Objective
Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases.
The TRAIN-ERS network will provide early stage researchers (ESRs) with high quality scientific and complementary skills training combined with international, intersectoral work experience. This will produce highly trained, innovative, creative and entrepreneurial ESRs with greatly enhanced career prospects, who will continue to advance the state of the art in the Biomedical field in their further careers, and will confidently navigate at the interface of academic, clinical and private sector research. The TRAIN-ERS research programme will provide the ESR’s with the knowledge and the cutting edge scientific and technical skills that will drive our understanding and exploitation of the ER stress response for therapeutic and diagnostic purposes.
Fields of science
- medical and health scienceshealth sciencesinflammatory diseases
- medical and health sciencesclinical medicinecritical care medicine
- medical and health sciencesclinical medicineoncologyskin cancermelanoma
- medical and health sciencesclinical medicineoncologybreast cancer
- medical and health sciencesbasic medicineneurologyamyotrophic lateral sclerosis
Programme(s)
Funding Scheme
MSCA-ITN-ETN - European Training Networks
Coordinator
H91 Galway
Ireland
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Participants (11)
75654 Paris
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60323 Frankfurt Am Main
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F94 TV06 Donegall
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405 30 Goeteborg
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08908 L'hospitalet De Llobregat
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1090 Wien
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Participation ended
2 Dublin
3000 Leuven
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SW7 2AZ London
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Participation ended
6299920 Tel Aviv
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
70174 Stuttgart
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Partners (6)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
91355 Valencia
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
WC1B 5HA London
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
37341 Hluboka Nad Vltavou
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
52062 Aachen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
69120 Heidelberg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
MA 02421 Lexington
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