Objective Fathers have largely been neglected in parenting research -- although they constitute about 50% of parents. The aim of the proposed project is to test the hypothesis that fathers’ parenting is under hormonal control and can be changed by behavioral and hormonal interventions. I propose a series of randomized controlled trials (RCT) focusing on a critical phase of parenthood: the transition to having the first baby. I will test whether experiments that modulate oxytocin and testosterone levels enhance fathers’ neural processing of infant signals and of threats to the infant and stimulate fathers’ parenting quality and involvement in parenting. Drawing firm conclusions about the neural and hormonal basis of human parenting is critically dependent on RCTs. I propose two types of experiments: (1) within-subject trials, using nasal administration of oxytocin, testosterone, and a placebo, and (2) between-subject trials, using behavioral interventions aimed at promoting sensitive parenting and physical contact. The behavioral interventions include prenatal and postnatal video feedback intervention (in the prenatal phase based on ultrasound scans) and the use of soft baby carriers. Both types of trials take place 3 months before the infant’s birth, and 2 and 7 months afterwards.A special focus lies on the aspect of protection: a dimension of parenting that has received considerable attention in animal research but, despite its evolutionary importance, not in studies on humans. Testing the efficacy of the behavioral experiments in boosting fathers’ protective parenting and participation in caregiving activities has clear practical significance (for fathers, mothers, children, and society). At the same time, examining the hormonal and neural mechanisms is crucial for the development of theory on the interplay between neuroscience and parenting. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesbiological sciencesbiochemistrybiomoleculessocial sciencespolitical sciencespublic administrationbureaucracymedical and health sciencesclinical medicineobstetricsnatural sciencesphysical sciencesacousticsultrasound Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-ADG-2014 - ERC Advanced Grant Call for proposal ERC-2014-ADG See other projects for this call Funding Scheme ERC-ADG - Advanced Grant Coordinator STICHTING VU Net EU contribution € 1 721 992,61 Address De boelelaan 1105 1081 HV Amsterdam Netherlands See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Beneficiaries (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all STICHTING VU Netherlands Net EU contribution € 1 721 992,61 Address De boelelaan 1105 1081 HV Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITEIT LEIDEN Participation ended Netherlands Net EU contribution € 738 507,39 Address Rapenburg 70 2311 EZ Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00