Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Establishment of external THYRAGE web site
Establishment of the THYRAGE consortium website
Production of a booklet to disseminate THYRAGE results to the lay public

Final plan for dissemination and exploitation of the project’s results

Publicaciones

Thyroid hormone regulation of adult neural stem cell fate: A comparative analysis between rodents and primates

Autores: Lucile Butruille, Pieter Vancamp, Barbara A. Demeneix, Sylvie Remaud
Publicado en: Hormones and Stem Cells, Edición 116, 2021, Página(s) 133-192, ISBN 9780323855501
Editor: Elsevier
DOI: 10.1016/bs.vh.2021.02.009

Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

Autores: Ana Zutinic, Gerard J Blauw, Hanno Pijl, Bart E Ballieux, Rudi G J Westendorp, Ferdinand Roelfsema, Diana van Heemst
Publicado en: Journal of the Endocrine Society, Edición 4/10, 2020, ISSN 2472-1972
Editor: Journal of Endocrine Society
DOI: 10.1210/jendso/bvaa117

A molecular quantitative trait locus map for osteoarthritis

Autores: Julia Steinberg, Lorraine Southam, Theodoros I. Roumeliotis, Matthew J. Clark, Raveen L. Jayasuriya, Diane Swift, Karan M. Shah, Natalie C. Butterfield, Roger A. Brooks, Andrew W. McCaskie, J. H. Duncan Bassett, Graham R. Williams, Jyoti S. Choudhary, J. Mark Wilkinson, Eleftheria Zeggini
Publicado en: Nature Communications, Edición 12/1, 2021, Página(s) 1309, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-21593-7

Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications

Autores: Evie van der Spoel, Ferdinand Roelfsema, Diana van Heemst
Publicado en: Frontiers in Endocrinology, Edición 12, 2021, ISSN 1664-2392
Editor: Frontiers in Endocrinology
DOI: 10.3389/fendo.2021.619568

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Autores: Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Me
Publicado en: Nature Communications, Edición 12/1, 2021, Página(s) 2444, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-22517-1

Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

Autores: Evie van der Spoel, Ferdinand Roelfsema, Abimbola A Akintola, Steffy W Jansen, P Eline Slagboom, Rudi G J Westendorp, Gerard J Blauw, Hanno Pijl, Diana van Heemst
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 105/4, 2020, Página(s) e1201-e1214, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgz253

Distribution and ultrastructural localization of the glucagon-like peptide-1 receptor (GLP-1R) in the rat brain

Autores: Erzsébet Farkas, Anett Szilvásy-Szabó, Yvette Ruska, Richárd Sinkó, Morten Grønbech Rasch, Thomas Egebjerg, Charles Pyke, Balázs Gereben, Lotte Bjerre Knudsen, Csaba Fekete
Publicado en: Brain Structure and Function, Edición 226/1, 2021, Página(s) 225-245, ISSN 1863-2653
Editor: Springer Verlag
DOI: 10.1007/s00429-020-02189-1

Thyroid Hormone and Neural Stem Cells: Repair Potential Following Brain and Spinal Cord Injury

Autores: Pieter Vancamp, Lucile Butruille, Barbara A. Demeneix, Sylvie Remaud
Publicado en: Frontiers in Neuroscience, Edición 14, 2020, ISSN 1662-453X
Editor: Frontiers in Neuroscience
DOI: 10.3389/fnins.2020.00875

Accelerating functional gene discovery in osteoarthritis

Autores: Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J. Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Ant
Publicado en: Nature Communications, Edición 12/1, 2021, Página(s) 467, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-20761-5

Deiodinases and Cancer

Autores: Annarita Nappi, Maria Angela De Stefano, Monica Dentice, Domenico Salvatore
Publicado en: Endocrinology, Edición 162/4, 2021, ISSN 0013-7227
Editor: The Endocrine Society
DOI: 10.1210/endocr/bqab016

Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

Autores: Nicolien A van Vliet, Raymond Noordam, Jan B van Klinken, Rudi GJ Westendorp, JH Duncan Bassett, Graham R Williams, Diana van Heemst
Publicado en: Journal of Bone and Mineral Research, Edición 33/7, 2018, Página(s) 1318-1325, ISSN 0884-0431
Editor: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3426

Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

Autores: J.D. Gothié, A. Sébillot, C. Luongo, M. Legendre, C. Nguyen Van, K. Le Blay, M. Perret-Jeanneret, S. Remaud, B.A. Demeneix
Publicado en: Molecular Metabolism, Edición 6/11, 2017, Página(s) 1551-1561, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2017.08.003

The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data

Autores: Daisy M Wopereis, Robert S Du Puy, Diana van Heemst, John P Walsh, Alexandra Bremner, Stephan J L Bakker, Douglas C Bauer, Anne R Cappola, Graziano Ceresini, Jean Degryse, Robin P F Dullaart, Martin Feller, Luigi Ferrucci, Carmen Floriani, Oscar H Franco, Massimo Iacoviello, Georgio Iervasi, Misa Imaizumi, J Wouter Jukema, Kay-Tee Khaw, Robert N Luben, Sabrina Molinaro, Matthias Nauck, Kushang V P
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 103/10, 2018, Página(s) 3658-3667, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/jc.2018-00481

Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain

Autores: Remaud , Sylvie; Ortiz , Fernando ,; Perret-Jeanneret , Marine; Aigrot , Marie-Stéphane; Gothié , Jean-David; Fekete , Csaba; Kvárta-Papp , Zsuzsanna; Gereben , Balázs; Langui , Dominique; Lubetzki , Catherine; Angulo , Maria ,; Zalc , Bernard; Demeneix , Barbara
Publicado en: "eLife, eLife Sciences Publication, 2017, 6, pp.e29996. 〈10.7554/eLife.29996.001〉", Edición 1, 2017, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/eLife.29996.001

Thyroid status and mortality in nonagenarians from long-lived families and the general population

Autores: Nicolien A. van Vliet, Evie van der Spoel, Marian Beekman, P. Eline Slagboom, Gerard Jan Blauw, Jacobijn Gussekloo, Rudi G.J. Westendorp, Diana van Heemst
Publicado en: Aging, Edición 9/10, 2017, Página(s) 2223-2234, ISSN 1945-4589
Editor: Aging
DOI: 10.18632/aging.101310

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

Autores: Sungro Jo, Tatiana L. Fonseca, Barbara M. L. C. Bocco, Gustavo W. Fernandes, Elizabeth A. McAninch, Anaysa P. Bolin, Rodrigo R. Da Conceição, Joao Pedro Werneck-de-Castro, Daniele L. Ignacio, Péter Egri, Dorottya Németh, Csaba Fekete, Maria Martha Bernardi, Victoria D. Leitch, Naila S. Mannan, Katharine F. Curry, Natalie C. Butterfield, J.H. Duncan Bassett, Graham R. Williams, Balázs Gereben,
Publicado en: Journal of Clinical Investigation, Edición 129/1, 2019, Página(s) 230-245, ISSN 0021-9738
Editor: American Society for Clinical Investigation
DOI: 10.1172/jci123176

The 24-hour serum profiles of bone markers in healthy older men and women

Autores: Evie van der Spoel, Nicole Oei, Ricardo Cachucho, Ferdinand Roelfsema, Jimmy F.P. Berbée, Gerard J. Blauw, Hanno Pijl, Natasha M. Appelman-Dijkstra, Diana van Heemst
Publicado en: Bone, Edición 120, 2019, Página(s) 61-69, ISSN 8756-3282
Editor: Elsevier BV
DOI: 10.1016/j.bone.2018.10.002

Thyroid diseases and bone health

Autores: G. R. Williams, J. H. D. Bassett
Publicado en: Journal of Endocrinological Investigation, Edición 41/1, 2018, Página(s) 99-109, ISSN 1720-8386
Editor: Springer
DOI: 10.1007/s40618-017-0753-4

Gender-specific effects of transthyretin on neural stem cell fate in the subventricular zone of the adult mouse

Autores: Pieter Vancamp, Jean-David Gothié, Cristina Luongo, Anthony Sébillot, Karine Le Blay, Lucile Butruille, Maurice Pagnin, Samantha J. Richardson, Barbara A. Demeneix, Sylvie Remaud
Publicado en: Scientific Reports, Edición 9/1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-56156-w

Thyroid hormone regulation of neural stem cell fate: From development to ageing

Autores: Jean‐David Gothié, Pieter Vancamp, Barbara Demeneix, Sylvie Remaud
Publicado en: Acta Physiologica, Edición 228/1, 2019, ISSN 1748-1708
Editor: Blackwell Publishing Inc.
DOI: 10.1111/apha.13316

Comparing Methods for Measurement Error Detection in Serial 24-h Hormonal Data

Autores: Evie van der Spoel, Jungyeon Choi, Ferdinand Roelfsema, Saskia le Cessie, Diana van Heemst, Olaf M. Dekkers
Publicado en: Journal of Biological Rhythms, Edición 34/4, 2019, Página(s) 347-363, ISSN 0748-7304
Editor: Sage Science Press
DOI: 10.1177/0748730419850917

Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance

Autores: Evie van der Spoel, Nicolien A. van Vliet, Diana van Heemst
Publicado en: Ageing Research Reviews, Edición 56, 2019, Página(s) 100964, ISSN 1568-1637
Editor: Elsevier BV
DOI: 10.1016/j.arr.2019.100964

The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress

Autores: Serena Sagliocchi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Raffaele Ambrosio, Caterina Miro, Daniela Di Girolamo, Annarita Nappi, Giuseppina Mancino, Maria Angela De Stefano, Cristina Luongo, Maddalena Raia, Ashley N. Ogawa-Wong, Ann Marie Zavacki, Simona Paladino, Domenico Salvatore, Monica Dentice
Publicado en: Redox Biology, Edición 24, 2019, Página(s) 101228, ISSN 2213-2317
Editor: Elsevier BV
DOI: 10.1016/j.redox.2019.101228

PYY is a negative regulator of bone mass and strength

Autores: Victoria D. Leitch, Mary Jane Brassill, Sofia Rahman, Natalie C. Butterfield, Pattara Ma, John G. Logan, Alan Boyde, Holly Evans, Peter I. Croucher, Rachel L. Batterham, Graham R. Williams, J.H. Duncan Bassett
Publicado en: Bone, Edición 127, 2019, Página(s) 427-435, ISSN 8756-3282
Editor: Elsevier BV
DOI: 10.1016/j.bone.2019.07.011

Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch

Autores: Caterina Miro, Emery Di Cicco, Raffaele Ambrosio, Giuseppina Mancino, Daniela Di Girolamo, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Annarita Nappi, Maria Angela De Stefano, Cristina Luongo, Dario Antonini, Feliciano Visconte, Silvia Varricchio, Gennaro Ilardi, Luigi Del Vecchio, Stefania Staibano, Anita Boelen, Cedric Blanpain, Caterina Missero, Domenico Salvatore, Monica Dentice
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-13140-2

Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone

Autores: Ana Zutinic, Hanno Pijl, Bart E Ballieux, Ferdinand Roelfsema, Rudi G J Westendorp, Gerard J Blauw, Diana van Heemst
Publicado en: The Journal of Clinical Endocrinology & Metabolism, 2020, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgaa195

An essential physiological role for MCT8 in bone in male mice

Autores: Victoria D. Leitch, Caterina Di Cosmo, Xiao-Hui Liao, Sam O'Boy, Thomas M. Galliford, Holly Evans, Peter I. Croucher, Alan Boyde, Alexandra Dumitrescu, Roy E. Weiss, Samuel Refetoff, Graham R. Williams, J.H. Duncan Bassett
Publicado en: Endocrinology, Edición en.2017-00399, 2017, Página(s) In Press, ISSN 0013-7227
Editor: The Endocrine Society
DOI: 10.1210/en.2017-00399

Comparative approaches to understanding thyroid hormone regulation of neurogenesis

Autores: Jean-David Gothié, Barbara Demeneix, Sylvie Remaud
Publicado en: Molecular and Cellular Endocrinology, 2017, Página(s) S0303-7207(17)30289-7, ISSN 0303-7207
Editor: Elsevier BV
DOI: 10.1016/j.mce.2017.05.020

Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study

Autores: Maxime M. Bos, Roelof A. J. Smit, Stella Trompet, Diana van Heemst, Raymond Noordam
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 102/6, 2017, Página(s) 1960-1970, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/jc.2016-2816

Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight

Autores: Saira Hameed, Michael Patterson, Waljit S. Dhillo, Sofia A. Rahman, Yue Ma, Christopher Holton, Apostolos Gogakos, Giles S.H. Yeo, Brian Y.H. Lam, Joseph Polex-Wolf, Wiebke Fenske, Jimmy Bell, Jelena Anastasovska, Jacques Samarut, Stephen R. Bloom, J.H. Duncan Bassett, Graham R. Williams, James V. Gardiner
Publicado en: Cell Reports, Edición 19/11, 2017, Página(s) 2202-2209, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2017.05.066

The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas

Autores: Annarita Nappi, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Giuseppina Mancino, Raffaele Ambrosio, Cristina Luongo, Daniela Di Girolamo, Maria Angela De Stefano, Tommaso Porcelli, Mariano Stornaiuolo, Monica Dentice
Publicado en: Cancers, Edición 12/3, 2020, Página(s) 715, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12030715

The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation

Autores: Giuseppina Mancino, Annarita Sibilio, Cristina Luongo, Emery Di Cicco, Caterina Miro, Annunziata Gaetana Cicatiello, Annarita Nappi, Serena Sagliocchi, Raffaele Ambrosio, Maria Angela De Stefano, Daniela Di Girolamo, Tommaso Porcelli, Melania Murolo, Federica Saracino, Giuseppe Perruolo, Pietro Formisano, Mariano Stornaiuolo, Monica Dentice
Publicado en: Thyroid, Edición 30/7, 2020, Página(s) 1066-1078, ISSN 1050-7256
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2019.0557

A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System

Autores: Erzsébet Farkas, Edina Varga, Balázs Kovács, Anett Szilvásy-Szabó, Antonieta Cote-Vélez, Zoltán Péterfi, Magdalini Matziari, Mónika Tóth, Dóra Zelena, Zsolt Mezriczky, Andrea Kádár, Dóra Kővári, Masahiko Watanabe, Masanobu Kano, Ken Mackie, Balázs Rózsa, Yvette Ruska, Blanka Tóth, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Balázs Gereben, Ronald M. Lechan, Jean-Louis Charl
Publicado en: iScience, Edición 23/3, 2020, Página(s) 100921, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2020.100921

Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs

Autores: Edina Varga, Erzsébet Farkas, Györgyi Zséli, Andrea Kádár, Alexandra Venczel, Dóra Kővári, Dorottya Németh, Zoltán Máté, Ferenc Erdélyi, András Horváth, Ottó Szenci, Masahiko Watanabe, Ronald M. Lechan, Balázs Gereben, Csaba Fekete
Publicado en: Thyroid, Edición 29/12, 2019, Página(s) 1858-1868, ISSN 1050-7256
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2019.0357

Deiodinases and their intricate role in thyroid hormone homeostasis

Autores: Cristina Luongo, Monica Dentice, Domenico Salvatore
Publicado en: Nature Reviews Endocrinology, Edición 15/8, 2019, Página(s) 479-488, ISSN 1759-5029
Editor: Nature Publishing Group
DOI: 10.1038/s41574-019-0218-2

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

Autores: Tatiana L. Fonseca, Gustavo W. Fernandes, Barbara M. L. C. Bocco, Ali Keshavarzian, Shriram Jakate, Terrence M. Donohue, Balázs Gereben, Antonio C. Bianco
Publicado en: Alcoholism: Clinical and Experimental Research, Edición 43/7, 2019, Página(s) 1376-1383, ISSN 0145-6008
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1111/acer.14027

Paradigms of Dynamic Control of Thyroid Hormone Signaling

Autores: Antonio C Bianco, Alexandra Dumitrescu, Balázs Gereben, Miriam O Ribeiro, Tatiana L Fonseca, Gustavo W Fernandes, Barbara M L C Bocco
Publicado en: Endocrine Reviews, Edición 40/4, 2019, Página(s) 1000-1047, ISSN 0163-769X
Editor: The Endocrine Society
DOI: 10.1210/er.2018-00275

Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone

Autores: Cristina Luongo, Lucile Butruille, Anthony Sébillot, Karine Le Blay, Markus Schwaninger, Heike Heuer, Barbara A. Demeneix, Sylvie Remaud
Publicado en: Stem Cell Reports, Edición 16/2, 2021, Página(s) 337-353, ISSN 2213-6711
Editor: Cell Press
DOI: 10.1016/j.stemcr.2020.12.009

Relationships Between 24-h LH and Testosterone Concentrations and With Other Pituitary Hormones in Healthy Older Men

Autores: Evie van der Spoel, Ferdinand Roelfsema, Diana van Heemst
Publicado en: Journal of the Endocrine Society, 2021, ISSN 2472-1972
Editor: Oxford University Press
DOI: 10.1210/jendso/bvab075

Deiodinases and stem cells: an intimate relationship

Autores: D. Salvatore
Publicado en: Journal of Endocrinological Investigation, Edición 41/1, 2018, Página(s) 59-66, ISSN 1720-8386
Editor: Springer Nature
DOI: 10.1007/s40618-017-0737-4

The importance of the RET gene in thyroid cancer and therapeutic implications

Autores: Domenico Salvatore, Massimo Santoro, Martin Schlumberger
Publicado en: Nature Reviews Endocrinology, Edición 17/5, 2021, Página(s) 296-306, ISSN 1759-5029
Editor: Nature Publishing Group
DOI: 10.1038/s41574-021-00470-9

Germ Line Mutations in the Thyroid Hormone Receptor Alpha Gene Predispose to Cutaneous Tags and Melanocytic Nevi

Autores: Emery Di Cicco, Carla Moran, W. Edward Visser, Annarita Nappi, Erik Schoenmakers, Pamela Todd, Greta Lyons, Mehul Dattani, Raffaele Ambrosio, Silvia Parisi, Domenico Salvatore, Krishna Chatterjee, Monica Dentice
Publicado en: Thyroid, 2021, ISSN 1050-7256
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/thy.2020.0391

Genetically Determined Higher TSH Is Associated With a Lower Risk of Diabetes Mellitus in Individuals With Low BMI

Autores: Maxime M Bos, Nicolien A van Vliet, Simon P Mooijaart, Raymond Noordam, Diana van Heemst
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 106/7, 2021, Página(s) e2502-e2511, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgab277

Thyroid hormone signaling and deiodinase actions in muscle stem/progenitor cells

Autores: Raffaele Ambrosio, Maria Angela De Stefano, Daniela Di Girolamo, Domenico Salvatore
Publicado en: Molecular and Cellular Endocrinology, Edición 459, 2017, Página(s) 79-83, ISSN 0303-7207
Editor: Elsevier BV
DOI: 10.1016/j.mce.2017.06.014

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

Autores: Anna L. Swan, Christine Schütt, Jan Rozman, Maria del Mar Muñiz Moreno, Stefan Brandmaier, Michelle Simon, Stefanie Leuchtenberger, Mark Griffiths, Robert Brommage, Piia Keskivali-Bond, Harald Grallert, Thomas Werner, Raffaele Teperino, Lore Becker, Gregor Miller, Ala Moshiri, John R. Seavitt, Derek D. Cissell, Terrence F. Meehan, Elif F. Acar, Christopher J. Lelliott, Ann M. Flenniken, Marie-Fr
Publicado en: PLOS Genetics, Edición 16/12, 2020, Página(s) e1009190, ISSN 1553-7404
Editor: PLOS Genetics
DOI: 10.1371/journal.pgen.1009190

Thyroid function and risk of anemia: a multivariable-adjusted and Mendelian Randomization analysis in the UK Biobank

Autores: Nicolien A. van Vliet, Annelies E.P. Kamphuis, Wendy P.J. den Elzen, Gerard J. Blauw, Jacobijn Gussekloo, Raymond Noordam, Diana van Heemst
Publicado en: 2021
Editor: MedRxiv
DOI: 10.1101/2021.06.24.21259436

Accelerating functional gene discovery in osteoarthritis

Autores: Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Anto
Publicado en: BioRxiv, Edición Posted November 10, 2019., 2019
Editor: BioRxiv
DOI: 10.1101/836221

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease

Autores: Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana
Publicado en: BioRxiv, Edición Posted April 22, 2020., 2020
Editor: BioRxiv
DOI: 10.1101/2020.04.20.051409

Decoding the genomic basis of osteoarthritis

Autores: Julia Steinberg, Lorraine Southam, Natalie C Butterfield, Theodoros I Roumeliotis, Andreas Fontalis, Matthew J Clark, Raveen L Jayasuriya, Diane Swift, Karan M Shah, Katherine F Curry, Roger A Brooks, Andrew W McCaskie, Christopher J. Lelliott, Jyoti S Choudhary, JH Duncan Bassett, Graham R Williams, J Mark Wilkinson, Eleftheria Zeggini
Publicado en: BioRxiv, Edición Posted January 31, 2020, 2020
Editor: BioRxiv
DOI: 10.1101/835850

Genetic and environmental determinants of cardiometabolic health

Autores: M.M. Bos
Publicado en: 2020, Página(s) all
Editor: .

The endocrinology of familial longevity : time series analyses of different hormonal axes and their interrelationships

Autores: Evie van der Spoel
Publicado en: 2019, Página(s) all
Editor: .

Derechos de propiedad intelectual

TRANSGENIC MOUSE FOR THE ASSESSMENT OF THYROID HORMONE (TH) ACTION

Número de solicitud/publicación: 15 828366
Fecha: 2015-11-30
Solicitante(s): HUN REN KISERLETI ORVOSTUDOMANYI KUTATOINTEZET

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