Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment

Project Information

AVATAR

Grant agreement ID: 670582

DOI 10.3030/670582

Project terminated on 31 January 2020

EC signature date 25 September 2015

Start date 1 October 2015

End date 30 September 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 498 687,50

EU contribution € 2 498 687,50

Coordinated by

HOSPITAL UNIVERSITARIO DE FUENLABRADA
Spain

Publications

Conference proceedings (1)

Abstract CT119: Organoid sensitivity in pancreatic cancer correlates with clinical response to treatment and reveals utility for reducing toxicity: Preliminary results from the HOPE trial

Author(s): Joseph Elan Grossman, Ling Huang, Lakshmi Muthuswamy, Sofia Perea, Dipikaa Akshinthala, Raul Gonzalez, Leo Tsai, Jonah Cohen, Mandeep Sawhney, Douglas Pleskow, Tyler M. Berzin, Bruno Bockorny, Andrea Bullock, Benjamin Schlechter, Mary Linton B. Peters, Catherine Conahan, Supraja Narasimhan, Christine Lim, Roger Davis, Robert Besaw, Martin Smith, Tara Kent, Mark Callery, Senthil K. Muthuswamy, Manu
Published in: Tumor Biology, 2020, Page(s) CT119-CT119
Publisher: American Association for Cancer Research
DOI: 10.1158/1538-7445.am2020-ct119

Peer reviewed articles (2)

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

Author(s): María Teresa Blasco, Carolina Navas, Guillermo Martín-Serrano, Osvaldo Graña-Castro, Carmen G. Lechuga, Laura Martín-Díaz, Magdolna Djurec, Jing Li, Lucia Morales-Cacho, Laura Esteban-Burgos, Javier Perales-Patón, Emilie Bousquet-Mur, Eva Castellano, Harrys K.C. Jacob, Lavinia Cabras, Monica Musteanu, Matthias Drosten, Sagrario Ortega, Francisca Mulero, Bruno Sainz, Nelson Dusetti, Juan Iova
Published in: Cancer Cell, Issue 35/4, 2019, Page(s) 573-587.e6, ISSN 1535-6108
Publisher: Cell Press
DOI: 10.1016/j.ccell.2019.03.002

Interrogating open issues in cancer precision medicine with patient-derived xenografts

Author(s): Annette T. Byrne, Denis G. Alférez, Frédéric Amant, Daniela Annibali, Joaquín Arribas, Andrew V. Biankin, Alejandra Bruna, Eva Budinská, Carlos Caldas, David K. Chang, Robert B. Clarke, Hans Clevers, George Coukos, Virginie Dangles-Marie, S. Gail Eckhardt, Eva Gonzalez-Suarez, Els Hermans, Manuel Hidalgo, Monika A. Jarzabek, Steven de Jong, Jos Jonkers, Kristel Kemper, Luisa Lanfrancone, Gunh
Published in: Nature Reviews Cancer, Issue 17/4, 2017, Page(s) 254-268, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.1038/nrc.2016.140