Resultado final Documents, reports (12) property model library and database Validated thermodynamic models library and database for charged molecules. Healthcare products formulated Predictive bioavailability model for production of structured emulsified products for healthcare applications. Control bioprocess Application of the framework for a ‘closed-loop’ bioprocess control application. Oleochemicals process designed Techno-economic and sustainability assessment of optimal process (flowsheet) design for oleochemicals derived products including design of control strategies for recovery of value added products. Sustainable process design Improved LCA tool and its implementation as a software prototype for sustainability analysis and process design using comprehensive uncertainty analysis for selected applications Integrated MD & phase equilibrium models An integrated molecular dynamics and phase equilibrium modeling for complex formulated products. In situ measurement A report on different analytical techniques for in situ measurement of the processes in WP5. Multi-scale models Upstream and downstream multi-scale models of culture cells. multicentre PhD training Framework & curricula for multicentre PhD training programme in engineering for life sciences and biotechnology industries. PG certificate Postgraduate Certificates in Researcher Professional Development (PG Cert RDP) will be awarded by USTRATH to at least 8 ESRs recruited by ModLife network. Methodology Methodology for data reduction Data fusion Methodologies for spectroscopic and process data fusion and software implementation of data fusion algorithms. Publicaciones Peer reviewed articles (24) Dynamic plantwide modeling, uncertainty and sensitivity analysis of a pharmaceutical upstream synthesis: Ibuprofen case study Autores: Frederico Montes, Krist V. Gernaey, Gurkan Sin Publicado en: Industrial & Engineering Chemistry Research, 2018, ISSN 0888-5885 Editor: American Chemical Society DOI: 10.1021/acs.iecr.8b00465 Near-infrared hyperspectral imaging for non-destructive classification of commercial tea products Autores: Puneet Mishra, Alison Nordon, Julius Tschannerl, Guoping Lian, Sally Redfern, Stephen Marshall Publicado en: Journal of Food Engineering, 2018, ISSN 0260-8774 Editor: Elsevier BV DOI: 10.1016/j.jfoodeng.2018.06.015 The Increasingly Human and Profitable Monoclonal Antibody Market Autores: António L. Grilo, A. Mantalaris Publicado en: Trends in Biotechnology, 2018, ISSN 0167-7799 Editor: Elsevier BV DOI: 10.1016/j.tibtech.2018.05.014 Fusing spectral and textural information in near-infrared hyperspectral imaging to improve green tea classification modelling Autores: Puneet Mishra, Alison Nordon, Mohd Shahrimie Mohd Asaari, Guoping Lian, Sally Redfern Publicado en: Journal of Food Engineering, Issue 249, 2019, Page(s) 40-47, ISSN 0260-8774 Editor: Elsevier BV DOI: 10.1016/J.JFOODENG.2019.01.009 GPdoemd: A Python package for design of experiments for model discrimination Autores: Simon Olofsson, Lukas Hebing, Sebastian Niedenführ, Marc Peter Deisenroth, Ruth Misener Publicado en: Computers & Chemical Engineering, Issue 125, 2019, Page(s) 54-70, ISSN 0098-1354 Editor: Pergamon Press Ltd. DOI: 10.1016/j.compchemeng.2019.03.010 Model-Based Dynamic Optimization of Monoclonal Antibodies Production in Semibatch Operation—Use of Reformulation Techniques Autores: Chrysoula D. Kappatou, Adel Mhamdi, Ana Quiroga Campano, Athanasios Mantalaris, Alexander Mitsos Publicado en: Industrial & Engineering Chemistry Research, Issue 57/30, 2018, Page(s) 9915-9924, ISSN 0888-5885 Editor: American Chemical Society DOI: 10.1021/acs.iecr.7b05357 Maximizing neotissue growth kinetics in a perfusion bioreactor: An in silico strategy using model reduction and Bayesian optimization Autores: Mohammad Mehrian, Yann Guyot, Ioannis Papantoniou, Simon Olofsson, Maarten Sonnaert, Ruth Misener, Liesbet Geris Publicado en: Biotechnology and Bioengineering, Issue 115/3, 2018, Page(s) 617-629, ISSN 0006-3592 Editor: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/bit.26500 Modeling of double emulsions using population balance equations Autores: Behnam Khadem, Nida Sheibat-Othman Publicado en: Chemical Engineering Journal, Issue 366, 2019, Page(s) 587-597, ISSN 1385-8947 Editor: Elsevier BV DOI: 10.1016/j.cej.2019.02.092 The Monte Carlo driven and machine learning enhanced process simulator Autores: Mark Nicholas Jones, Jérôme Frutiger, Nevin Gerek Ince, Gürkan Sin Publicado en: Computers & Chemical Engineering, Issue 125, 2019, Page(s) 324-338, ISSN 0098-1354 Editor: Pergamon Press Ltd. DOI: 10.1016/j.compchemeng.2019.03.016 Meta-modeling based efficient global sensitivity analysis for wastewater treatment plants – An application to the BSM2 model Autores: Resul Al, Chitta Ranjan Behera, Alexandr Zubov, Krist V. Gernaey, Gürkan Sin Publicado en: Computers & Chemical Engineering, Issue 127, 2019, Page(s) 233-246, ISSN 0098-1354 Editor: Pergamon Press Ltd. DOI: 10.1016/j.compchemeng.2019.05.015 Apoptosis: A mammalian cell bioprocessing perspective Autores: Antonio L. Grilo, Athanasios Mantalaris Publicado en: Biotechnology Advances, Issue 37/3, 2019, Page(s) 459-475, ISSN 0734-9750 Editor: Elsevier BV DOI: 10.1016/j.biotechadv.2019.02.012 Automatic de-noising of close-range hyperspectral images with a wavelength-specific shearlet-based image noise reduction method Autores: Puneet Mishra, Azam Karami, Alison Nordon, Douglas N. Rutledge, Jean-Michel Roger Publicado en: Sensors and Actuators B: Chemical, Issue 281, 2019, Page(s) 1034-1044, ISSN 0925-4005 Editor: Elsevier BV DOI: 10.1016/j.snb.2018.11.034 An evaluation of in-silico methods for predicting solute partition in multiphase complex fluids – A case study of octanol/water partition coefficient Autores: Mattia Turchi, Qiong Cai, Guoping Lian Publicado en: Chemical Engineering Science, Issue 197, 2019, Page(s) 150-158, ISSN 0009-2509 Editor: Pergamon Press Ltd. DOI: 10.1016/j.ces.2018.12.003 In Silico Prediction of the Thermodynamic Equilibrium of Solute Partition in Multiphase Complex Fluids: A Case Study of Oil–Water Microemulsion Autores: Mattia Turchi, Qiong Cai, Guoping Lian Publicado en: Langmuir, Issue 35/33, 2019, Page(s) 10855-10865, ISSN 0743-7463 Editor: American Chemical Society DOI: 10.1021/acs.langmuir.9b01513 Theoretical and Experimental Investigations of Double Emulsion Preparation by Ultrasonication Autores: Behnam Khadem, Nida Sheibat-Othman Publicado en: Industrial & Engineering Chemistry Research, Issue 58/19, 2019, Page(s) 8220-8230, ISSN 0888-5885 Editor: American Chemical Society DOI: 10.1021/acs.iecr.9b00556 A Predictive Mathematical Model of Cell Cycle, Metabolism, and Apoptosis of Monoclonal Antibody‐Producing GS–NS0 Cells Autores: António L. Grilo, Athanasios Mantalaris Publicado en: Biotechnology Journal, 2019, Page(s) 1800573, ISSN 1860-6768 Editor: Wiley - VCH Verlag GmbH & CO. KGaA DOI: 10.1002/biot.201800573 Investigating swelling-breakdown in double emulsions Autores: Behnam Khadem, Maya Khellaf, Nida Sheibat-Othman Publicado en: Colloids and Surfaces A: Physicochemical and Engineering Aspects, Issue 585, 2020, Page(s) 124181, ISSN 0927-7757 Editor: Elsevier BV DOI: 10.1016/j.colsurfa.2019.124181 Comprehensive development, uncertainty and sensitivity analysis of a model for the hydrolysis of rapeseed oil Autores: Hector Forero-Hernandez, Mark Nicholas Jones, Bent Sarup, Anker Degn Jensen, Jens Abildskov, Gürkan Sin Publicado en: Computers & Chemical Engineering, Issue 133, 2020, Page(s) 106631, ISSN 0098-1354 Editor: Pergamon Press Ltd. DOI: 10.1016/j.compchemeng.2019.106631 Modeling droplets swelling and escape in double emulsions using population balance equations Autores: Behnam Khadem, Nida Sheibat-Othman Publicado en: Chemical Engineering Journal, Issue 382, 2020, Page(s) 122824, ISSN 1385-8947 Editor: Elsevier BV DOI: 10.1016/j.cej.2019.122824 Guaranteed satisfaction of inequality state constraints in PDE-constrained optimization Autores: Eduardo S. Schultz, Ralf Hannemann-Tamás, Alexander Mitsos Publicado en: Automatica, Issue 111, 2020, Page(s) 108653, ISSN 0005-1098 Editor: Pergamon Press Ltd. DOI: 10.1016/j.automatica.2019.108653 Bayesian Multiobjective Optimisation With Mixed Analytical and Black-Box Functions: Application to Tissue Engineering Autores: Simon Olofsson, Mohammad Mehrian, Roberto Calandra, Liesbet Geris, Marc Peter Deisenroth, Ruth Misener Publicado en: IEEE Transactions on Biomedical Engineering, Issue 66/3, 2019, Page(s) 727-739, ISSN 0018-9294 Editor: Institute of Electrical and Electronics Engineers DOI: 10.1109/tbme.2018.2855404 Splitting Triglycerides with a Counter-Current Liquid–Liquid Spray Column: Modeling, Global Sensitivity Analysis, Parameter Estimation and Optimization Autores: Mark Jones, Hector Forero-Hernandez, Alexandr Zubov, Bent Sarup, Gürkan Sin Publicado en: Processes, Issue 7/12, 2019, Page(s) 881, ISSN 2227-9717 Editor: MDPI Processes DOI: 10.3390/pr7120881 Reliable Correlation for Liquid–Liquid Equilibria outside the Critical Region Autores: Łukasz Ruszczyński, Alexandr Zubov, John P. O’Connell, Jens Abildskov Publicado en: Journal of Chemical & Engineering Data, Issue 62/9, 2017, Page(s) 2842-2854, ISSN 0021-9568 Editor: American Chemical Society DOI: 10.1021/acs.jced.7b00164 Reply to “Comment on ‘Reliable Correlation for Liquid–Liquid Equilibria outside the Critical Region’” Autores: Łukasz Ruszczyński, Alexandr Zubov, John P. O’Connell, Jens Abildskov Publicado en: Journal of Chemical & Engineering Data, Issue 62/11, 2017, ISSN 0021-9568 Editor: American Chemical Society DOI: 10.1021/acs.jced.7b00724 Conference proceedings (14) Design of Experiments for Model Discrimination Hybridising Analytical and Data-Driven Approaches Autores: Olofsson, Simon; Deisenroth, Marc Peter; Misener, Ruth Publicado en: Proceedings of the 35th International Conference on Machine Learning, ICML, 2018, ISSN 1938-7228 Editor: PMLR From property uncertainties to process simulation uncertainties – Monte Carlo methods in SimSci PRO/II process simulator Autores: Jérôme Frutiger, Mark Jones, Nevin Gerek Ince, Gürkan Sin Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 1489-1494, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50243-3 Homogenising and segmenting hyperspectral images of plants and testing chemicals in a high-throughput phenotyping setup Autores: Mishra P., Schmuck M., Roth S., Nicol A., Nordon A. Publicado en: 2019 10th Workshop on Hyperspectral Imaging and Signal Processing, 2019 Editor: Whispers 2019- IEEE workshop on hyperspectral images and signal processing: an evolution in remote sensing Early detection of drought stress in Arabidopsis Thaliana utilising a portable hyperspectral imaging setup Autores: Mishra P., Feller T., Schmuck M., Nicol A., Nordon A. Publicado en: 2019 10th Workshop on Hyperspectral Imaging and Signal Processing, 2019 Editor: Whispers 2019- IEEE workshop on hyperspectral images and signal processing: an evolution in remote sensing How to Use Mechanistic Metabolic Modeling to Ensure High Quality Glycoprotein Production Autores: Alireza Ehsani, Sebastian Niedenfuehr, Thomas Eissing, Swantje Behnken, Andreas Schuppert Publicado en: 27th European Symposium on Computer Aided Process Engineering, Issue 40, 2017, Page(s) 2839-2844, ISBN 9780-444639653 Editor: Elsevier DOI: 10.1016/b978-0-444-63965-3.50475-x Data Validation and Modelling of Thermodynamic Properties of Systems with Active Pharmaceutical Ingredients (APIs) in Complex Media for Skin Absorption Processes Autores: Ruszczynski L., Zubov A., Sin G., Abildskov J. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 247-252, ISBN 978-0-444-64080-2 Editor: Elsevier DOI: 10.1016/B978-0-444-63965-3.50043-X Methodology for Plantwide Design and Optimization of Wastewater Treatment Plants Autores: Dragan J.M., Zubov A., Sin G. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 859-864, ISBN 978-0-444-64080-2 Editor: Elsevier Bayesian Multi-Objective Optimisation of Neotissue Growth in a Perfusion Bioreactor Set-Up Autores: Olofsson S., Mehrian M., Geris L., Calandra R., Deisenroth M.P., Misener R. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 2155-2160, ISBN 978-0-444-64079-6 Editor: Elsevier Dynamic Optimization of the Production of Monoclonal Antibodies in Semi-batch Operation Autores: Kappatou C.D., Mhamdi A., Campano A.Q., Mantalaris A., Mitsos A. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 2161-2166, ISBN 978-0-444-64079-6 Editor: Elsevier Modeling Stability of Double Emulsions Autores: Khadem B., Sheibat-Othman N. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 493-498, ISBN 978-0-444-64080-2 Editor: Elsevier DOI: 10.1016/B978-0-444-63965-3.50084-2 Multi-scale Modelling of Solute Partition Equilibria of Micelle-Water and Microemulsion-Water Systems Using Molecular Dynamics and COSMOtherm Autores: Turchi M., Lian G., Cai Q., Wood I., Rabone J., Noro M. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 2773-2778, ISBN 978-0-444-64079-6 Editor: Elsevier DOI: 10.1016/B978-0-444-63965-3.50464-5 A Simplified Kinetic and Mass Transfer Modelling of the Thermal Hydrolysis of Vegetable Oils Autores: Forero-Hernandez H., Jones M., Sarup B., Abildskov J., Jensen A.D., Sin G. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 1177-1182, ISBN 978-0-444-64080-2 Editor: Elsevier DOI: 10.1016/B978-0-444-63965-3.50198-7 Multi-scale Modeling Approach for Design and Optimization of Oleochemical Processes Autores: Mark Jones, Hector Forero-Hernandez, Bent Sarup, Gürkan Sin Publicado en: 27th European Symposium on Computer Aided Process Engineering, Issue 40, 2017, Page(s) 1885-1890, ISBN 9780-444639653 Editor: Elsevier DOI: 10.1016/b978-0-444-63965-3.50316-0 Uncertainty and Sensitivity Analysis for an Ibuprofen Synthesis Model Based on Hoechst Path Autores: Montes F., Gernaey K.V., Sin G. Publicado en: 27th European Symposium on Computer Aided Process Engineering, 2017, Page(s) 163-168, ISBN 978-0-444-64080-2 Editor: Elsevier DOI: 10.1016/B978-0-444-63965-3.50029-5 Book chapters (11) Process Synthesis, Design, and Control of Wastewater Treatment Plants Autores: Xueming Chen, Resul Al, Chitta Ranjan Behera, Gürkan Sin Publicado en: Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2018, ISBN 9780-124095472 Editor: Elsevier DOI: 10.1016/b978-0-12-409547-2.14345-8 Prediction of Environmental Properties Using a Hybrid Group Contribution Approach Autores: Resul Al, Jérôme Frutiger, Alexandr Zubov, Gürkan Sin Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 1723-1728, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50282-2 Design of Experiments for Model Discrimination using Gaussian Process Surrogate Models Autores: Simon Olofsson, Marc Peter Deisenroth, Ruth Misener Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 847-852, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50136-1 A Modular Modelling Environment for Computer-Aided Process Design Autores: Mark Nicholas Jones, Simon Anthony Jones, Gürkan Sin Publicado en: Proceedings of the 9th International Conference on Foundations of Computer-Aided Process Design, Issue 47, 2019, Page(s) 23-28, ISBN 9780-128185971 Editor: Elsevier DOI: 10.1016/b978-0-12-818597-1.50004-7 Superstructure Optimization of Oleochemical Processes with Surrogate Models Autores: Mark Jones, Hector Forero-Hernandez, Alexandr Zubov, Bent Sarup, Gürkan Sin Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 277-282, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50041-0 Systematic framework development for the construction of surrogate models for wastewater treatment plants Autores: Resul Al, Chitta Ranjan Behera, Alexandr Zubov, Gürkan Sin Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 1909-1914, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50313-x Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization Autores: Resul Al, Chitta Ranjan Behera, Krist V. Gernaey, Gürkan Sin Publicado en: 29th European Symposium on Computer Aided Process Engineering, Issue 46, 2019, Page(s) 325-330, ISBN 9780-128186343 Editor: Elsevier DOI: 10.1016/b978-0-12-818634-3.50055-2 Implementation of a Radial Basis Function control strategy for the crystallization of Ibuprofen under uncertainty Autores: Frederico Montes, Krist V. Gernaey, Gürkan Sin Publicado en: 13th International Symposium on Process Systems Engineering (PSE 2018), Issue 44, 2018, Page(s) 565-570, ISBN 9780-444642417 Editor: Elsevier DOI: 10.1016/b978-0-444-64241-7.50089-6 Property Prediction of Pharmaceuticals for Designing of Downstream Separation Processes Autores: Getachew S. Molla, Lukasz Ruszczynski, Jens Abildskov, Gürkan Sin Publicado en: 28th European Symposium on Computer Aided Process Engineering, Issue 43, 2018, Page(s) 287, ISBN 9780-444642356 Editor: Elsevier DOI: 10.1016/b978-0-444-64235-6.50051-6 Sequential and Simultaneous Optimization Strategies for Increased Production of Monoclonal Antibodies Autores: Chrysoula D. Kappatou, Oktay Altunok, Adel Mhamdi, Athanasios Mantalaris, Alexander Mitsos Publicado en: 29th European Symposium on Computer Aided Process Engineering, Issue 46, 2019, Page(s) 1021-1026, ISBN 9780-128186343 Editor: Elsevier DOI: 10.1016/b978-0-12-818634-3.50171-5 Towards Model-Based Optimization for Quality by Design in Biotherapeutics Production Autores: Alireza Ehsani, Chrysoula Dimitra Kappatou, Adel Mhamdi, Alexander Mitsos, Andreas Schuppert, Sebastian Niedenfuehr Publicado en: 29th European Symposium on Computer Aided Process Engineering, Issue 46, 2019, Page(s) 25-30, ISBN 9780-128186343 Editor: Elsevier DOI: 10.1016/b978-0-12-818634-3.50005-9 Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
