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The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome

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Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends

Published in: ISSN 1545-9993
DOI: 10.1038/nsmb.3420

Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

Author(s): Simone Cavadini, Eric S. Fischer, Richard D. Bunker, Alessandro Potenza, Gondichatnahalli M. Lingaraju, Kenneth N. Goldie, Weaam I. Mohamed, Mahamadou Faty, Georg Petzold, Rohan E. J. Beckwith, Ritesh B. Tichkule, Ulrich Hassiepen, Wassim Abdulrahman, Radosav S. Pantelic, Syota Matsumoto, Kaoru Sugasawa, Henning Stahlberg, Nicolas H. Thomä
Published in: Nature, Issue 531/7596, 2016, Page(s) 598-603, ISSN 0028-0836
DOI: 10.1038/nature17416

Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase

Author(s): Georg Petzold, Eric S. Fischer, Nicolas H. Thomä
Published in: Nature, Issue 532/7597, 2016, Page(s) 127-130, ISSN 0028-0836
DOI: 10.1038/nature16979

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

Author(s): Quinlan L. Sievers, Georg Petzold, Richard D. Bunker, Aline Renneville, Mikołaj Słabicki, Brian J. Liddicoat, Wassim Abdulrahman, Tarjei Mikkelsen, Benjamin L. Ebert, Nicolas H. Thomä
Published in: Science, Issue 362/6414, 2018, Page(s) eaat0572, ISSN 0036-8075
DOI: 10.1126/science.aat0572