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Understanding asthma phenotypes: going beyond the atopic/non-atopic paradigm

Publications

Causal Inference in Environmental Epidemiology: Old and New Approaches

Author(s): Neil Pearce, Jan P. Vandenbroucke, Deborah A. Lawlor
Published in: Epidemiology, 30/3, 2019, Page(s) 311-316, ISSN 1044-3983
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/ede.0000000000000987

Comparison of individual-level and population-level risk factors for rhinoconjunctivitis, asthma, and eczema in the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three

Author(s): Charlotte E. Rutter, Richard J. Silverwood, M.Innes Asher, Philippa Ellwood, Neil Pearce, Luis Garcia-Marcos, David P. Strachan
Published in: World Allergy Organization Journal, 13/6, 2020, Page(s) 100123, ISSN 1939-4551
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.waojou.2020.100123

Anxiety disorders and asthma among adolescents in Uganda: role of early-life exposures

Author(s): Harriet Mpairwe, Richard Stephen Mpango, Wilber Sembajjwe, Emily L. Webb, Alison M. Elliott, Neil Pearce, Eugene Kinyanda
Published in: ERJ Open Research, 7/2, 2021, Page(s) 00749-2020, ISSN 2312-0541
Publisher: European Respiratory Society
DOI: 10.1183/23120541.00749-2020

Evidence for causal associations between prenatal and postnatal antibiotic exposure and asthma in children, England

Author(s): Sergio Souza da Cunha, Gillian Santorelli, Neil Pearce, John Wright, Sam Oddie, Emily Petherick, Lucy Pembrey
Published in: Clinical & Experimental Allergy, 51/11, 2021, Page(s) 1438-1448, ISSN 0954-7894
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cea.13999

Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?

Author(s): Richard J. Silverwood, Charlotte E. Rutter, Edwin A. Mitchell, M. Innes Asher, Luis Garcia‐Marcos, David P. Strachan, Neil Pearce, N Aït‐Khaled, HR Anderson, R Beasley, B Björkstén, B Brunekreef, J Crane, P Ellwood, C Flohr, F Forastiere, S Foliaki, U Keil, CKW Lai, J Mallol, CF Robertson, S Montefort, J Odhiambo, J Shah, AW Stewart, D Strachan, E Mutius, SK Weiland, G Weinmayr, G Wong, TO
Published in: Clinical & Experimental Allergy, 49/4, 2019, Page(s) 430-441, ISSN 0954-7894
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cea.13325

Worldwide time trends in prevalence of symptoms of rhinoconjunctivitis in children: Global Asthma Network Phase I

Author(s): David P. Strachan, Charlotte E. Rutter, Monica Innes Asher, Karen Bissell, Chen‐Yuan Chiang, Asma El Sony, Eamon Ellwood, Philippa Ellwood, Luis García‐Marcos, Guy B. Marks, Eva Morales, Kevin Mortimer, Neil Pearce, Virginia Pérez‐Fernández, Steven Robertson, Richard J. Silverwood, EM Navarrete‐Rodriguez, A López‐Silvarrey Varela, MI Asher, K Bissell, C‐Y Chiang, A El Sony, P Ellwo
Published in: Pediatric Allergy and Immunology, 2021, ISSN 0905-6157
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pai.13656

Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink)

Author(s): Francis Nissen, Ian J. Douglas, Hana Müllerová, Neil Pearce, Chloe Bloom, Liam Smeeth, Jennifer K. Quint
Published in: Journal of Asthma and Allergy, Volume 12, 2019, Page(s) 7-19, ISSN 1178-6965
Publisher: Dove Medical Press Ltd
DOI: 10.2147/jaa.s182013

Association between mode of delivery and body mass index at 4-5 years in White British and Pakistani children: the Born in Bradford birth cohort

Author(s): Eleanor Ralphs, Lucy Pembrey, Jane West, Gillian Santorelli
Published in: BMC Public Health, 21/1, 2021, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/s12889-021-11009-y

Age at cytomegalovirus, Epstein Barr virus and varicella zoster virus infection and risk of atopy: the Born in Bradford cohort, UK

Author(s): Lucy Pembrey, Dagmar Waiblinger, Paul Griffiths, John Wright
Published in: Pediatric Allergy and Immunology, 2019, ISSN 0905-6157
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pai.13093

Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Author(s): M Innes Asher, Charlotte E Rutter, K Bissell, Chen-Yuan Chiang, Asma El Sony, Eamon Ellwood, Philippa Ellwood, Luis García-Marcos, Guy B Marks, Eva Morales, Kevin Mortimer, Virginia Pérez-Fernández, Steven Robertson, Richard J Silverwood, David P Strachan, Neil Pearce, Karen Bissell, Chen-Yuan Chiang, Eamon Ellwood, Philippa Ellwood, Guy B Marks, Refiloe Masekela, Eva Morales, Kevin Mortimer, N
Published in: The Lancet, 398/10311, 2021, Page(s) 1569-1580, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(21)01450-1

Are Environmental Factors for Atopic Eczema in ISAAC Phase Three due to Reverse Causation?

Author(s): Charlotte E. Rutter, Richard J. Silverwood, Hywel C. Williams, Philippa Ellwood, Innes Asher, Luis Garcia-Marcos, David P. Strachan, Neil Pearce, Sinéad M. Langan, N. Aït-Khaled, H.R. Anderson, M.I. Asher, R. Beasley, B. Björkstén, B. Brunekreef, J. Crane, P. Ellwood, C. Flohr, S. Foliaki, F. Forastiere, L. García-Marcos, U. Keil, C.K.W. Lai, J. Mallol, E.A. Mitchell, S. Montefort, J. Odhiamb
Published in: Journal of Investigative Dermatology, 139/5, 2019, Page(s) 1023-1036, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/J.JID.2018.08.035

Cancer subtypes in aetiological research

Author(s): Lorenzo Richiardi, Francesco Barone-Adesi, Neil Pearce
Published in: European Journal of Epidemiology, 32/5, 2017, Page(s) 353-361, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-017-0253-z

Bias in matched case–control studies: DAGs are not enough

Author(s): Neil Pearce
Published in: European Journal of Epidemiology, 33/1, 2018, Page(s) 1-4, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-018-0362-3

From ideas to studies: how to get ideas and sharpen them into research questions

Author(s): Jan P Vandenbroucke, Neil Pearce
Published in: Clinical Epidemiology, Volume 10, 2018, Page(s) 253-264, ISSN 1179-1349
Publisher: Dove Medical Press Ltd
DOI: 10.2147/CLEP.S142940

Causal inference—so much more than statistics

Author(s): Neil Pearce, Debbie A Lawlor
Published in: International Journal of Epidemiology, 45/6, 2016, Page(s) 1895-1903, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyw328

Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration

Author(s): Lucy Pembrey, Mauricio L. Barreto, Jeroen Douwes, Philip Cooper, John Henderson, Harriet Mpairwe, Cristina Ardura-Garcia, Martha Chico, Collin Brooks, Alvaro A. Cruz, Alison M. Elliott, Camila A. Figueiredo, Sinéad M. Langan, Beatrice Nassanga, Susan Ring, Laura Rodrigues, Neil Pearce
Published in: ERJ Open Research, 4/3, 2018, Page(s) 00013-2018, ISSN 2312-0541
Publisher: ERS Publications
DOI: 10.1183/23120541.00013-2018

Baseline selection on a collider: a ubiquitous mechanism occurring in both representative and selected cohort studies

Author(s): Lorenzo Richiardi, Neil Pearce, Eva Pagano, Daniela Di Cuonzo, Daniela Zugna, Costanza Pizzi
Published in: Journal of Epidemiology and Community Health, 2019, Page(s) jech-2018-211829, ISSN 0143-005X
Publisher: British Medical Association
DOI: 10.1136/jech-2018-211829

Classifying atopic dermatitis: protocol for a systematic review of subtypes (phenotypes) and associated characteristics

Author(s): Amy R Mulick, Victoria Allen, Hywel C Williams, Douglas J C Grindlay, Neil Pearce, Katrina Abuabara, Sinéad M Langan
Published in: BMJ Open, 8/9, 2018, Page(s) e023097, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2018-023097

Outcome modelling strategies in epidemiology: traditional methods and basic alternatives

Author(s): Sander Greenland, Rhian Daniel, Neil Pearce
Published in: International Journal of Epidemiology, 45/2, 2016, Page(s) 565-575, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyw040

Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

Author(s): Harriet Mpairwe, Milly Namutebi, Gyaviira Nkurunungi, Pius Tumwesige, Irene Nambuya, Mike Mukasa, Caroline Onen, Marble Nnaluwooza, Barbara Apule, Tonny Katongole, Gloria Oduru, Joseph Kahwa, Emily L Webb, Lawrence Lubyayi, Neil Pearce, Alison M Elliott
Published in: eLife, 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.49496

Test-Negative Designs

Author(s): Jan P. Vandenbroucke, Neil Pearce
Published in: Epidemiology, 30/6, 2019, Page(s) 838-844, ISSN 1044-3983
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/ede.0000000000001088

Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort

Author(s): A.R. Mulick, K.E. Mansfield, R.J. Silverwood, A. Budu‐Aggrey, A. Roberts, A. Custovic, N. Pearce, A.D. Irvine, L. Smeeth, K. Abuabara, S.M. Langan
Published in: British Journal of Dermatology, 185/3, 2021, Page(s) 526-536, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.19885

Asthma control and management among schoolchildren in urban Uganda: results from a cross-sectional study

Author(s): Harriet Mpairwe, Pius Tumwesige, Milly Namutebi, Marble Nnaluwooza, Tonny Katongole, Josephine Tumusiime, Barbara Apule, Caroline Onen, Mike Mukasa, Joseph Kahwa, Emily L. Webb, Neil Pearce, Alison M. Elliott
Published in: Wellcome Open Research, 4, 2019, Page(s) 168, ISSN 2398-502X
Publisher: Wellcome Open Research
DOI: 10.12688/wellcomeopenres.15460.1

Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda

Author(s): Harriet Mpairwe, Gyaviira Nkurunungi, Pius Tumwesige, Hellen Akurut, Milly Namutebi, Irene Nambuya, Marble Nnaluwooza, Barbara Apule, Caroline Onen, Tonny Katongole, Emmanuel Niwagaba, Mike Mukasa, Emily L. Webb, Alison M. Elliott, Neil Pearce
Published in: Clinical & Experimental Allergy, 51/1, 2021, Page(s) 108-119, ISSN 0954-7894
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cea.13769

The Global Asthma Network

Author(s): Asher I, Billo N, Bissell K, Chen-Yuan C, Ellwood P, El Sony A, Garcia-Marcos L, Marks G, Pearce N, Strachan D
Published in: The Global Asthma Report, 2018 (Publication date: 31/8/18), 2018, Page(s) 12-13
Publisher: The Global Asthma Network

Asthma as an NCD priority

Author(s): Pearce N, Mallol J, El Sony A, Marks G
Published in: The Global Asthma Report, 2018 (Pub: 31/8/18), 2018, Page(s) 74-76
Publisher: The Global Asthma Network

Factors affecting asthma

Author(s): Garcia-Marcos L, Pearce N, Strachan D, Silverwood R, Rutter C, Elwood E
Published in: The Global Asthma Report, 2018 (Pub: 31/8/18), 2018, Page(s) 35-37
Publisher: The Global Asthma Network

Global burden of disease due to asthma

Author(s): Marks G, Pearce N, Strachan D, Asher I, Elwood P
Published in: The Global Asthma Report, 2018 (Pub: 31/8/18), 2018, Page(s) 18-21
Publisher: The Global Asthma Network

What is asthma?

Author(s): Asher I, Pearce N, Strachan D, Billo N, Chen-Yuang C, Ellwood P, El Sony A, Garcia-Maracos L, Marks G
Published in: The Global Asthma Report, 2018 (Publication: 31/8/18), 2018, Page(s) 16-17
Publisher: Global Asthma Network

Asthma mortality

Author(s): Strachan D, Limb E, Pearce N, Marks G, Morales E, Perez-Fernandez V
Published in: The Global Asthma Report, 2018 (Pub: 31/8/18), 2018, Page(s) 27-31
Publisher: The Global Asthma Network

Asthma inflammatory phenotypes on four continents

Author(s): Pembrey L, Brooks CR, Mpairwe H, Figueiredo CA, Chico M, Nambuya I, Tumwesige P, Robertson S, Ring R, Barreto ML, Cooper PJ, Henderson J, Cruz AA, Douwes J, Pearce N.
Published in: medRxiv 2020, 2020
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.08.23.20177162

Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

Author(s): Harriet Mpairwe; Milly Namutebi; Gyaviira Nkurunungi; Pius Tumwesige; Irene Nambuya; Mike Mukasa; Caroline Onen; Marble Nnaluwooza; Barbara Apule; Tonny Katongole; Gloria Oduru; Joseph Kahwa; Emily L Webb; Lawrence Lubyayi; Neil Pearce; Alison M Elliott
Published in: eLife, 4, 2019
Publisher: elifes Sciences Publications Ltd
DOI: 10.1101/677799