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Upscaling Synthesis of Ordered mesoporous silica material for Drug delivery Applications

Objective

FORMAC Pharmaceuticals NV is actively developing and commercialising an innovative and proprietary drug delivery technology to increase the oral bioavailability of poorly aqueous soluble drugs. Those molecules represent up to seventy percent of the compounds in discovery pipelines and up to forty percent of the currently marketed drugs. Based on the use of Ordered Mesoporous Silica (OMS) materials, FORMAC’s platform enables clients’ molecules to be formulated as oral drug products for early development, life cycle management or generic development. FORMAC is key leader in this emerging field with more than twenty different collaboration agreements and fifty molecules tested. Together with its validation in a human clinical setting, numerous regulatory consultations on EU level have been conducted. FORMAC is now ready to secure its first licensing deal with a pharmaceutical or generic company. However, some remaining challenges are hampering full deployment of FORMAC’s technology platform. Given its development stage, the company is still facing (i) an unfavourable cost of goods profile linked to the current OMS synthesis process and (ii) its limited manufacturing scale. The current proposal will unlock the first limitation and create possibilities for further upscaling. FORMAC’s ultimate goal is to bring OMS based drug delivery to the global market.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

FORMAC PHARMACEUTICALS NV
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
GASTON GEENSLAAN 2
3001 LEUVEN
Belgium

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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