Skip to main content

N-Myc and Aurora A: From Protein Stability to Chromosome Topology N-Myc and Aurora A: From Protein Stability to Chromosome Topology Myc and Aurora A: From Protein Stability to Chromosome Topology

Searching for OpenAIRE data...

Publications

Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors

Author(s): Mark W. Richards, Selena G. Burgess, Evon Poon, Anne Carstensen, Martin Eilers, Louis Chesler, Richard Bayliss
Published in: Proceedings of the National Academy of Sciences, Issue 113/48, 2016, Page(s) 13726-13731, ISSN 0027-8424
DOI: 10.1073/pnas.1610626113

Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

Author(s): Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, Olga Sumara, Julia Hofstetter, Steffi Herold, Jacqueline Kalb, Apoorva Baluapuri, Evon Poon, Colin Kwok, Louis Chesler, Hans Michael Maric, David S. Rickman, Elmar Wolf, Richard Bayliss, Susanne Walz, Martin Eilers
Published in: Cell Reports, Issue 21/12, 2017, Page(s) 3483-3497, ISSN 2211-1247
DOI: 10.1016/j.celrep.2017.11.090

Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

Author(s): Giacomo Cossa, Isabelle Roeschert, Florian Prinz, Apoorva Baluapuri, Raphael Silveira Vidal, Christina Schülein-Völk, Yun-Chien Chang, Carsten Patrick Ade, Guido Mastrobuoni, Cyrille Girard, Lars Wortmann, Susanne Walz, Reinhard Lührmann, Stefan Kempa, Bernhard Kuster, Elmar Wolf, Dominik Mumberg, Martin Eilers
Published in: Molecular Cell, 2020, ISSN 1097-2765
DOI: 10.1016/j.molcel.2020.01.008

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

Author(s): Apoorva Baluapuri, Julia Hofstetter, Nevenka Dudvarski Stankovic, Theresa Endres, Pranjali Bhandare, Seychelle Monique Vos, Bikash Adhikari, Jessica Denise Schwarz, Ashwin Narain, Markus Vogt, Shuang-Yan Wang, Robert Düster, Lisa Anna Jung, Jens Thorsten Vanselow, Armin Wiegering, Matthias Geyer, Hans Michael Maric, Peter Gallant, Susanne Walz, Andreas Schlosser, Patrick Cramer, Martin Eilers, El
Published in: Molecular Cell, Issue 74/4, 2019, Page(s) 674-687.e11, ISSN 1097-2765
DOI: 10.1016/j.molcel.2019.02.031

A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

Author(s): Stefanie Schmidt, David Gay, Friedrich Wilhelm Uthe, Sarah Denk, Madelon Paauwe, Niels Matthes, Markus Elmar Diefenbacher, Sheila Bryson, Fiona Clare Warrander, Florian Erhard, Carsten Patrick Ade, Apoorva Baluapuri, Susanne Walz, Rene Jackstadt, Catriona Ford, Georgios Vlachogiannis, Nicola Valeri, Christoph Otto, Christina Schülein-Völk, Katja Maurus, Werner Schmitz, John Raymond Philip Knight
Published in: Nature Cell Biology, Issue 21/11, 2019, Page(s) 1413-1424, ISSN 1465-7392
DOI: 10.1038/s41556-019-0408-0

Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase

Author(s): Steffi Herold, Jacqueline Kalb, Gabriele Büchel, Carsten P. Ade, Apoorva Baluapuri, Jiajia Xu, Jan Koster, Daniel Solvie, Anne Carstensen, Christina Klotz, Sabrina Rodewald, Christina Schülein-Völk, Matthias Dobbelstein, Elmar Wolf, Jan Molenaar, Rogier Versteeg, Susanne Walz, Martin Eilers
Published in: Nature, Issue 567/7749, 2019, Page(s) 545-549, ISSN 0028-0836
DOI: 10.1038/s41586-019-1030-9

Target gene-independent functions of MYC oncoproteins

Author(s): Apoorva Baluapuri, Elmar Wolf, Martin Eilers
Published in: Nature Reviews Molecular Cell Biology, 2020, ISSN 1471-0072
DOI: 10.1038/s41580-020-0215-2