Molecular reconstitution of epigenetic centromere inheritance

Project Information

RECEPIANCE

Grant agreement ID: 669686

DOI

10.3030/669686

Project closed

EC signature date 7 July 2015

Start date 1 August 2015

End date 31 July 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 064 583,00

EU contribution

€ 2 064 583,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (16)

CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading

Author(s): Dongqing Pan, Kerstin Klare, Arsen Petrovic, Annika Take, Kai Walstein, Priyanka Singh, Arnaud Rondelet, Alexander W Bird, Andrea Musacchio
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.23352

Structure of the RZZ complex and molecular basis of its interaction with Spindly

Author(s): Shyamal Mosalaganti, Jenny Keller, Anika Altenfeld, Michael Winzker, Pascaline Rombaut, Michael Saur, Arsen Petrovic, Annemarie Wehenkel, Sabine Wohlgemuth, Franziska Müller, Stefano Maffini, Tanja Bange, Franz Herzog, Herbert Waldmann, Stefan Raunser, Andrea Musacchio
Published in: The Journal of Cell Biology, Issue 216/4, 2017, Page(s) 961-981, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201611060

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics

Author(s): Andrea Musacchio
Published in: Current Biology, Issue 25/20, 2015, Page(s) R1002-R1018, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2015.08.051

Insights from biochemical reconstitution into the architecture of human kinetochores

Author(s): John R. Weir, Alex C. Faesen, Kerstin Klare, Arsen Petrovic, Federica Basilico, Josef Fischböck, Satyakrishna Pentakota, Jenny Keller, Marion E. Pesenti, Dongqing Pan, Doro Vogt, Sabine Wohlgemuth, Franz Herzog, Andrea Musacchio
Published in: Nature, Issue 537/7619, 2016, Page(s) 249-253, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature19333

Basis of catalytic assembly of the mitotic checkpoint complex

Author(s): Alex C. Faesen, Maria Thanasoula, Stefano Maffini, Claudia Breit, Franziska Müller, Suzan van Gerwen, Tanja Bange, Andrea Musacchio
Published in: Nature, Issue 542/7642, 2017, Page(s) 498-502, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature21384

The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling

Author(s): Veronica Krenn, Andrea Musacchio
Published in: Frontiers in Oncology, Issue 5, 2015, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2015.00225

Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

Author(s): Arsen Petrovic, Jenny Keller, Yahui Liu, Katharina Overlack, Juliane John, Yoana N. Dimitrova, Simon Jenni, Suzan van Gerwen, Patricia Stege, Sabine Wohlgemuth, Pascaline Rombaut, Franz Herzog, Stephen C. Harrison, Ingrid R. Vetter, Andrea Musacchio
Published in: Cell, Issue 167/4, 2016, Page(s) 1028-1040.e15, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2016.10.005

Progress in the structural and functional characterization of kinetochores

Author(s): Marion E Pesenti, John R Weir, Andrea Musacchio
Published in: Current Opinion in Structural Biology, Issue 37, 2016, Page(s) 152-163, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2016.03.003

A Molecular View of Kinetochore Assembly and Function

Author(s): Andrea Musacchio, Arshad Desai
Published in: Biology, Issue 6/4, 2017, Page(s) 5, ISSN 2079-7737
Publisher: Biology
DOI: 10.3390/biology6010005

Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster

Author(s): Yahui Liu, Arsen Petrovic, Pascaline Rombaut, Shyamal Mosalaganti, Jenny Keller, Stefan Raunser, Franz Herzog, Andrea Musacchio
Published in: Open Biology, Issue 6/2, 2016, Page(s) 150236, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.150236

Molecular basis of outer kinetochore assembly on CENP-T

Author(s): Pim J Huis in 't Veld, Sadasivam Jeganathan, Arsen Petrovic, Priyanka Singh, Juliane John, Veronica Krenn, Florian Weissmann, Tanja Bange, Andrea Musacchio
Published in: eLife, Issue 5, 2016, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.21007

Decoding the centromeric nucleosome through CENP-N

Author(s): Satyakrishna Pentakota, Keda Zhou, Charlotte Smith, Stefano Maffini, Arsen Petrovic, Garry P Morgan, John R Weir, Ingrid R Vetter, Andrea Musacchio, Karolin Luger
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.33442

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

Author(s): Marion E. Pesenti, Daniel Prumbaum, Philip Auckland, Charlotte M. Smith, Alex C. Faesen, Arsen Petrovic, Muriel Erent, Stefano Maffini, Satyakrishna Pentakota, John R. Weir, Yu-Chih Lin, Stefan Raunser, Andrew D. McAinsh, Andrea Musacchio
Published in: Molecular Cell, Issue 71/6, 2018, Page(s) 923-939.e10, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.07.038

Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces

Author(s): Vladimir A Volkov, Pim J Huis in 't Veld, Marileen Dogterom, Andrea Musacchio
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.36764

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases

Author(s): Giuseppe Ciossani, Katharina Overlack, Arsen Petrovic, Pim J. Huis in 't Veld, Carolin Koerner, Sabine Wohlgemuth, Stefano Maffini, Andrea Musacchio
Published in: Journal of Biological Chemistry, Issue 293/26, 2018, Page(s) 10084-10101, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.RA118.003154

BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling

Author(s): Katharina Overlack, Tanja Bange, Florian Weissmann, Alex C. Faesen, Stefano Maffini, Ivana Primorac, Franziska Müller, Jan-Michael Peters, Andrea Musacchio
Published in: Current Biology, Issue 27/19, 2017, Page(s) 2915-2927.e7, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2017.08.033