Objective
Interdisciplinary science and technologies have converged in the last few years to create exciting challenges and opportunities involving novel, integrated separation systems to facilitate comprehensive analysis of complex biological samples. Bioseparation science is an essential toolset that enables entering from the genomics era to the proteomics field. The aim of the proposed research and training project is to develop and implement high performance bioanalytical techniques for the field of proteomics based biomarker discovery using single- and multi-dimensional separation methods. One of the main focuses is the establishment of novel column technologies for differential migration processes in micro-channel based bioanalytical systems, such as capillary electrophoresis, capillary electrochromatography and microfabricated separation devices, respectively connected to mass spectrometry. Identification of quantitative and/or qualitative protein expression differences as well as characterisation of various cell proteomes will significantly advance biomedical research and diagnostics. Our novel, high performance bioseparation approaches will be applied to reveal global changes in gene expression at the proteome level. Analysis throughput will be increased by multiplexing and system integration provided by contemporary microfabrication approaches. Up and down-regulation, as well as appearance and disappearance of specific proteins or groups of proteins encountered in cellular systems subjected to changes in such physiological conditions as cancer will be individually screened and identified in order to find surrogate biological markers to be used in early disease diagnostics and speed up clinical trials. This Marie Curie Chair award would practically support the establishment of a new bioseparation science research and training centre in the Central European region for outstanding young researchers from the European Community including the newly joined EU countries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- social sciences economics and business business and management business models
- natural sciences chemical sciences electrochemistry electrophoresis
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-10
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
INNSBRUCK
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.