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Vascular Engineering on chip using differentiated Stem Cells

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Publications

Modular operation of microfluidic chips for highly parallelized cell culture and liquid dosing via a fluidic circuit board

Author(s): A. R. Vollertsen, D. de Boer, S. Dekker, B. A. M. Wesselink, R. Haverkate, H. S. Rho, R. J. Boom, M. Skolimowski, M. Blom, R. Passier, A. van den Berg, A. D. van der Meer, M. Odijk
Published in: Microsystems & Nanoengineering, 6/1, 2020, ISSN 2055-7434
Publisher: Springer Nature
DOI: 10.1038/s41378-020-00216-z

Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy

Author(s): Marinke W. van der Helm, Olivier Y. F. Henry, Amir Bein, Tiama Hamkins-Indik, Michael J. Cronce, William D. Leineweber, Mathieu Odijk, Andries D. van der Meer, Jan C. T. Eijkel, Donald E. Ingber, Albert van den Berg, Loes I. Segerink
Published in: Lab on a Chip, 19/3, 2019, Page(s) 452-463, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc00129d

Personalised organs-on-chips: functional testing for precision medicine

Author(s): Albert van den Berg, Christine L. Mummery, Robert Passier, Andries D. van der Meer
Published in: Lab on a Chip, 19/2, 2019, Page(s) 198-205, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc00827b

Automated Analysis of Platelet Aggregation on Cultured Endothelium in a Microfluidic Chip Perfused with Human Whole Blood

Author(s): Albers, Passier, van den Berg, van der Meer
Published in: Micromachines, 10/11, 2019, Page(s) 781, ISSN 2072-666X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi10110781

Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data

Author(s): Pedro F. Costa, Hugo J. Albers, John E. A. Linssen, Heleen H. T. Middelkamp, Linda van der Hout, Robert Passier, Albert van den Berg, Jos Malda, Andries D. van der Meer
Published in: Lab on a Chip, 17/16, 2017, Page(s) 2785-2792, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7lc00202e

Direct quantification of transendothelial electrical resistance in organs-on-chips

Author(s): Marinke W. van der Helm, Mathieu Odijk, Jean-Philippe Frimat, Andries D. van der Meer, Jan C.T. Eijkel, Albert van den Berg, Loes I. Segerink
Published in: Biosensors and Bioelectronics, 85, 2016, Page(s) 924-929, ISSN 0956-5663
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2016.06.014

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Author(s): Marinke W. van der Helm, Mathieu Odijk, Jean-Philippe Frimat, Andries D. van der Meer, Jan C.T. Eijkel, Albert van den Berg, Loes I. Segerink
Published in: Journal of Visualized Experiments, 127, 2017, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/56334

Ruthenium Oxide Nanorods as Potentiometric pH Sensor for Organs-On-Chip Purposes

Author(s): Esther Tanumihardja, Wouter Olthuis, Albert van den Berg
Published in: Sensors, 18/9, 2018, Page(s) 2901, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s18092901

Microfluidic Gel Patterning Method by Use of a Temporary Membrane for Organ-On-Chip Applications

Author(s): Martijn P. Tibbe, Anne M. Leferink, Albert van den Berg, Jan C. T. Eijkel, Loes I. Segerink
Published in: Advanced Materials Technologies, 3/3, 2018, Page(s) 1700200, ISSN 2365-709X
Publisher: WILEY-VCH Verlag GmbH & Co.
DOI: 10.1002/admt.201700200

Flow focusing through gels as a tool to generate 3D concentration profiles in hydrogel-filled microfluidic chips

Author(s): Joshua Loessberg-Zahl, Andries D. van der Meer, Albert van den Berg, Jan C. T. Eijkel
Published in: Lab on a Chip, 19/2, 2019, Page(s) 206-213, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc01140k

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Author(s): Amy Cochrane, Hugo J. Albers, Robert Passier, Christine L. Mummery, Albert van den Berg, Valeria V. Orlova, Andries D. van der Meer
Published in: Advanced Drug Delivery Reviews, 2018, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2018.06.007

Large-scale fabrication of free-standing and sub-μm PDMS through-hole membranes

Author(s): Hai Le-The, Martijn Tibbe, Joshua Loessberg-Zahl, Marciano Palma do Carmo, Marinke van der Helm, Johan Bomer, Albert van den Berg, Anne Leferink, Loes Segerink, Jan Eijkel
Published in: Nanoscale, 10, 2018, Page(s) 7711, ISSN 2040-3372
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7nr09658e

Application of Transmural Flow Across In Vitro Microvasculature Enables Direct Sampling of Interstitial Therapeutic Molecule Distribution

Author(s): Giovanni S. Offeddu, Luca Possenti, Joshua T. Loessberg‐Zahl, Paolo Zunino, John Roberts, Xiaogang Han, Dean Hickman, Charles G. Knutson, Roger D. Kamm
Published in: Small, 15/46, 2019, Page(s) 1902393, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201902393

Improving Organ on‐Chip Physiology: Exploring the barrier in blood‐brain barrier on‐chip systems

Author(s): Martijn Tibbe
Published in: 2020
Publisher: University of Twente
DOI: 10.3990/1.9789036549301

Electrical and microfluidic technologies for organs-on-chips : mimicking blood-brain barrier and gut issues

Author(s): M.W. Helm, van der
Published in: 2018
Publisher: University of Twente
DOI: 10.3990/1.9789036544672

Developing Microfluidic Tooling for 3D Cell-Culture

Author(s): J. Loessberg-Zahl
Published in: 2019
Publisher: University of Twente
DOI: 10.3990/1.9789036549202

Membranes for Organs-on-Chips

Author(s): Tibbe M, Van der Meer A, Van den Berg A, Stamatialis D, Segerink L
Published in: Biomedical Membranes and (Bio) Artificial Organs, 2017, ISBN 978-981-3223-97-4
Publisher: WSPC