Publications Non-peer reviewed articles (2) Splicing Calls Back Author(s): Tobias Hoffmann, Juan Valcárcel Published in: Cell, Issue 179/7, 2019, Page(s) 1446-1447, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2019.11.028 Empowering MYC carcinogenesis via RNA loops Author(s): Suzanne G. Mays, Juan Valcárcel Published in: Molecular Cell, Issue 81/7, 2021, Page(s) 1365-1367, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2021.03.011 Peer reviewed articles (20) Mutations primarily alter the inclusion of alternatively spliced exons Author(s): Pablo Baeza-Centurion, Belén Miñana, Juan Valcárcel, Ben Lehner Published in: eLife, Issue 9, 2020, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.59959 RNA-binding proteins in human genetic disease Author(s): Fátima Gebauer, Thomas Schwarzl, Juan Valcárcel, Matthias W. Hentze Published in: Nature Reviews Genetics, Issue 22/3, 2021, Page(s) 185-198, ISSN 1471-0056 Publisher: Nature Publishing Group DOI: 10.1038/s41576-020-00302-y Alternative splicing regulation of cell cycle genes by SPF45/SR140/CHERP complex controls cell proliferation Author(s): Elena Martin, Claudia Vivori, Malgorzata Rogalska, Jorge Herrero, Juan Valcarcel Published in: RNA, 2021, Page(s) rna.078935.121, ISSN 1355-8382 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1261/rna.078935.121 Roles and mechanisms of alternative splicing in cancer — implications for care Author(s): Sophie C. Bonnal, Irene López-Oreja, Juan Valcárcel Published in: Nature Reviews Clinical Oncology, Issue 17/8, 2020, Page(s) 457-474, ISSN 1759-4774 Publisher: Nature Publishing Group DOI: 10.1038/s41571-020-0350-x The Spliceosome: The Ultimate RNA Chaperone and Sculptor Author(s): Panagiotis Papasaikas, Juan Valcárcel Published in: Trends in Biochemical Sciences, Issue 41/1, 2016, Page(s) 33-45, ISSN 0968-0004 Publisher: Elsevier BV DOI: 10.1016/j.tibs.2015.11.003 The complete local genotype–phenotype landscape for the alternative splicing of a human exon Author(s): Philippe Julien, Belén Miñana, Pablo Baeza-Centurion, Juan Valcárcel, Ben Lehner Published in: Nature Communications, Issue 7/1, 2016, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/ncomms11558 Structural basis for the recognition of spliceosomal SmN/B/B’ proteins by the RBM5 OCRE domain in splicing regulation Author(s): André Mourão, Sophie Bonnal, Komal Soni, Lisa Warner, Rémy Bordonné, Juan Valcárcel, Michael Sattler Published in: eLife, Issue 5, 2016, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.14707 Tumor suppressor properties of the splicing regulatory factor RBM10 Author(s): Jordi Hernández, Elias Bechara, Doerte Schlesinger, Javier Delgado, Luis Serrano, Juan Valcárcel Published in: RNA Biology, Issue 13/4, 2015, Page(s) 466-472, ISSN 1547-6286 Publisher: Landes Bioscience DOI: 10.1080/15476286.2016.1144004 A synthetic anti-tumor splicing inhibitor variant with improved activity and versatile chemistry Author(s): Makowski, K., Vigevani, L., Albericio, F., Valcárcel, J.* and Álvarez, M*: Sudemycin K * Co-corresponding authors Published in: ACS Chemical Biology, Issue 12/1, 2016, Page(s) 163-173, ISSN 1554-8929 Publisher: American Chemical Society Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 Author(s): Metehan Cifdaloz, Lisa Osterloh, Osvaldo Graña, Erica Riveiro-Falkenbach, Pilar Ximénez-Embún, Javier Muñoz, Cristina Tejedo, Tonantzin G. Calvo, Panagiotis Karras, David Olmeda, Belén Miñana, Gonzalo Gómez-López, Estela Cañon, Eduardo Eyras, Haihong Guo, Ferdinand Kappes, Pablo L. Ortiz-Romero, Jose L. Rodríguez-Peralto, Diego Megías, Juan Valcárcel, María S. Soengas Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-017-02353-y Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice Author(s): Keiko Horiuchi, Serafín Perez-Cerezales, Panagiotis Papasaikas, Priscila Ramos-Ibeas, Angela Patricia López-Cardona, Ricardo Laguna-Barraza, Noelia Fonseca Balvís, Eva Pericuesta, Raul Fernández-González, Benjamín Planells, Alberto Viera, Jose Angel Suja, Pablo Juan Ross, Francisco Alén, Laura Orio, Fernando Rodriguez de Fonseca, Belén Pintado, Juan Valcárcel, Alfonso Gutiérrez-Adán Published in: Cell Reports, Issue 23/1, 2018, Page(s) 143-155, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2018.03.028 Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP Author(s): Luisa Vigevani, André Gohr, Thomas Webb, Manuel Irimia, Juan Valcárcel Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-017-02007-z Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks Author(s): Endre Sebestyén, Babita Singh, Belén Miñana, Amadís Pagès, Francesca Mateo, Miguel Angel Pujana, Juan Valcárcel, Eduardo Eyras Published in: Genome Research, Issue 26/6, 2016, Page(s) 732-744, ISSN 1088-9051 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.199935.115 Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry Author(s): Kamil Makowski, Luisa Vigevani, Fernando Albericio, Juan Valcárcel, Mercedes Álvarez Published in: ACS Chemical Biology, Issue 12/1, 2016, Page(s) 163-173, ISSN 1554-8929 Publisher: American Chemical Society DOI: 10.1021/acschembio.6b00562 Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns Author(s): Sandra Keiper, Panagiotis Papasaikas, Cindy L. Will, Juan Valcárcel, Cyrille Girard, Reinhard Lührmann Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-019-11293-8 Site-Specific mRNA Cleavage for Selective and Quantitative Profiling of Alternative Splicing with Label-Free Optical Biosensors Author(s): Cesar S. Huertas, Sophie Bonnal, Maria Soler, Alfonso M. Escuela, Juan Valcárcel, Laura M. Lechuga Published in: Analytical Chemistry, Issue 91/23, 2019, Page(s) 15138-15146, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.9b03898 Combinatorial Genetics Reveals a Scaling Law for the Effects of Mutations on Splicing Author(s): Pablo Baeza-Centurion, Belén Miñana, Jörn M. Schmiedel, Juan Valcárcel, Ben Lehner Published in: Cell, Issue 176/3, 2019, Page(s) 549-563.e23, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2018.12.010 Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1 Author(s): Claudia Vivori, Panagiotis Papasaikas, Ralph Stadhouders, Bruno Di Stefano, Anna Ribó Rubio, Clara Berenguer Balaguer, Serena Generoso, Anna Mallol, José Luis Sardina, Bernhard Payer, Thomas Graf, Juan Valcárcel Published in: Genome Biology, Issue 22/1, 2021, Page(s) 171, ISSN 1474-760X Publisher: Springer Nature DOI: 10.1186/s13059-021-02372-5 A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons Author(s): Antonio Torres-Méndez, Sophie Bonnal, Yamile Marquez, Jonathan Roth, Marta Iglesias, Jon Permanyer, Isabel Almudí, Dave O’Hanlon, Tanit Guitart, Matthias Soller, Anne-Claude Gingras, Fátima Gebauer, Fabian Rentzsch, Benjamin J. Blencowe, Juan Valcárcel, Manuel Irimia Published in: Nature Ecology & Evolution, Issue 3/4, 2019, Page(s) 691-701, ISSN 2397-334X Publisher: Nature Publishers DOI: 10.1038/s41559-019-0813-6 Functional Network Analysis Reveals the Relevance of SKIIP in the Regulation of Alternative Splicing by p38 SAPK Author(s): Caterina Carbonell, Arnau Ulsamer, Claudia Vivori, Panagiotis Papasaikas, René Böttcher, Manel Joaquin, Belén Miñana, Juan Ramón Tejedor, Eulàlia de Nadal, Juan Valcárcel, Francesc Posas Published in: Cell Reports, Issue 27/3, 2019, Page(s) 847-859.e6, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2019.03.060 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
