Immunological synapse derived ectosomes in T cell effector function

Project Information

SYNECT

Grant agreement ID: 670930

DOI

10.3030/670930

Project closed

EC signature date 30 September 2015

Start date 1 November 2015

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 212 114,00

EU contribution

€ 2 212 114,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

Author(s): Thomas Riffelmacher, Alexander Clarke, Felix C. Richter, Amanda Stranks, Sumeet Pandey, Sara Danielli, Philip Hublitz, Zhanru Yu, Errin Johnson, Tobias Schwerd, James McCullagh, Holm Uhlig, Sten Eirik W. Jacobsen, Anna Katharina Simon
Published in: Immunity, Issue 47/3, 2017, Page(s) 466-480.e5, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2017.08.005

TFH-derived dopamine accelerates productive synapses in germinal centres

Author(s): Ilenia Papa, David Saliba, Maurilio Ponzoni, Sonia Bustamante, Pablo F. Canete, Paula Gonzalez-Figueroa, Hayley A. McNamara, Salvatore Valvo, Michele Grimbaldeston, Rebecca A. Sweet, Harpreet Vohra, Ian A. Cockburn, Michael Meyer-Hermann, Michael L. Dustin, Claudio Doglioni, Carola G. Vinuesa
Published in: Nature, Issue 547/7663, 2017, Page(s) 318-323, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature23013

Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse

Author(s): Viveka Mayya, Edward Judokusumo, Enas Abu Shah, Christopher G. Peel, Willie Neiswanger, David Depoil, David A. Blair, Chris H. Wiggins, Lance C. Kam, Michael L. Dustin
Published in: Cell Reports, Issue 22/2, 2018, Page(s) 340-349, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.12.052

Maintenance of CD4 T cell fitness through regulation of Foxo1

Author(s): Ryan H. Newton, Sharad Shrestha, Jenna M. Sullivan, Kathleen B. Yates, Ewoud B. Compeer, Noga Ron-Harel, Bruce R. Blazar, Steven J. Bensinger, W. Nicholas Haining, Michael L. Dustin, Daniel J. Campbell, Hongbo Chi, Laurence A. Turka
Published in: Nature Immunology, Issue 19/8, 2018, Page(s) 838-848, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-018-0157-4

What Scales the T Cell Response?

Author(s): Viveka Mayya, Michael L. Dustin
Published in: Trends in Immunology, Issue 37/8, 2016, Page(s) 513-522, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2016.06.005

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

Author(s): David G Saliba, Pablo F Céspedes-Donoso, Štefan Bálint, Ewoud B Compeer, Kseniya Korobchevskaya, Salvatore Valvo, Viveka Mayya, Audun Kvalvaag, Yanchun Peng, Tao Dong, Maria-Laura Tognoli, Eric O'Neill, Sarah Bonham, Roman Fischer, Benedikt M Kessler, Michael L Dustin
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.47528

Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion

Author(s): Charles A. Coomer, Irene Carlon-Andres, Maro Iliopoulou, Michael L. Dustin, Ewoud B. Compeer, Alex A. Compton, Sergi Padilla-Parra
Published in: PLOS Pathogens, Issue 16/2, 2020, Page(s) e1008359, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1008359

Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts

Author(s): Viveka Mayya, Edward Judokusumo, Enas Abu-Shah, Willie Neiswanger, Chirag Sachar, David Depoil, Lance C. Kam, Michael L. Dustin
Published in: The Journal of Immunology, Issue 203/3, 2019, Page(s) 601-606, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1801687

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

Author(s): Š. Bálint, S. Müller, R. Fischer, B. M. Kessler, M. Harkiolaki, S. Valitutti, M. L. Dustin
Published in: Science, Issue 368/6493, 2020, Page(s) 897-901, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aay9207

A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

Author(s): Enas Abu-Shah, Philippos Demetriou, Štefan Bálint, Viveka Mayya, Mikhail A Kutuzov, Omer Dushek, Michael L Dustin
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.48221

Non-peer reviewed articles (1)

ISEV2018 abstract book

Author(s): Stefan Balint Michael Dustin
Published in: Journal of Extracellular Vesicles, Issue 7/sup1, 2018, Page(s) 1461450, ISSN 2001-3078
Publisher: International Society of Extracellular Vesicles
DOI: 10.1080/20013078.2018.1461450