson, James; Zhijun Xie; Asselbergs, Folkert; DÜrr, Marcus; Duijn, Cornelia Van; Gasparini, Paolo; Gudbjartsson, Daniel; Gudnason, Vilmundur; Hansen, Torben; KääB, Stefan; JøRgen Kanters; Kooperberg, Charles; LehtimäKi, Terho; Lin, Henry; Lubitz, Steven; Mook-Kanamori, Dennis; Conti, Francesco; Newton-Cheh, Christopher; Rosand, Jonathan; Rudan, Igor; Nilesh Samani; Sinagra, Gianfranco; Smith, Blair; Holm, Hilma; Stricker, Bruno; Ulivi, Sheila; Sotoodehnia, Nona; Suneel Apte; Harst, Pim Van Der; Stefansson, Kari; Munroe, Patricia; Arking, Dan; Lo, Cecilia; Yalda Jamshidi
Published in: figshare