Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities

Thyroid hormone regulation of adult neural stem cell fate: A comparative analysis between rodents and primates

Author(s): Lucile Butruille, Pieter Vancamp, Barbara A. Demeneix, Sylvie Remaud
Published in: Hormones and Stem Cells, Issue 116, 2021, Page(s) 133-192, ISBN 9780323855501
Publisher: Elsevier
DOI: 10.1016/bs.vh.2021.02.009

Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

Author(s): Ana Zutinic, Gerard J Blauw, Hanno Pijl, Bart E Ballieux, Rudi G J Westendorp, Ferdinand Roelfsema, Diana van Heemst
Published in: Journal of the Endocrine Society, Issue 4/10, 2020, ISSN 2472-1972
Publisher: Journal of Endocrine Society
DOI: 10.1210/jendso/bvaa117

A molecular quantitative trait locus map for osteoarthritis

Author(s): Julia Steinberg, Lorraine Southam, Theodoros I. Roumeliotis, Matthew J. Clark, Raveen L. Jayasuriya, Diane Swift, Karan M. Shah, Natalie C. Butterfield, Roger A. Brooks, Andrew W. McCaskie, J. H. Duncan Bassett, Graham R. Williams, Jyoti S. Choudhary, J. Mark Wilkinson, Eleftheria Zeggini
Published in: Nature Communications, Issue 12/1, 2021, Page(s) 1309, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21593-7

Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications

Author(s): Evie van der Spoel, Ferdinand Roelfsema, Diana van Heemst
Published in: Frontiers in Endocrinology, Issue 12, 2021, ISSN 1664-2392
Publisher: Frontiers in Endocrinology
DOI: 10.3389/fendo.2021.619568

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Author(s): Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Me
Published in: Nature Communications, Issue 12/1, 2021, Page(s) 2444, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22517-1

Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

Author(s): Evie van der Spoel, Ferdinand Roelfsema, Abimbola A Akintola, Steffy W Jansen, P Eline Slagboom, Rudi G J Westendorp, Gerard J Blauw, Hanno Pijl, Diana van Heemst
Published in: The Journal of Clinical Endocrinology & Metabolism, Issue 105/4, 2020, Page(s) e1201-e1214, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgz253

Distribution and ultrastructural localization of the glucagon-like peptide-1 receptor (GLP-1R) in the rat brain

Author(s): Erzsébet Farkas, Anett Szilvásy-Szabó, Yvette Ruska, Richárd Sinkó, Morten Grønbech Rasch, Thomas Egebjerg, Charles Pyke, Balázs Gereben, Lotte Bjerre Knudsen, Csaba Fekete
Published in: Brain Structure and Function, Issue 226/1, 2021, Page(s) 225-245, ISSN 1863-2653
Publisher: Springer Verlag
DOI: 10.1007/s00429-020-02189-1

Thyroid Hormone and Neural Stem Cells: Repair Potential Following Brain and Spinal Cord Injury

Author(s): Pieter Vancamp, Lucile Butruille, Barbara A. Demeneix, Sylvie Remaud
Published in: Frontiers in Neuroscience, Issue 14, 2020, ISSN 1662-453X
Publisher: Frontiers in Neuroscience
DOI: 10.3389/fnins.2020.00875

Accelerating functional gene discovery in osteoarthritis

Author(s): Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J. Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Ant
Published in: Nature Communications, Issue 12/1, 2021, Page(s) 467, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20761-5

Deiodinases and Cancer

Author(s): Annarita Nappi, Maria Angela De Stefano, Monica Dentice, Domenico Salvatore
Published in: Endocrinology, Issue 162/4, 2021, ISSN 0013-7227
Publisher: The Endocrine Society
DOI: 10.1210/endocr/bqab016

Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

Author(s): Nicolien A van Vliet, Raymond Noordam, Jan B van Klinken, Rudi GJ Westendorp, JH Duncan Bassett, Graham R Williams, Diana van Heemst
Published in: Journal of Bone and Mineral Research, Issue 33/7, 2018, Page(s) 1318-1325, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3426

Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

Author(s): J.D. Gothié, A. Sébillot, C. Luongo, M. Legendre, C. Nguyen Van, K. Le Blay, M. Perret-Jeanneret, S. Remaud, B.A. Demeneix
Published in: Molecular Metabolism, Issue 6/11, 2017, Page(s) 1551-1561, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2017.08.003

The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data

Author(s): Daisy M Wopereis, Robert S Du Puy, Diana van Heemst, John P Walsh, Alexandra Bremner, Stephan J L Bakker, Douglas C Bauer, Anne R Cappola, Graziano Ceresini, Jean Degryse, Robin P F Dullaart, Martin Feller, Luigi Ferrucci, Carmen Floriani, Oscar H Franco, Massimo Iacoviello, Georgio Iervasi, Misa Imaizumi, J Wouter Jukema, Kay-Tee Khaw, Robert N Luben, Sabrina Molinaro, Matthias Nauck, Kushang V P
Published in: The Journal of Clinical Endocrinology & Metabolism, Issue 103/10, 2018, Page(s) 3658-3667, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/jc.2018-00481

Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

Author(s): Remaud , Sylvie; Ortiz , Fernando ,; Perret-Jeanneret , Marine; Aigrot , Marie-Stéphane; Gothié , Jean-David; Fekete , Csaba; Kvárta-Papp , Zsuzsanna; Gereben , Balázs; Langui , Dominique; Lubetzki , Catherine; Angulo , Maria ,; Zalc , Bernard; Demeneix , Barbara
Published in: "eLife, eLife Sciences Publication, 2017, 6, pp.e29996. 〈10.7554/eLife.29996.001〉", Issue 1, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.29996.001

Thyroid status and mortality in nonagenarians from long-lived families and the general population

Author(s): Nicolien A. van Vliet, Evie van der Spoel, Marian Beekman, P. Eline Slagboom, Gerard Jan Blauw, Jacobijn Gussekloo, Rudi G.J. Westendorp, Diana van Heemst
Published in: Aging, Issue 9/10, 2017, Page(s) 2223-2234, ISSN 1945-4589
Publisher: Aging
DOI: 10.18632/aging.101310

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

Author(s): Sungro Jo, Tatiana L. Fonseca, Barbara M. L. C. Bocco, Gustavo W. Fernandes, Elizabeth A. McAninch, Anaysa P. Bolin, Rodrigo R. Da Conceição, Joao Pedro Werneck-de-Castro, Daniele L. Ignacio, Péter Egri, Dorottya Németh, Csaba Fekete, Maria Martha Bernardi, Victoria D. Leitch, Naila S. Mannan, Katharine F. Curry, Natalie C. Butterfield, J.H. Duncan Bassett, Graham R. Williams, Balázs Gereben,
Published in: Journal of Clinical Investigation, Issue 129/1, 2019, Page(s) 230-245, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci123176

The 24-hour serum profiles of bone markers in healthy older men and women

Author(s): Evie van der Spoel, Nicole Oei, Ricardo Cachucho, Ferdinand Roelfsema, Jimmy F.P. Berbée, Gerard J. Blauw, Hanno Pijl, Natasha M. Appelman-Dijkstra, Diana van Heemst
Published in: Bone, Issue 120, 2019, Page(s) 61-69, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2018.10.002

Thyroid diseases and bone health

Author(s): G. R. Williams, J. H. D. Bassett
Published in: Journal of Endocrinological Investigation, Issue 41/1, 2018, Page(s) 99-109, ISSN 1720-8386
Publisher: Springer
DOI: 10.1007/s40618-017-0753-4

Gender-specific effects of transthyretin on neural stem cell fate in the subventricular zone of the adult mouse

Author(s): Pieter Vancamp, Jean-David Gothié, Cristina Luongo, Anthony Sébillot, Karine Le Blay, Lucile Butruille, Maurice Pagnin, Samantha J. Richardson, Barbara A. Demeneix, Sylvie Remaud
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-56156-w

Thyroid hormone regulation of neural stem cell fate: From development to ageing

Author(s): Jean‐David Gothié, Pieter Vancamp, Barbara Demeneix, Sylvie Remaud
Published in: Acta Physiologica, Issue 228/1, 2019, ISSN 1748-1708
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/apha.13316

Comparing Methods for Measurement Error Detection in Serial 24-h Hormonal Data

Author(s): Evie van der Spoel, Jungyeon Choi, Ferdinand Roelfsema, Saskia le Cessie, Diana van Heemst, Olaf M. Dekkers
Published in: Journal of Biological Rhythms, Issue 34/4, 2019, Page(s) 347-363, ISSN 0748-7304
Publisher: Sage Science Press
DOI: 10.1177/0748730419850917

Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance

Author(s): Evie van der Spoel, Nicolien A. van Vliet, Diana van Heemst
Published in: Ageing Research Reviews, Issue 56, 2019, Page(s) 100964, ISSN 1568-1637
Publisher: Elsevier BV
DOI: 10.1016/j.arr.2019.100964

The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress

Author(s): Serena Sagliocchi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Raffaele Ambrosio, Caterina Miro, Daniela Di Girolamo, Annarita Nappi, Giuseppina Mancino, Maria Angela De Stefano, Cristina Luongo, Maddalena Raia, Ashley N. Ogawa-Wong, Ann Marie Zavacki, Simona Paladino, Domenico Salvatore, Monica Dentice
Published in: Redox Biology, Issue 24, 2019, Page(s) 101228, ISSN 2213-2317
Publisher: Elsevier BV
DOI: 10.1016/j.redox.2019.101228

PYY is a negative regulator of bone mass and strength

Author(s): Victoria D. Leitch, Mary Jane Brassill, Sofia Rahman, Natalie C. Butterfield, Pattara Ma, John G. Logan, Alan Boyde, Holly Evans, Peter I. Croucher, Rachel L. Batterham, Graham R. Williams, J.H. Duncan Bassett
Published in: Bone, Issue 127, 2019, Page(s) 427-435, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2019.07.011

Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch

Author(s): Caterina Miro, Emery Di Cicco, Raffaele Ambrosio, Giuseppina Mancino, Daniela Di Girolamo, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Annarita Nappi, Maria Angela De Stefano, Cristina Luongo, Dario Antonini, Feliciano Visconte, Silvia Varricchio, Gennaro Ilardi, Luigi Del Vecchio, Stefania Staibano, Anita Boelen, Cedric Blanpain, Caterina Missero, Domenico Salvatore, Monica Dentice
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13140-2

Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone

Author(s): Ana Zutinic, Hanno Pijl, Bart E Ballieux, Ferdinand Roelfsema, Rudi G J Westendorp, Gerard J Blauw, Diana van Heemst
Published in: The Journal of Clinical Endocrinology & Metabolism, 2020, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgaa195

An essential physiological role for MCT8 in bone in male mice

Author(s): Victoria D. Leitch, Caterina Di Cosmo, Xiao-Hui Liao, Sam O'Boy, Thomas M. Galliford, Holly Evans, Peter I. Croucher, Alan Boyde, Alexandra Dumitrescu, Roy E. Weiss, Samuel Refetoff, Graham R. Williams, J.H. Duncan Bassett
Published in: Endocrinology, Issue en.2017-00399, 2017, Page(s) In Press, ISSN 0013-7227
Publisher: The Endocrine Society
DOI: 10.1210/en.2017-00399

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Author(s): Jean-David Gothié, Barbara Demeneix, Sylvie Remaud
Published in: Molecular and Cellular Endocrinology, 2017, Page(s) S0303-7207(17)30289-7, ISSN 0303-7207
Publisher: Elsevier BV
DOI: 10.1016/j.mce.2017.05.020

Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study

Author(s): Maxime M. Bos, Roelof A. J. Smit, Stella Trompet, Diana van Heemst, Raymond Noordam
Published in: The Journal of Clinical Endocrinology & Metabolism, Issue 102/6, 2017, Page(s) 1960-1970, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/jc.2016-2816

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

Author(s): Saira Hameed, Michael Patterson, Waljit S. Dhillo, Sofia A. Rahman, Yue Ma, Christopher Holton, Apostolos Gogakos, Giles S.H. Yeo, Brian Y.H. Lam, Joseph Polex-Wolf, Wiebke Fenske, Jimmy Bell, Jelena Anastasovska, Jacques Samarut, Stephen R. Bloom, J.H. Duncan Bassett, Graham R. Williams, James V. Gardiner
Published in: Cell Reports, Issue 19/11, 2017, Page(s) 2202-2209, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.05.066

The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas

Author(s): Annarita Nappi, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Giuseppina Mancino, Raffaele Ambrosio, Cristina Luongo, Daniela Di Girolamo, Maria Angela De Stefano, Tommaso Porcelli, Mariano Stornaiuolo, Monica Dentice
Published in: Cancers, Issue 12/3, 2020, Page(s) 715, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12030715

The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation

Author(s): Giuseppina Mancino, Annarita Sibilio, Cristina Luongo, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Annarita Nappi, Serena Sagliocchi, Raffaele Ambrosio, Maria Angela De Stefano, Daniela Di Girolamo, Tommaso Porcelli, Melania Murolo, Federica Saracino, Giuseppe Perruolo, Pietro Formisano, Mariano Stornaiuolo, Monica Dentice
Published in: Thyroid, Issue 30/7, 2020, Page(s) 1066-1078, ISSN 1050-7256
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2019.0557

A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System

Author(s): Erzsébet Farkas, Edina Varga, Balázs Kovács, Anett Szilvásy-Szabó, Antonieta Cote-Vélez, Zoltán Péterfi, Magdalini Matziari, Mónika Tóth, Dóra Zelena, Zsolt Mezriczky, Andrea Kádár, Dóra Kővári, Masahiko Watanabe, Masanobu Kano, Ken Mackie, Balázs Rózsa, Yvette Ruska, Blanka Tóth, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Balázs Gereben, Ronald M. Lechan, Jean-Louis Charl
Published in: iScience, Issue 23/3, 2020, Page(s) 100921, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2020.100921

Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs

Author(s): Edina Varga, Erzsébet Farkas, Györgyi Zséli, Andrea Kádár, Alexandra Venczel, Dóra Kővári, Dorottya Németh, Zoltán Máté, Ferenc Erdélyi, András Horváth, Ottó Szenci, Masahiko Watanabe, Ronald M. Lechan, Balázs Gereben, Csaba Fekete
Published in: Thyroid, Issue 29/12, 2019, Page(s) 1858-1868, ISSN 1050-7256
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2019.0357

Deiodinases and their intricate role in thyroid hormone homeostasis

Author(s): Cristina Luongo, Monica Dentice, Domenico Salvatore
Published in: Nature Reviews Endocrinology, Issue 15/8, 2019, Page(s) 479-488, ISSN 1759-5029
Publisher: Nature Publishing Group
DOI: 10.1038/s41574-019-0218-2

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

Author(s): Tatiana L. Fonseca, Gustavo W. Fernandes, Barbara M. L. C. Bocco, Ali Keshavarzian, Shriram Jakate, Terrence M. Donohue, Balázs Gereben, Antonio C. Bianco
Published in: Alcoholism: Clinical and Experimental Research, Issue 43/7, 2019, Page(s) 1376-1383, ISSN 0145-6008
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1111/acer.14027

Paradigms of Dynamic Control of Thyroid Hormone Signaling

Author(s): Antonio C Bianco, Alexandra Dumitrescu, Balázs Gereben, Miriam O Ribeiro, Tatiana L Fonseca, Gustavo W Fernandes, Barbara M L C Bocco
Published in: Endocrine Reviews, Issue 40/4, 2019, Page(s) 1000-1047, ISSN 0163-769X
Publisher: The Endocrine Society
DOI: 10.1210/er.2018-00275

Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone

Author(s): Cristina Luongo, Lucile Butruille, Anthony Sébillot, Karine Le Blay, Markus Schwaninger, Heike Heuer, Barbara A. Demeneix, Sylvie Remaud
Published in: Stem Cell Reports, Issue 16/2, 2021, Page(s) 337-353, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.12.009

Relationships Between 24-h LH and Testosterone Concentrations and With Other Pituitary Hormones in Healthy Older Men

Author(s): Evie van der Spoel, Ferdinand Roelfsema, Diana van Heemst
Published in: Journal of the Endocrine Society, 2021, ISSN 2472-1972
Publisher: Oxford University Press
DOI: 10.1210/jendso/bvab075

Deiodinases and stem cells: an intimate relationship

Author(s): D. Salvatore
Published in: Journal of Endocrinological Investigation, Issue 41/1, 2018, Page(s) 59-66, ISSN 1720-8386
Publisher: Springer Nature
DOI: 10.1007/s40618-017-0737-4

The importance of the RET gene in thyroid cancer and therapeutic implications

Author(s): Domenico Salvatore, Massimo Santoro, Martin Schlumberger
Published in: Nature Reviews Endocrinology, Issue 17/5, 2021, Page(s) 296-306, ISSN 1759-5029
Publisher: Nature Publishing Group
DOI: 10.1038/s41574-021-00470-9

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

Author(s): Emery Di Cicco, Carla Moran, W. Edward Visser, Annarita Nappi, Erik Schoenmakers, Pamela Todd, Greta Lyons, Mehul Dattani, Raffaele Ambrosio, Silvia Parisi, Domenico Salvatore, Krishna Chatterjee, Monica Dentice
Published in: Thyroid, 2021, ISSN 1050-7256
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2020.0391

Genetically Determined Higher TSH Is Associated With a Lower Risk of Diabetes Mellitus in Individuals With Low BMI

Author(s): Maxime M Bos, Nicolien A van Vliet, Simon P Mooijaart, Raymond Noordam, Diana van Heemst
Published in: The Journal of Clinical Endocrinology & Metabolism, Issue 106/7, 2021, Page(s) e2502-e2511, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgab277

Thyroid hormone signaling and deiodinase actions in muscle stem/progenitor cells

Author(s): Raffaele Ambrosio, Maria Angela De Stefano, Daniela Di Girolamo, Domenico Salvatore
Published in: Molecular and Cellular Endocrinology, Issue 459, 2017, Page(s) 79-83, ISSN 0303-7207
Publisher: Elsevier BV
DOI: 10.1016/j.mce.2017.06.014

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

Author(s): Anna L. Swan, Christine Schütt, Jan Rozman, Maria del Mar Muñiz Moreno, Stefan Brandmaier, Michelle Simon, Stefanie Leuchtenberger, Mark Griffiths, Robert Brommage, Piia Keskivali-Bond, Harald Grallert, Thomas Werner, Raffaele Teperino, Lore Becker, Gregor Miller, Ala Moshiri, John R. Seavitt, Derek D. Cissell, Terrence F. Meehan, Elif F. Acar, Christopher J. Lelliott, Ann M. Flenniken, Marie-Fr
Published in: PLOS Genetics, Issue 16/12, 2020, Page(s) e1009190, ISSN 1553-7404
Publisher: PLOS Genetics
DOI: 10.1371/journal.pgen.1009190

Thyroid function and risk of anemia: a multivariable-adjusted and Mendelian Randomization analysis in the UK Biobank

Author(s): Nicolien A. van Vliet, Annelies E.P. Kamphuis, Wendy P.J. den Elzen, Gerard J. Blauw, Jacobijn Gussekloo, Raymond Noordam, Diana van Heemst
Published in: 2021
Publisher: MedRxiv
DOI: 10.1101/2021.06.24.21259436

Accelerating functional gene discovery in osteoarthritis

Author(s): Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Anto
Published in: BioRxiv, Issue Posted November 10, 2019., 2019
Publisher: BioRxiv
DOI: 10.1101/836221

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease

Author(s): Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana
Published in: BioRxiv, Issue Posted April 22, 2020., 2020
Publisher: BioRxiv
DOI: 10.1101/2020.04.20.051409

Decoding the genomic basis of osteoarthritis

Author(s): Julia Steinberg, Lorraine Southam, Natalie C Butterfield, Theodoros I Roumeliotis, Andreas Fontalis, Matthew J Clark, Raveen L Jayasuriya, Diane Swift, Karan M Shah, Katherine F Curry, Roger A Brooks, Andrew W McCaskie, Christopher J. Lelliott, Jyoti S Choudhary, JH Duncan Bassett, Graham R Williams, J Mark Wilkinson, Eleftheria Zeggini
Published in: BioRxiv, Issue Posted January 31, 2020, 2020
Publisher: BioRxiv
DOI: 10.1101/835850

Genetic and environmental determinants of cardiometabolic health

Author(s): M.M. Bos
Published in: 2020, Page(s) all
Publisher: .

The endocrinology of familial longevity : time series analyses of different hormonal axes and their interrelationships

Author(s): Evie van der Spoel
Published in: 2019, Page(s) all
Publisher: .

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