Chromatin and Metabolism Chromatin-metabolism interactions as targets for healthy living

Project Information

ChroMe

Grant agreement ID: 675610

DOI

10.3030/675610

Project closed

EC signature date 5 April 2016

Start date 1 March 2016

End date 29 February 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 3 825 128,16

EU contribution

€ 3 825 128,16

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Call for abstracts

Online publication of call for abstracts for Frontiers in Genetics (following Communication II)

Article collection

Publication of all Frontiers in Genetics articles (following Communication III)

Websites, patent fillings, videos etc. (1)

Network website

Info for network website provided to Chronos and Facebook page online

Publications

Peer reviewed articles (24)

Mfn2 is critical for brown adipose tissue thermogenic function

Author(s): Marie Boutant, Sameer S Kulkarni, Magali Joffraud, Joanna Ratajczak, Miriam Valera‐Alberni, Roy Combe, Antonio Zorzano, Carles Cantó
Published in: The EMBO Journal, Issue 36/11, 2017, Page(s) 1543-1558, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201694914

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption

Author(s): Melanija Posavec Marjanović, Sarah Hurtado-Bagès, Maximilian Lassi, Vanesa Valero, Roberto Malinverni, Hélène Delage, Miriam Navarro, David Corujo, Iva Guberovic, Julien Douet, Pau Gama-Perez, Pablo M Garcia-Roves, Ivan Ahel, Andreas G Ladurner, Oscar Yanes, Philippe Bouvet, Mònica Suelves, Raffaele Teperino, J Andrew Pospisilik, Marcus Buschbeck
Published in: Nature Structural & Molecular Biology, Issue 24/11, 2017, Page(s) 902-910, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/nsmb.3481

The MacroH2A1.1 – PARP1 Axis at the Intersection Between Stress Response and Metabolism

Author(s): Sarah Hurtado-Bagès, Iva Guberovic, Marcus Buschbeck
Published in: Frontiers in Genetics, Issue 9, 2018, Page(s) 1-10, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00417

Long Non-coding RNAs as Local Regulators of Pancreatic Islet Transcription Factor Genes

Author(s): Berta Font-Cunill, Luis Arnes, Jorge Ferrer, Lori Sussel, Anthony Beucher
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00524

Polyphenism – A Window Into Gene-Environment Interactions and Phenotypic Plasticity

Author(s): Chih-Hsiang Yang, John Andrew Pospisilik
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.00132

Epigenetic Regulation at the Interplay Between Gut Microbiota and Host Metabolism

Author(s): Joan Miro-Blanch, Oscar Yanes
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.00638

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

Author(s): Tess Tsai-Hsiu Lu, Steffen Heyne, Erez Dror, Eduard Casas, Laura Leonhardt, Thorina Boenke, Chih-Hsiang Yang, Sagar, Laura Arrigoni, Kevin Dalgaard, Raffaele Teperino, Lennart Enders, Madhan Selvaraj, Marius Ruf, Sunil J. Raja, Huafeng Xie, Ulrike Boenisch, Stuart H. Orkin, Francis C. Lynn, Brad G. Hoffman, Dominic Grün, Tanya Vavouri, Adelheid M. Lempradl, J. Andrew Pospisilik
Published in: Cell Metabolism, Issue 27/6, 2018, Page(s) 1294-1308.e7, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2018.04.013

The Impact of One Carbon Metabolism on Histone Methylation

Author(s): Magdalini Serefidou, Anuroop Venkateswaran Venkatasubramani, Axel Imhof
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.00764

Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation

Author(s): Christophe O. Soulage, Laura Sardón Puig, Laurent Soulère, Bader Zarrouki, Michel Guichardant, Michel Lagarde, Nicolas J. Pillon
Published in: Diabetologia, Issue 61/3, 2018, Page(s) 688-699, ISSN 0012-186X
Publisher: Springer Verlag
DOI: 10.1007/s00125-017-4528-4

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms

Author(s): Marek Kozlowski, David Corujo, Michael Hothorn, Iva Guberovic, Imke K Mandemaker, Charlotte Blessing, Judith Sporn, Arturo Gutierrez‐Triana, Rebecca Smith, Thomas Portmann, Mathias Treier, Klaus Scheffzek, Sebastien Huet, Gyula Timinszky, Marcus Buschbeck, Andreas G Ladurner
Published in: EMBO reports, Issue 19/10, 2018, Page(s) 1-13, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.201744445

The Role of Mammalian Creb3-Like Transcription Factors in Response to Nutrients

Author(s): Haris A. Khan, Carla E. Margulies
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.00591

Exploiting the Circadian Clock for Improved Cancer Therapy: Perspective From a Cell Biologist

Author(s): Tia Tyrsett Kuo, Andreas G. Ladurner
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.01210

Circadian Rhythms and Mitochondria: Connecting the Dots

Author(s): Laura Sardon Puig, Miriam Valera-Alberni, Carles Cantó, Nicolas J. Pillon
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00452

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

Author(s): Nicolas J. Pillon, Brendan M. Gabriel, Lucile Dollet, Jonathon A. B. Smith, Laura Sardón Puig, Javier Botella, David J. Bishop, Anna Krook, Juleen R. Zierath
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13869-w

Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism

Author(s): Ahmed M. Abdelmoez, Laura Sardón Puig, Jonathon A. B. Smith, Brendan M. Gabriel, Mladen Savikj, Lucile Dollet, Alexander V. Chibalin, Anna Krook, Juleen R. Zierath, Nicolas J. Pillon
Published in: American Journal of Physiology-Cell Physiology, Issue 318/3, 2020, Page(s) C615-C626, ISSN 0363-6143
Publisher: American Physiological Society
DOI: 10.1152/ajpcell.00540.2019

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1

Author(s): Katrin Pfuhlmann, Sonja C. Schriever, Peter Baumann, Dhiraj G. Kabra, Luke Harrison, Sithandiwe E. Mazibuko-Mbeje, Raian E. Contreras, Eleni Kyriakou, Stephanie E. Simonds, Tony Tiganis, Michael A. Cowley, Stephen C. Woods, Martin Jastroch, Christoffer Clemmensen, Meri De Angelis, Karl-Werner Schramm, Michael Sattler, Ana C. Messias, Matthias H. Tschöp, Paul T. Pfluger
Published in: Diabetes, Issue 67/11, 2018, Page(s) 2456-2465, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db18-0146

Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage

Author(s): Audrey Sambeat, Joanna Ratajczak, Magali Joffraud, José L. Sanchez-Garcia, Maria P. Giner, Armand Valsesia, Judith Giroud-Gerbetant, Miriam Valera-Alberni, Angelique Cercillieux, Marie Boutant, Sameer S. Kulkarni, Sofia Moco, Carles Canto
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12262-x

Epigenetics and Metabolism in Health and Disease

Author(s): Evangelia Tzika, Tobias Dreker, Axel Imhof
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00361

Physiological and Epigenetic Features of Yoyo Dieting and Weight Control

Author(s): Raian E. Contreras, Sonja C. Schriever, Paul T. Pfluger
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.01015

IDH1: Linking Metabolism and Epigenetics

Author(s): Silvia Raineri, Jane Mellor
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00493

Mitochondrial stress management: a dynamic journey

Author(s): Miriam Valera-Alberni, Carles Canto
Published in: Cell Stress, Issue 2/10, 2018, Page(s) 253-274, ISSN 2523-0204
Publisher: Cell Stress
DOI: 10.15698/cst2018.10.158

Elucidating the Role of Chromatin State and Transcription Factors on the Regulation of the Yeast Metabolic Cycle: A Multi-Omic Integrative Approach

Author(s): Víctor Sánchez-Gaya, Salvador Casaní-Galdón, Manuel Ugidos, Zheng Kuang, Jane Mellor, Ana Conesa, Sonia Tarazona
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00578

Epigenetic-Transcriptional Regulation of Fatty Acid Metabolism and Its Alterations in Leukaemia

Author(s): Michael Maher, Jeannine Diesch, Raquel Casquero, Marcus Buschbeck
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00405

Carbohydrate Sensing Through the Transcription Factor ChREBP

Author(s): Paula Ortega-Prieto, Catherine Postic
Published in: Frontiers in Genetics, Issue 10, 2019, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.00472