Deliverables
A SyBil-AA website that will include a professional video presentation of SyBil-AA´s scientific goals and activities and many other features will be posted once the project starts and will be used as an important communication platform for all external recipients.
Regression and explorative methods as well as expert analysis will be used to extract relevant features that mediate graph properties and network model performance. Inter-species comparison for relevant overlaps of this information, e.g. differences in functional connectivity between patients and controls during task performance or induced by interventions may be used as “seed” regions for the analysis of connectivity in the animal models and vice versa. Overlapping brain regions responsive to treatment will be identified and compared with available information on brain site-specific intervention for functional validation. In this way high priority brain regions will be identified for testing the effects of novel drugs on functional and anatomical connectivity as potential markers for medication development.
Recommendations for new network based clinical trials in systems medicine of alcoholismBased on this integrative analysis of the complete data sets from all WPs and the existing literature we will formulate translational recommendations for new therapeutic strategies and targets for proposing new clinical trials and developing respective protocols.
Kick-off Meeting reportIn WP1 we will organize a kick-off meeting at the start of the funding period (month 2-3) to define the objectives of each WP in detail, define the contribution of everyone to the overall goals, agree upon milestones and deliverables, and to talk about the next steps.
Targeted Publication in Addiction-related journalsFor a wide distribution of information about our Sybil-AA project we decided to prepare a targeted publication with Science Impact Ltd, a leading science communication company that successfully targets wide array of stakeholders ranging from academic institutions, industry, politics, governments and other interest groups. The publication will appear in the September issue of Impact – Healthcare, an issue that specifically focusses on Addiction.
Publications
Author(s):
Vicente Pallarés , Mateusz Dudek, Andrea Moreno, Úrsula Pérez-Ramírez, David Moratal, Mia Haaranen, Roberto Ciccocioppo, Wolfgang H Sommer, Santiago Canals, Petri Hyytiä
Published in:
Behavioral Pharmacology, 2020, ISSN 0955-8810
Publisher:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1097/fbp.0000000000000582
Author(s):
Simone Pfarr, Laura Schaaf, Janine K. Reinert, Elisabeth Paul, Frank Herrmannsdörfer, Martin Roßmanith, Thomas Kuner, Anita C. Hansson, Rainer Spanagel, Christoph Körber, Wolfgang H. Sommer
Published in:
The Journal of Neuroscience, Issue 38/14, 2018, Page(s) 3507-3519, ISSN 0270-6474
Publisher:
Society for Neuroscience
DOI:
10.1523/jneurosci.0026-18.2018
Author(s):
Martin Fungisai Gerchen, Martina Kirsch, Nathalie Bahs, Patrick Halli, Sarah Gerhardt, Axel Schäfer, Wolfgang H. Sommer, Falk Kiefer, Peter Kirsch
Published in:
BMC Psychiatry, Issue 18/1, 2018, ISSN 1471-244X
Publisher:
BioMed Central
DOI:
10.1186/s12888-018-1604-3
Author(s):
Cécile Bordier, Carlo Nicolini, Giulia Forcellini, Angelo Bifone
Published in:
NeuroImage: Clinical, 2018, ISSN 2213-1582
Publisher:
Elsevier BV
DOI:
10.1016/j.nicl.2018.02.035
Author(s):
Gino Del Ferraro, Andrea Moreno, Byungjoon Min, Flaviano Morone, Úrsula Pérez-Ramírez, Laura Pérez-Cervera, Lucas C. Parra, Andrei Holodny, Santiago Canals, Hernán A. Makse
Published in:
Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-018-04718-3
Author(s):
Natalie Hirth, Marcus W. Meinhardt, Hamid R. Noori, Humberto Salgado, Oswaldo Torres-Ramirez, Stefanie Uhrig, Laura Broccoli, Valentina Vengeliene, Martin Roßmanith, Stéphanie Perreau-Lenz, Georg Köhr, Wolfgang H. Sommer, Rainer Spanagel, Anita C. Hansson
Published in:
Proceedings of the National Academy of Sciences, Issue 113/11, 2016, Page(s) 3024-3029, ISSN 0027-8424
Publisher:
National Academy of Sciences
DOI:
10.1073/pnas.1506012113
Author(s):
Alejandro Cosa, Andrea Moreno, Jesús Pacheco-Torres, Roberto Ciccocioppo, Petri Hyytiä, Wolfgang H. Sommer, David Moratal, Santiago Canals
Published in:
Addiction Biology, 2016, ISSN 1355-6215
Publisher:
Taylor & Francis
DOI:
10.1111/adb.12418
Author(s):
Hamid R. Noori, Alejandro Cosa Linan, Rainer Spanagel
Published in:
European Neuropsychopharmacology, Issue 26/9, 2016, Page(s) 1419-1430, ISSN 0924-977X
Publisher:
Elsevier BV
DOI:
10.1016/j.euroneuro.2016.06.013
Author(s):
Szabolcs Horvát, Răzvan Gămănuț, Mária Ercsey-Ravasz, Loïc Magrou, Bianca Gămănuț, David C. Van Essen, Andreas Burkhalter, Kenneth Knoblauch, Zoltán Toroczkai, Henry Kennedy
Published in:
PLOS Biology, Issue 14/7, 2016, Page(s) e1002512, ISSN 1545-7885
Publisher:
Public Library of Science
DOI:
10.1371/journal.pbio.1002512
Author(s):
Anita C. Hansson, Gerhard Gründer, Natalie Hirth, Hamid R. Noori, Rainer Spanagel, Wolfgang H. Sommer
Published in:
Neuroscience & Biobehavioral Reviews, 2018, ISSN 0149-7634
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.neubiorev.2018.09.010
Author(s):
Annegret Habich, Santiago Canals, Stefan Klöppel
Published in:
Current Opinion in Neurology, Issue 29/4, 2016, Page(s) 453-458, ISSN 1350-7540
Publisher:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1097/WCO.0000000000000353
Author(s):
Zsolt I. Lázár, István Papp, Levente Varga, Ferenc Járai-Szabó, Dávid Deritei, Mária Ercsey-Ravasz
Published in:
Physical Review E, Issue 95/2, 2017, ISSN 2470-0045
Publisher:
Physics and Society
DOI:
10.1103/PhysRevE.95.022306
Author(s):
Cécile Bordier, Carlo Nicolini, Angelo Bifone
Published in:
Frontiers in Neuroscience, Issue 11, 2017, Page(s) 441, ISSN 1662-453X
Publisher:
Frontiers Research Foundation
DOI:
10.3389/fnins.2017.00441
Author(s):
Carlo Nicolini, Vladimir Vlasov, Angelo Bifone
Published in:
Physical Review E, Issue 98/2, 2018, ISSN 2470-0045
Publisher:
American Physical Society
DOI:
10.1103/PhysRevE.98.022322
Author(s):
Aleksandra M. Herman, Hugo D. Critchley, Theodora Duka
Published in:
European Journal of Neuroscience, 2018, ISSN 0953-816X
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/ejn.14108
Author(s):
Hamid R. Noori, Lewis H. Mervin, Vahid Bokharaie, Özlem Durmus, Lisamon Egenrieder, Stefan Fritze, Britta Gruhlke, Giulia Reinhardt, Hans-Hendrik Schabel, Sabine Staudenmaier, Nikos K. Logothetis, Andreas Bender, Rainer Spanagel
Published in:
Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-018-07239-1
Author(s):
Silvia De Santis, David Moratal, Santiago Canals
Published in:
Neuroscience, 2017, ISSN 0306-4522
Publisher:
Elsevier BV
DOI:
10.1016/j.neuroscience.2017.11.055
Author(s):
Aref Pariz, Zahra G. Esfahani, Shervin S. Parsi, Alireza Valizadeh, Santiago Canals, Claudio R. Mirasso
Published in:
NeuroImage, Issue 166, 2018, Page(s) 349-359, ISSN 1053-8119
Publisher:
Academic Press
DOI:
10.1016/j.neuroimage.2017.11.014
Author(s):
Stefanie Uhrig, David Vandael, Andrea Marcantoni, Nina Dedic, Ainhoa Bilbao, Miriam A Vogt, Natalie Hirth, Laura Broccoli, Rick E Bernardi, Kai Schönig, Peter Gass, Dusan Bartsch, Rainer Spanagel, Jan M Deussing, Wolfgang H Sommer, Emilio Carbone, Anita C Hansson
Published in:
Neuropsychopharmacology, 2016, ISSN 0893-133X
Publisher:
Nature Publishing Group
DOI:
10.1038/npp.2016.266
Author(s):
Patrick Bach, Georg Weil, Enrico Pompili, Sabine Hoffmann, Derik Hermann, Sabine Vollstädt-Klein, Karl Mann, Ursula Perez-Ramirez, David Moratal, Santiago Canals, Serdar M. Dursun, Andrew J. Greenshaw, Peter Kirsch, Falk Kiefer, Wolfgang H. Sommer
Published in:
Addiction Biology, 2019, ISSN 1355-6215
Publisher:
Taylor & Francis
DOI:
10.1111/adb.12717
Author(s):
Silvia De Santis, Patrick Bach, Laura Pérez-Cervera, Alejandro Cosa-Linan, Georg Weil, Sabine Vollstädt-Klein, Derik Hermann, Falk Kiefer, Peter Kirsch, Roberto Ciccocioppo, Wolfgang H. Sommer, Santiago Canals
Published in:
JAMA Psychiatry, 2019, ISSN 2168-622X
Publisher:
American Medical Association
DOI:
10.1001/jamapsychiatry.2019.0318
Author(s):
Giulia Scuppa, Stefano Tambalo, Simone Pfarr, Wolfgang H. Sommer, Angelo Bifone
Published in:
Addiction Biology, 2019, ISSN 1355-6215
Publisher:
Taylor & Francis
DOI:
10.1111/adb.12744
Author(s):
Giampiero Bardella, Angelo Bifone, Andrea Gabrielli, Alessandro Gozzi, Tiziano Squartini
Published in:
Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/srep32060
Author(s):
Carlo Nicolini, Cécile Bordier, Angelo Bifone
Published in:
NeuroImage, Issue 146, 2017, Page(s) 28-39, ISSN 1053-8119
Publisher:
Academic Press
DOI:
10.1016/j.neuroimage.2016.11.026
Author(s):
Markus Heilig, Eric Augier, Simone Pfarr, Wolfgang H. Sommer
Published in:
Translational Psychiatry, Issue 9/1, 2019, ISSN 2158-3188
Publisher:
Nature Publishing Group
DOI:
10.1038/s41398-019-0591-6
Author(s):
Silvia De Santis, Wolfgang H. Sommer, Santiago Canals
Published in:
ACS Chemical Neuroscience, Issue 10/10, 2019, Page(s) 4187-4189, ISSN 1948-7193
Publisher:
American Chemical Society
DOI:
10.1021/acschemneuro.9b00481
Author(s):
Sandro Vega-Pons, Emanuele Olivetti, Paolo Avesani, Luca Dodero, Alessandro Gozzi, Angelo Bifone
Published in:
Frontiers in Neuroscience, Issue 10, 2017, ISSN 1662-453X
Publisher:
Frontiers in Neuroscience
DOI:
10.3389/fnins.2016.00605
Author(s):
Víctor J. López-Madrona, Fernanda S. Matias, Ernesto Pereda, Santiago Canals, Claudio R. Mirasso
Published in:
Chaos: An Interdisciplinary Journal of Nonlinear Science, Issue 27/4, 2017, Page(s) 047401, ISSN 1054-1500
Publisher:
American Institute of Physics
DOI:
10.1063/1.4979001
Author(s):
Ovidiu F. Jurjuţ, Medorian Gheorghiu, Wolf Singer, Danko Nikolić, Raul C. Mureşan
Published in:
Frontiers in Systems Neuroscience, Issue 13, 2019, ISSN 1662-5137
Publisher:
Frontiers Research Foundation
DOI:
10.3389/fnsys.2019.00021
Author(s):
Lisamon Egenrieder, Ekaterina Mitricheva, Rainer Spanagel, Hamid R. Noori
Published in:
Journal of Neurochemistry, 2019, ISSN 0022-3042
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/jnc.14911
Author(s):
Ciuparu A., Nagy-Dăbâcan A., Muresan R.C.
Published in:
Neurocomputing, 2020, ISSN 0925-2312
Publisher:
Elsevier BV
Author(s):
Irene Perini, Robin Kämpe, Theodor Arlestig, Hanna Karlsson, Andreas Löfberg, Michal Pietrzak, Abraham Zangen, Markus Heilig
Published in:
Neuropsychopharmacology, 2019, ISSN 0893-133X
Publisher:
Nature Publishing Group
DOI:
10.1038/s41386-019-0565-7
Author(s):
Christina Dinter, Derik Hermann, Judith Heckmann, Holger Hill, Iris Reinhard, Sabine Vollstädt‐Klein, Peter Kirsch, Falk Kiefer
Published in:
Addiction Biology, Issue 25/1, 2019, ISSN 1355-6215
Publisher:
Taylor & Francis
DOI:
10.1111/adb.12712
Author(s):
Dongmei Shi, Anna Levina, Hamid R. Noori
Published in:
Physical Review E, Issue 100/1, 2019, ISSN 2470-0045
Publisher:
Phys Rev E.
DOI:
10.1103/physreve.100.012301
Author(s):
Ekaterina Mitricheva, Rui Kimura, Nikos K. Logothetis, Hamid R. Noori
Published in:
Proceedings of the National Academy of Sciences, Issue 116/31, 2019, Page(s) 15671-15676, ISSN 0027-8424
Publisher:
National Academy of Sciences
DOI:
10.1073/pnas.1904975116
Author(s):
Răzvan Gămănuţ, Henry Kennedy, Zoltán Toroczkai, Mária Ercsey-Ravasz, David C. Van Essen, Kenneth Knoblauch, Andreas Burkhalter
Published in:
Neuron, Issue 97/3, 2018, Page(s) 698-715.e10, ISSN 0896-6273
Publisher:
Cell Press
DOI:
10.1016/j.neuron.2017.12.037
Author(s):
Martin Fungisai Gerchen, Alena Rentsch, Martina Kirsch, Falk Kiefer, Peter Kirsch
Published in:
Addiction Biology, Issue 24/6, 2018, Page(s) 1245-1253, ISSN 1355-6215
Publisher:
Taylor & Francis
DOI:
10.1111/adb.12692
Author(s):
Franziska Weiss, Vera Zamoscik, Stephanie N.L. Schmidt, Patrick Halli, Peter Kirsch, Martin Fungisai Gerchen
Published in:
NeuroImage, Issue 210, 2020, Page(s) 116580, ISSN 1053-8119
Publisher:
Academic Press
DOI:
10.1016/j.neuroimage.2020.116580
Author(s):
Stefano Tambalo, Giulia Scuppa, Angelo Bifone
Published in:
Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-018-37863-2
Author(s):
Patrick Bach, Anne Koopmann, Jan Malte Bumb, Sina Zimmermann, Sina Bühler, Iris Reinhard, Stephanie H. Witt, Marcella Rietschel, Sabine Vollstädt-Klein, Falk Kiefer
Published in:
European Archives of Psychiatry and Clinical Neuroscience, 2020, ISSN 0940-1334
Publisher:
Dr. Dietrich Steinkopff Verlag
DOI:
10.1007/s00406-020-01115-0
Author(s):
Hamid R. Noori, Judith Schöttler, Maria Ercsey-Ravasz, Alejandro Cosa-Linan, Melinda Varga, Zoltan Toroczkai, Rainer Spanagel
Published in:
PLOS Biology, Issue 15/7, 2017, Page(s) e2002612, ISSN 1545-7885
Publisher:
PLoS Biol
DOI:
10.1371/journal.pbio.2002612
Author(s):
Antonio Díaz-Parra, Zachary Osborn, Santiago Canals, David Moratal, Olaf Sporns
Published in:
NeuroImage, Issue 159, 2017, Page(s) 170-184, ISSN 1053-8119
Publisher:
Academic Press
DOI:
10.1016/j.neuroimage.2017.07.046
Author(s):
Derik Hermann, Natalie Hirth, Matthias Reimold, Anil Batra, Michael N Smolka, Sabine Hoffmann, Falk Kiefer, Hamid R Noori, Wolfgang H Sommer, Gerald Reischl, Christian la Fougère, Karl Mann, Rainer Spanagel, Anita C Hansson
Published in:
Neuropsychopharmacology, Issue 42/3, 2016, Page(s) 606-614, ISSN 0893-133X
Publisher:
Nature Publishing Group
DOI:
10.1038/npp.2016.145
Author(s):
Vladimir Vlasov, Angelo Bifone
Published in:
Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-017-09887-7
Author(s):
Mia Haaranen, Giulia Scuppa, Stefano Tambalo, Vilja Järvi, Sine M. Bertozzi, Andrea Armirotti, Wolfgang H. Sommer, Angelo Bifone, Petri Hyytiä
Published in:
Translational Psychiatry, Issue 10/1, 2020, ISSN 2158-3188
Publisher:
Nature Publishing Group
DOI:
10.1038/s41398-020-0833-7
Author(s):
Silvia De Santis, Alejandro Cosa-Linan, Raquel Garcia-Hernandez, Lesia Dmytrenko, Lydia Vargova, Ivan Vorisek, Serena Stopponi, Patrick Bach, Peter Kirsch, Falk Kiefer, Roberto Ciccocioppo, Eva Sykova, David Moratal, Wolfgang H. Sommer, Santiago Canals
Published in:
Science Advances, Issue 6/26, 2020, Page(s) eaba0154, ISSN 2375-2548
Publisher:
SCIENCE ADVANCES
DOI:
10.1126/sciadv.aba0154
Author(s):
Darío R Quiñones, Luis Miguel Fernández-Mollá, Jesús Pacheco-Torres, José M Caramés, Santiago Canals, David Moratal
Published in:
Magnetic Resonance Imaging, 2019, ISSN 0730-725x
Publisher:
Elsevier BV
DOI:
10.1016/j.mri.2019.01.009
Author(s):
Laura Pérez-Cervera, José María Caramés, Luis Miguel Fernández-Mollá, Andrea Moreno, Begoña Fernández, Elena Pérez-Montoyo, David Moratal, Santiago Canals, Jesús Pacheco-Torres
Published in:
Preclinical MRI, Issue 1718, 2018, Page(s) 117-134, ISBN 978-1-4939-7530-3
Publisher:
Springer New York
DOI:
10.1007/978-1-4939-7531-0_8
Author(s):
Fathizadeh, F.; Mitricheva, E.; Kimura, R.; Logothetis, N.; Noori, H.
Published in:
Issue 5, 2019
Publisher:
arXiv
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