Reactions That Translate mRNA into Drug-like Molecules

Project Information

TRIGGDRUG

Grant agreement ID: 669628

DOI

10.3030/669628

Project closed

EC signature date 24 July 2015

Start date 1 January 2016

End date 31 December 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 470 400,00

EU contribution

€ 2 470 400,00

Coordinated by

HUMBOLDT-UNIVERSITAET ZU BERLIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Expanding the scope of native chemical ligation - templated small molecule drug synthesis via benzanilide formation

Author(s): Richard Houska, Marvin Björn Stutz, Oliver Seitz
Published in: Chemical Science, 2021, ISSN 2041-6539
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1sc00513h

Toward conditional control of Smac mimetic activity by RNA‐templated reduction of azidopeptides on PNA or 2′‐ OMe‐RNA

Author(s): Yannic Altrichter, Justus Schöller, Oliver Seitz
Published in: Biopolymers, 2021, ISSN 0006-3525
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/bip.23466

RNA-templated chemical synthesis of proapoptotic L- and d-peptides

Author(s): Li-Hao Chang, Oliver Seitz
Published in: Bioorganic & Medicinal Chemistry, Issue 09680896, 2022, ISSN 0968-0896
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bmc.2022.116786

DNA-Templated Reactions with High Catalytic Efficiency Achieved by a Loss-of-Affinity Principle

Author(s): Dino Gluhacevic von Krüchten, Magdalena Roth, Oliver Seitz
Published in: Journal of the American Chemical Society, 2022, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c03188

Templated chemistry for bioorganic synthesis and chemical biology

Author(s): Oliver Seitz
Published in: Journal of Peptide Science, Issue 25/7, 2019, ISSN 1075-2617
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/psc.3198

Nucleic acid constructs for the interrogation of multivalent protein interactions

Author(s): Sean B. Yeldell, Oliver Seitz
Published in: Chemical Society Reviews, 2020, ISSN 0306-0012
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0cs00518e

Comparing Agent‐Based Delivery of DNA and PNA Forced Intercalation (FIT) Probes for Multicolor mRNA Imaging

Author(s): Jasmine Chamiolo, Ge‐min Fang, Felix Hövelmann, Dhana Friedrich, Andrea Knoll, Alexander Loewer, Oliver Seitz
Published in: ChemBioChem, 2018, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800526

Nucleic Acid Templated Reactions for Chemical Biology

Author(s): Margherita Di Pisa, Oliver Seitz
Published in: ChemMedChem, Issue 12/12, 2017, Page(s) 872-882, ISSN 1860-7179
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.201700266

Simultaneous Targeting of Two Master Regulators of Apoptosis with Dual-Action PNA– and DNA–Peptide Conjugates

Author(s): Yannic Altrichter, Oliver Seitz
Published in: Bioconjugate Chemistry, Issue 31/8, 2020, Page(s) 1928-1937, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.0c00284

A Self‐immolative Molecular Beacon for Amplified Nucleic Acid Detection**

Author(s): Magdalena Roth, Oliver Seitz
Published in: Chemistry – A European Journal, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202102600