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Continuous Regional Analysis Device for neonate Lung

Objective

Each year 15 million babies are born prematurely and many suffer from respiratory failure due to immaturity of the lung and lack of control of breathing. Although respiratory support, especially mechanical ventilation, can improve their survival, it also causes severe injury to the vulnerable lung resulting in severe and chronic pulmonary morbidity lasting in to adulthood. Heterogeneity of lung aeration, resulting in areas of lung over inflation and lung collapse, plays a crucial part in the risk of mortality and morbidity due to respiratory failure. This distribution of lung aeration cannot be detected by currently available bedside monitoring tools and imaging methods. Thus, an imaging technique for continuous non-invasive bedside monitoring of infants lung function is urgently needed. In order to address this, CRADL will use EIT technology to establish a monitoring tool for interventions in the paediatric population.
Electrical impedance tomography (EIT) is a non-radiative, inexpensive technique that can facilitate real time dynamic monitoring of lung aeration, and recent studies have shown that it is effective in monitoring aeration in preterm babies. CRADL will show how EIT can provide new cost effective, easy to use, respiratory management tools and clinical protocols that can be universally adopted to reduce deaths and disability in preterm babies by delivering a tool that provides continuous, non-invasive, radiation free, bedside information on regional lung aeration and ventilation during daily clinical care of (preterm) infants and children with respiratory failure. CRADL will also assess the effectiveness, efficacy and safety of such a system in guiding respiratory management and supportive care of the most common causes of paediatric respiratory failure (respiratory distress syndrome, bronchiolitis and acute respiratory distress syndrome), with the final goal of reducing short and long term adverse effects of disease and its treatment in this populat

Call for proposal

H2020-PHC-2014-2015

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Sub call

H2020-PHC-2015-two-stage

Coordinator

MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION
Net EU contribution
€ 997 500,00
Address
The Burroughs, Hendon .
NW4 4BT London
United Kingdom

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Region
London Outer London — West and North West Barnet
Activity type
Higher or Secondary Education Establishments
Other funding
€ 997 500,00

Participants (10)

UNIVERSITY COLLEGE LONDON
United Kingdom
Net EU contribution
€ 1 067 302,50
Address
Gower Street
WC1E 6BT London

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 067 302,50
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Germany
Net EU contribution
€ 514 690,00
Address
Olshausenstrasse 40
24118 Kiel

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Region
Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 514 690,00
Ministry of Health of the Republic of Cyprus
Cyprus
Net EU contribution
€ 137 500,00
Address
1 Prodromou Street & 17 Chilonos Street 1 & 17
1448 Nicosia

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Region
Κύπρος Κύπρος Κύπρος
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 137 500,00
FILANTHROPIKO IDRYMA VIOIATRIKON EREVNON
Cyprus
Net EU contribution
€ 162 500,00
Address
Po Box 24039
1700 Lefkosia

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Region
Κύπρος Κύπρος Κύπρος
Activity type
Other
Other funding
€ 162 500,00
UNIVERSITE DE GENEVE
Switzerland
Net EU contribution
€ 0,00
Address
Rue Du General Dufour 24
1211 Geneve

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Region
Schweiz/Suisse/Svizzera Région lémanique Genève
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
LINNEUNIVERSITETET
Sweden
Net EU contribution
€ 355 025,00
Address
Linnaeus University
35195 Vaxjo

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Region
Södra Sverige Småland med öarna Kronobergs län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 355 025,00
SENTEC AG
Switzerland
Net EU contribution
€ 0,00
Address
Ringstrasse 39
4106 Therwil

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Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Net EU contribution
€ 323 750,00
Address
Meibergdreef 15
1105AZ Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Other funding
€ 323 750,00
STUDIO FIFIELD SRL
Italy
Net EU contribution
€ 584 062,50
Address
Via Pietro Colletta 69
20137 Milano

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 584 062,50
PANAXEA BV
Netherlands
Net EU contribution
€ 92 000,00
Address
Science Park 400 Matrix Ii Unit 3.1
1098 XH Amsterdam

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 92 000,00