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Understanding asthma phenotypes: going beyond the atopic/non-atopic paradigm

Publications

Causal Inference in Environmental Epidemiology: Old and New Approaches

Auteurs: Neil Pearce, Jan P. Vandenbroucke, Deborah A. Lawlor
Publié dans: Epidemiology, Numéro 30/3, 2019, Page(s) 311-316, ISSN 1044-3983
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/ede.0000000000000987

Comparison of individual-level and population-level risk factors for rhinoconjunctivitis, asthma, and eczema in the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three

Auteurs: Charlotte E. Rutter, Richard J. Silverwood, M.Innes Asher, Philippa Ellwood, Neil Pearce, Luis Garcia-Marcos, David P. Strachan
Publié dans: World Allergy Organization Journal, Numéro 13/6, 2020, Page(s) 100123, ISSN 1939-4551
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.waojou.2020.100123

Anxiety disorders and asthma among adolescents in Uganda: role of early-life exposures

Auteurs: Harriet Mpairwe, Richard Stephen Mpango, Wilber Sembajjwe, Emily L. Webb, Alison M. Elliott, Neil Pearce, Eugene Kinyanda
Publié dans: ERJ Open Research, Numéro 7/2, 2021, Page(s) 00749-2020, ISSN 2312-0541
Éditeur: European Respiratory Society
DOI: 10.1183/23120541.00749-2020

Evidence for causal associations between prenatal and postnatal antibiotic exposure and asthma in children, England

Auteurs: Sergio Souza da Cunha, Gillian Santorelli, Neil Pearce, John Wright, Sam Oddie, Emily Petherick, Lucy Pembrey
Publié dans: Clinical & Experimental Allergy, Numéro 51/11, 2021, Page(s) 1438-1448, ISSN 0954-7894
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cea.13999

Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?

Auteurs: Richard J. Silverwood, Charlotte E. Rutter, Edwin A. Mitchell, M. Innes Asher, Luis Garcia‐Marcos, David P. Strachan, Neil Pearce, N Aït‐Khaled, HR Anderson, R Beasley, B Björkstén, B Brunekreef, J Crane, P Ellwood, C Flohr, F Forastiere, S Foliaki, U Keil, CKW Lai, J Mallol, CF Robertson, S Montefort, J Odhiambo, J Shah, AW Stewart, D Strachan, E Mutius, SK Weiland, G Weinmayr, G Wong, TO
Publié dans: Clinical & Experimental Allergy, Numéro 49/4, 2019, Page(s) 430-441, ISSN 0954-7894
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cea.13325

Worldwide time trends in prevalence of symptoms of rhinoconjunctivitis in children: Global Asthma Network Phase I

Auteurs: David P. Strachan, Charlotte E. Rutter, Monica Innes Asher, Karen Bissell, Chen‐Yuan Chiang, Asma El Sony, Eamon Ellwood, Philippa Ellwood, Luis García‐Marcos, Guy B. Marks, Eva Morales, Kevin Mortimer, Neil Pearce, Virginia Pérez‐Fernández, Steven Robertson, Richard J. Silverwood, EM Navarrete‐Rodriguez, A López‐Silvarrey Varela, MI Asher, K Bissell, C‐Y Chiang, A El Sony, P Ellwo
Publié dans: Pediatric Allergy and Immunology, 2021, ISSN 0905-6157
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/pai.13656

Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink)

Auteurs: Francis Nissen, Ian J. Douglas, Hana Müllerová, Neil Pearce, Chloe Bloom, Liam Smeeth, Jennifer K. Quint
Publié dans: Journal of Asthma and Allergy, Numéro Volume 12, 2019, Page(s) 7-19, ISSN 1178-6965
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/jaa.s182013

Association between mode of delivery and body mass index at 4-5 years in White British and Pakistani children: the Born in Bradford birth cohort

Auteurs: Eleanor Ralphs, Lucy Pembrey, Jane West, Gillian Santorelli
Publié dans: BMC Public Health, Numéro 21/1, 2021, ISSN 1471-2458
Éditeur: BioMed Central
DOI: 10.1186/s12889-021-11009-y

Age at cytomegalovirus, Epstein Barr virus and varicella zoster virus infection and risk of atopy: the Born in Bradford cohort, UK

Auteurs: Lucy Pembrey, Dagmar Waiblinger, Paul Griffiths, John Wright
Publié dans: Pediatric Allergy and Immunology, 2019, ISSN 0905-6157
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/pai.13093

Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Auteurs: M Innes Asher, Charlotte E Rutter, K Bissell, Chen-Yuan Chiang, Asma El Sony, Eamon Ellwood, Philippa Ellwood, Luis García-Marcos, Guy B Marks, Eva Morales, Kevin Mortimer, Virginia Pérez-Fernández, Steven Robertson, Richard J Silverwood, David P Strachan, Neil Pearce, Karen Bissell, Chen-Yuan Chiang, Eamon Ellwood, Philippa Ellwood, Guy B Marks, Refiloe Masekela, Eva Morales, Kevin Mortimer, N
Publié dans: The Lancet, Numéro 398/10311, 2021, Page(s) 1569-1580, ISSN 0140-6736
Éditeur: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(21)01450-1

Are Environmental Factors for Atopic Eczema in ISAAC Phase Three due to Reverse Causation?

Auteurs: Charlotte E. Rutter, Richard J. Silverwood, Hywel C. Williams, Philippa Ellwood, Innes Asher, Luis Garcia-Marcos, David P. Strachan, Neil Pearce, Sinéad M. Langan, N. Aït-Khaled, H.R. Anderson, M.I. Asher, R. Beasley, B. Björkstén, B. Brunekreef, J. Crane, P. Ellwood, C. Flohr, S. Foliaki, F. Forastiere, L. García-Marcos, U. Keil, C.K.W. Lai, J. Mallol, E.A. Mitchell, S. Montefort, J. Odhiamb
Publié dans: Journal of Investigative Dermatology, Numéro 139/5, 2019, Page(s) 1023-1036, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/J.JID.2018.08.035

Cancer subtypes in aetiological research

Auteurs: Lorenzo Richiardi, Francesco Barone-Adesi, Neil Pearce
Publié dans: European Journal of Epidemiology, Numéro 32/5, 2017, Page(s) 353-361, ISSN 0393-2990
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10654-017-0253-z

Bias in matched case–control studies: DAGs are not enough

Auteurs: Neil Pearce
Publié dans: European Journal of Epidemiology, Numéro 33/1, 2018, Page(s) 1-4, ISSN 0393-2990
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10654-018-0362-3

From ideas to studies: how to get ideas and sharpen them into research questions

Auteurs: Jan P Vandenbroucke, Neil Pearce
Publié dans: Clinical Epidemiology, Numéro Volume 10, 2018, Page(s) 253-264, ISSN 1179-1349
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/CLEP.S142940

Causal inference—so much more than statistics

Auteurs: Neil Pearce, Debbie A Lawlor
Publié dans: International Journal of Epidemiology, Numéro 45/6, 2016, Page(s) 1895-1903, ISSN 0300-5771
Éditeur: Oxford University Press
DOI: 10.1093/ije/dyw328

Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration

Auteurs: Lucy Pembrey, Mauricio L. Barreto, Jeroen Douwes, Philip Cooper, John Henderson, Harriet Mpairwe, Cristina Ardura-Garcia, Martha Chico, Collin Brooks, Alvaro A. Cruz, Alison M. Elliott, Camila A. Figueiredo, Sinéad M. Langan, Beatrice Nassanga, Susan Ring, Laura Rodrigues, Neil Pearce
Publié dans: ERJ Open Research, Numéro 4/3, 2018, Page(s) 00013-2018, ISSN 2312-0541
Éditeur: ERS Publications
DOI: 10.1183/23120541.00013-2018

Baseline selection on a collider: a ubiquitous mechanism occurring in both representative and selected cohort studies

Auteurs: Lorenzo Richiardi, Neil Pearce, Eva Pagano, Daniela Di Cuonzo, Daniela Zugna, Costanza Pizzi
Publié dans: Journal of Epidemiology and Community Health, 2019, Page(s) jech-2018-211829, ISSN 0143-005X
Éditeur: British Medical Association
DOI: 10.1136/jech-2018-211829

Classifying atopic dermatitis: protocol for a systematic review of subtypes (phenotypes) and associated characteristics

Auteurs: Amy R Mulick, Victoria Allen, Hywel C Williams, Douglas J C Grindlay, Neil Pearce, Katrina Abuabara, Sinéad M Langan
Publié dans: BMJ Open, Numéro 8/9, 2018, Page(s) e023097, ISSN 2044-6055
Éditeur: BMJ Publishing Group
DOI: 10.1136/bmjopen-2018-023097

Outcome modelling strategies in epidemiology: traditional methods and basic alternatives

Auteurs: Sander Greenland, Rhian Daniel, Neil Pearce
Publié dans: International Journal of Epidemiology, Numéro 45/2, 2016, Page(s) 565-575, ISSN 0300-5771
Éditeur: Oxford University Press
DOI: 10.1093/ije/dyw040

Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

Auteurs: Harriet Mpairwe, Milly Namutebi, Gyaviira Nkurunungi, Pius Tumwesige, Irene Nambuya, Mike Mukasa, Caroline Onen, Marble Nnaluwooza, Barbara Apule, Tonny Katongole, Gloria Oduru, Joseph Kahwa, Emily L Webb, Lawrence Lubyayi, Neil Pearce, Alison M Elliott
Publié dans: eLife, Numéro 8, 2019, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.49496

Test-Negative Designs

Auteurs: Jan P. Vandenbroucke, Neil Pearce
Publié dans: Epidemiology, Numéro 30/6, 2019, Page(s) 838-844, ISSN 1044-3983
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/ede.0000000000001088

Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort

Auteurs: A.R. Mulick, K.E. Mansfield, R.J. Silverwood, A. Budu‐Aggrey, A. Roberts, A. Custovic, N. Pearce, A.D. Irvine, L. Smeeth, K. Abuabara, S.M. Langan
Publié dans: British Journal of Dermatology, Numéro 185/3, 2021, Page(s) 526-536, ISSN 0007-0963
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/bjd.19885

Asthma control and management among schoolchildren in urban Uganda: results from a cross-sectional study

Auteurs: Harriet Mpairwe, Pius Tumwesige, Milly Namutebi, Marble Nnaluwooza, Tonny Katongole, Josephine Tumusiime, Barbara Apule, Caroline Onen, Mike Mukasa, Joseph Kahwa, Emily L. Webb, Neil Pearce, Alison M. Elliott
Publié dans: Wellcome Open Research, Numéro 4, 2019, Page(s) 168, ISSN 2398-502X
Éditeur: Wellcome Open Research
DOI: 10.12688/wellcomeopenres.15460.1

Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda

Auteurs: Harriet Mpairwe, Gyaviira Nkurunungi, Pius Tumwesige, Hellen Akurut, Milly Namutebi, Irene Nambuya, Marble Nnaluwooza, Barbara Apule, Caroline Onen, Tonny Katongole, Emmanuel Niwagaba, Mike Mukasa, Emily L. Webb, Alison M. Elliott, Neil Pearce
Publié dans: Clinical & Experimental Allergy, Numéro 51/1, 2021, Page(s) 108-119, ISSN 0954-7894
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cea.13769

The Global Asthma Network

Auteurs: Asher I, Billo N, Bissell K, Chen-Yuan C, Ellwood P, El Sony A, Garcia-Marcos L, Marks G, Pearce N, Strachan D
Publié dans: The Global Asthma Report, Numéro 2018 (Publication date: 31/8/18), 2018, Page(s) 12-13
Éditeur: The Global Asthma Network

Asthma as an NCD priority

Auteurs: Pearce N, Mallol J, El Sony A, Marks G
Publié dans: The Global Asthma Report, Numéro 2018 (Pub: 31/8/18), 2018, Page(s) 74-76
Éditeur: The Global Asthma Network

Factors affecting asthma

Auteurs: Garcia-Marcos L, Pearce N, Strachan D, Silverwood R, Rutter C, Elwood E
Publié dans: The Global Asthma Report, Numéro 2018 (Pub: 31/8/18), 2018, Page(s) 35-37
Éditeur: The Global Asthma Network

Global burden of disease due to asthma

Auteurs: Marks G, Pearce N, Strachan D, Asher I, Elwood P
Publié dans: The Global Asthma Report, Numéro 2018 (Pub: 31/8/18), 2018, Page(s) 18-21
Éditeur: The Global Asthma Network

What is asthma?

Auteurs: Asher I, Pearce N, Strachan D, Billo N, Chen-Yuang C, Ellwood P, El Sony A, Garcia-Maracos L, Marks G
Publié dans: The Global Asthma Report, Numéro 2018 (Publication: 31/8/18), 2018, Page(s) 16-17
Éditeur: Global Asthma Network

Asthma mortality

Auteurs: Strachan D, Limb E, Pearce N, Marks G, Morales E, Perez-Fernandez V
Publié dans: The Global Asthma Report, Numéro 2018 (Pub: 31/8/18), 2018, Page(s) 27-31
Éditeur: The Global Asthma Network

Asthma inflammatory phenotypes on four continents

Auteurs: Pembrey L, Brooks CR, Mpairwe H, Figueiredo CA, Chico M, Nambuya I, Tumwesige P, Robertson S, Ring R, Barreto ML, Cooper PJ, Henderson J, Cruz AA, Douwes J, Pearce N.
Publié dans: medRxiv 2020, 2020
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.08.23.20177162

Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

Auteurs: Harriet Mpairwe; Milly Namutebi; Gyaviira Nkurunungi; Pius Tumwesige; Irene Nambuya; Mike Mukasa; Caroline Onen; Marble Nnaluwooza; Barbara Apule; Tonny Katongole; Gloria Oduru; Joseph Kahwa; Emily L Webb; Lawrence Lubyayi; Neil Pearce; Alison M Elliott
Publié dans: eLife, Numéro 4, 2019
Éditeur: elifes Sciences Publications Ltd
DOI: 10.1101/677799

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