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NanoSmells: Artificial remote-controlled odorants

Deliverables

Group meetings

Group Meetings at Months 1, 24, and 48.: Meetings of all group members for: Project initiation at Month 1, Progress meeting at Month 24, Project closure at Month 48.

Project website

Project website at Month 2. Here we will generate a website for project reports, updates, and dissemination.

Rodent bulb maps

Rodent bulb maps at Month 47. This deliverable is the responsibility of UNIVERSITE DE GENEVE. Here they will generate bulb activation maps following activation of a single receptor. This should provide important insight on the coding rules of olfaction.

Data management plan (interim)

Data management plan at Month 6. Here we will submit a management plan.

Final Fly response

Final fly response at Month 24. This deliverable is the responsibility of MPG. We expect a final manuscript co-authored by MPG and BIU describing the neural response of the fly to artificial odorants.

Final Human response

Final human response at Month 24. This deliverable is the responsibility of WEIZMANN. We expect a final manuscript co-authored by WEIZMANN and BIU describing the perceptual and neural response of humans to artificial odorants.

Final Rodent response
Final Skin response

Final skin response at Month 24. This deliverable is the responsibility of UC3M. We expect a final manuscript co-authored by UC3M and AN describing the response of skin wounds to the artificial odorant.

4 submitted manuscripts describing 2.1-2.4

Submitted manuscripts at Month 24. This deliverable is the responsibility of all groups. We expect all the above manuscripts to be submitted.

Insect trap test

1. Insect trap test at Month 47. This deliverable is the responsibility of MPG. Here they will test an insect trap that is remotely activated.

Switchable wound treatment

Switchable wound treatment at Month 47. This deliverable is the responsibility of UC3M. Here we will test the response of wounds to remote activation in vivo. If this works, one can imagine a product worn by people at high risk of injury, e.g., fire fighters, and if they get injured, then the treatment can be remotely activated.

Human rapidly switching odors (SmelloVision)

Human rapidly switchable odors at Month 47. This deliverable is the responsibility of WEIZMANN. Here we will remotely activate an odor at percise timing with media, such as at an appropriate time in a film.

Publications

A measure of smell enables the creation of olfactory metamers

Author(s): Ravia, Aharon, Kobi Snitz, Danielle Honigstein, Maya Finkel, Rotem Zirler, Ofer Perl, Lavi Secundo, Christophe Laudamiel, David Harel, and Noam Sobel.
Published in: Nature, Issue 588, no. 7836 (2020), 2020, Page(s) 118-123, ISSN 1476-4687
Publisher: Nature
DOI: 10.1038/s41586-020-2891-7

From Nose to Brain: Un-Sensed Electrical Currents Applied in the Nose Alter Activity in Deep Brain Structures

Author(s): Tali Weiss, Sagit Shushan, Aharon Ravia, Avital Hahamy, Lavi Secundo, Aharon Weissbrod, Aya Ben-Yakov, Yael Holtzman, Smadar Cohen-Atsmoni, Yehudah Roth, Noam Sobel
Published in: Cerebral Cortex, 2016, ISSN 1047-3211
Publisher: Oxford University Press
DOI: 10.1093/cercor/bhw222

Dense encoding of natural odorants by ensembles of sparsely activated neurons in the olfactory bulb

Author(s): Gschwend O, Beroud J, Vincis R, Rodriguez I, Carleton A.
Published in: Scientific Reports, 2016, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep36514

Similarity and Strength of Glomerular Odor Representations Define a Neural Metric of Sniff-Invariant Discrimination Time

Author(s): Anindya S. Bhattacharjee, Sasank Konakamchi, Dmitrij Turaev, Roberto Vincis, Daniel Nunes, Atharva A. Dingankar, Hartwig Spors, Alan Carleton, Thomas Kuner, Nixon M. Abraham
Published in: Cell Reports, Issue 28/11, 2019, Page(s) 2966-2978.e5, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.08.015

Intellectual Property Rights

METHODS AND COMPOSITIONS FOR SELECTION OF FUNCTIONAL OLIGONUCLEOTIDES

Application/Publication number: 18 726527
Date: 2018-03-30
Applicant(s): AUGMANITY NANO LTD

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